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Control of Rat Gonadotropin Releasing Hormone Promoter Activity in Placental Cells

  • Conference paper
Book cover Modes of Action of GnRH and GnRH Analogs

Part of the book series: Serono Symposia, USA ((SERONOSYMP))

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Abstract

Gonadotropin releasing hormone is a hypothalamic releasing factor that controls gonadotropin subunit gene expression and ultimately both gametogenesis and gonadal steroid synthesis and biosynthesis and thus ensures reproductive competence (1) (Fig. 6.1). Many hormones, including gonadal steroids and other hypothalamic releasing factors and neurotransmitters, are thought to impact on GnRH production. An understanding of the regulation of the expression of the GnRH gene would thus allow for the study of the basic mechanisms that underlie the control of sexual maturation and infertility.

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Authors
  1. Margaret E. Wierman
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  2. Wei Sun
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  3. Chun Wang
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  4. David F. Gordon
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  5. William W. Wood
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Editor information

Editors and Affiliations

  1. Reproductive Endocrine Unit Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA

    William F. Crowley Jr. M.D.

  2. Department of Pharmacology, University of Iowa College of Medicine, Iowa City, IA, 52242-1109, USA

    P. Michael Conn Ph.D.

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© 1992 Springer-Verlag New York, Inc.

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Wierman, M.E., Sun, W., Wang, C., Gordon, D.F., Wood, W.W. (1992). Control of Rat Gonadotropin Releasing Hormone Promoter Activity in Placental Cells. In: Crowley, W.F., Conn, P.M. (eds) Modes of Action of GnRH and GnRH Analogs. Serono Symposia, USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2916-2_7

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  • DOI: https://doi.org/10.1007/978-1-4612-2916-2_7

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7718-7

  • Online ISBN: 978-1-4612-2916-2

  • eBook Packages: Springer Book Archive

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