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Immunomodulating Role of Growth Hormone

  • Conference paper
Growth Hormone II

Part of the book series: Serono Symposia USA Norwell, Massachusetts ((SERONOSYMP))

Abstract

It is generally accepted that the immune system, although regulated to a large extent by intrinsic cellular and humoral events, is sensitive to signals generated out of the immune network, namely, in the nervous and endocrine systems. This assumption is supported by two Unes of experimental evidence: first, that spontaneous or induced alterations in the neuroendocrine system may cause functional modifications of immune reactivity (1) and, second, that receptor sites for many neuropeptides and protein hormones are present in lymphoid cells (2). On the other hand, the neuroendocrine system seems to act not only as a modulator of the immune network, but as a target for signals generated within the immune system. Examples of such interactions are the alterations that can be induced in the neuroendocrine balance either by removal of relevant lymphoid organs, such as the thymus (3), or by the functioning of the immune system itself, such as the production of lymphokines and cytokines with neuroendocrine-modulating effects (4, 5).

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Authors
  1. Nicola Fabris
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  2. Eugenio Mocchegiani
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Editor information

Editors and Affiliations

  1. Pediatric Endocrinology, All Children’s Hospital, St. Petersburg, FL, 33701, USA

    Barry B. Bercu M.D.  & Richard F. Walker Ph.D.  & 

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Fabris, N., Mocchegiani, E. (1994). Immunomodulating Role of Growth Hormone. In: Bercu, B.B., Walker, R.F. (eds) Growth Hormone II. Serono Symposia USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8372-7_9

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  • DOI: https://doi.org/10.1007/978-1-4613-8372-7_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8374-1

  • Online ISBN: 978-1-4613-8372-7

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