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Abstract

In contrast to the adult pancreas, the fetal pancreas does not undergo rapid postmortem autolysis and usually is relatively well preserved at autopsy, except for stillborn fetuses with prolonged retention in utero. Samples should be obtained from the head (including the duodenum), body, and tail. Evaluation of the fetal and neonatal pancreas, particularly its endocrine component, requires familiarity with the normal changes that the stromal, exocrine, and endocrine components undergo throughout gestation. The unique features of the endocrine tissue of the fetal and neonatal pancreas must be considered before drawing conclusions as to their possible causative role in either presumed or clinically established hyperinsulinism.

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References

  1. Moore KL, Persaud, TVN: The Developing Human Clinically Oriented Embryology, 8th edn. Philadelphia: Saunders; 2008.

    Google Scholar 

  2. Bock P, Abdel-Moneim M, Egerbacher M: Development of pancreas. Microsc Res Tech 1997, 37:374–383.

    Article  PubMed  CAS  Google Scholar 

  3. Schoenwolf GC, Bleyl SB, Brauer PR, Francis-West PH: Larsen’s Human Embryology, 4th edn. Philadelphia: Churchill Livingstone Elsevier; 2009.

    Google Scholar 

  4. Peters J, Jurgensen A, Kloppel G: Ontogeny, differentiation and growth of the endocrine pancreas. Virchows Arch 2000, 436:527–538.

    Article  PubMed  CAS  Google Scholar 

  5. Hill DJ: Development of the endocrine pancreas. Rev Endocr Metab Disord 2005, 6:229–238.

    Article  PubMed  Google Scholar 

  6. Jaffe R, Hashida Y, Yunis EJ: The endocrine pancreas of the neonate and infant. Perspect Pediatr Pathol 1982, 7:137–165.

    PubMed  CAS  Google Scholar 

  7. Rahier J, Wallon J, Henquin JC: Cell populations in the endocrine pancreas of human neonates and infants. Diabetologia 1981, 20:540–546.

    Article  PubMed  CAS  Google Scholar 

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© 2011 Springer Science+Business Media, LLC

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Ruchelli, E.D., Ruchelli, E.D. (2011). Pancreas. In: Ernst, L., Ruchelli, E., Huff, D. (eds) Color Atlas of Fetal and Neonatal Histology. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0019-6_5

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  • DOI: https://doi.org/10.1007/978-1-4614-0019-6_5

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  • Print ISBN: 978-1-4614-0018-9

  • Online ISBN: 978-1-4614-0019-6

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