Validity and Reliability of the Alzheimer’s Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC)
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Clinical global impressions of change (CGICs) are important measures of efficacy in clinical trials. CGIC scales have been used extensively as primary outcome criteria in psychopharmacological trials and in early clinical trials for antidementia drugs (e.g., Schneider and Olin, 1994). CGICs have been reported to be the most sensitive index of change in 14 of 17 dementia trials, when compared to other measures (Lehmann, 1984).
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- Validity and Reliability of the Alzheimer’s Disease Cooperative Study-Clinical Global Impression of Change (ADCS-CGIC)
- Book Title
- Alzheimer Disease
- Book Subtitle
- From Molecular Biology to Theraphy
- Book Part
- Part VI
- pp 425-429
- Print ISBN
- Online ISBN
- Series Title
- Advances in Alzheimer Disease Therapy
- Birkhäuser Boston
- Copyright Holder
- Birkhäuser Boston
- Additional Links
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- Editor Affiliations
- 1. Department of Psychiatry, Southern Illinois University School of Medicine
- 2. Institutions Universitaires de Geriatrie de Geneve
- Author Affiliations
- 3. Department of Psychiatry, School of Geronotology, University of Southern California, Los Angeles, CA, USA
- 4. Department of Neurology, School of Geronotology, University of Southern California, Los Angeles, CA, USA
- 5. Department of Neurology, Baylor College of Medicine, Waco, TX, USA
- 6. Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
- 7. Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
- 8. Department of Psychiatry, New York University Medical Center, NY, NY, USA
- 9. Department of Neurology, University of Kentucky, Lexington, KY, USA
- 10. University of California, San Diego, CA, USA
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