Dilute and Leaden, the p-Locus, Ruby-Eye, and Ruby-Eye-2
- Willys K. SilversAffiliated withDepartment of Human Genetics, School of Medicine, University of Pennsylvania
Recessive mutations at two loci of the mouse produce coat-color deviants which are phenotypically very similar. One of these mutations, described initially by Murray (1931, 1933), is known as leaden (In; chromosome 1) because when homozygous it transforms the intensely pigmented nonagouti coat color to bluish-grey;1 the other is dilute (d; chromosome 9), originally known, because of its influence on black, as the Maltese or blue dilution gene of the mouse fancy. These determinants produce a similar dilution of brown (Plate 2-E) and yellow pigment, giving the coat an overall “washed-out look” (Searle, 1968a).
- Dilute and Leaden, the p-Locus, Ruby-Eye, and Ruby-Eye-2
- Book Title
- The Coat Colors of Mice
- Book Subtitle
- A Model for Mammalian Gene Action and Interaction
- pp 83-108
- Print ISBN
- Online ISBN
- Springer New York
- Copyright Holder
- Springer-Verlag New York Inc.
- Additional Links
- Author Affiliations
- 2. Department of Human Genetics, School of Medicine, University of Pennsylvania, 19104, Philadelphia, Pennsylvania, USA
To view the rest of this content please follow the download PDF link above.