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Drug Reaction Patterns

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Dermatopathology

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Abstract

Reactions to drugs can vary quite a bit clinically as well as histopathologically. The different types of drug reactions will be grouped below according to their clinical name or histological pattern. Although they will be listed by histological reactions pattern(s), an attempt has been made to list them in decreasing order of incidence. The four most common drug reactions in the skin are morbilliform (exanthematous), urticarial, fixed drug, and the erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum.

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Bibliography

  1. Ramdial PK, Naidoo DK. Drug-induced cutaneous pathology. J Clin Pathol. 2009;62(6):493–504. doi:10.1136/jcp.2008.058289. Epub 2009 Jan 20. Review.

    Article  PubMed  CAS  Google Scholar 

  2. Chan YC, Valenti D, Mansfield AO, Stansby G. Warfarin induced skin necrosis. Br J Surg. 2000;87(3):266–72. Review.

    Article  PubMed  CAS  Google Scholar 

  3. Nazarian RM, Van Cott EM, Zembowicz A, Duncan LM. Warfarin-induced skin necrosis. J Am Acad Dermatol. 2009;61(2):325–32.

    Article  PubMed  Google Scholar 

  4. Roujeau JC, Stern RS. Severe adverse cutaneous reactions to drugs. N Engl J Med. 1994;331(19):1272–85. Review.

    Article  PubMed  CAS  Google Scholar 

  5. Rehman RS. Histology of adverse cutaneous drug reactions. Clin Dermatol. 1986;4(1):23–9.

    Article  PubMed  CAS  Google Scholar 

  6. Gerson D, Sriganeshan V, Alexis JB. Cutaneous drug eruptions: a 5-year experience. J Am Acad Dermatol. 2008;59(6):995–9.

    Article  PubMed  Google Scholar 

  7. Naim M, Weyers W, Metze D. Histopathologic features of exanthematous drug eruptions of the macular and papular type. Am J Dermatopathol. 2011;33(7):695–704.

    Article  PubMed  Google Scholar 

  8. Kerl K. Histopathological patterns indicative of distinct adverse drug reactions. Chem Immunol Allergy. 2012;97:61–78.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, USA

    Clay Cockerell & Brian J. Hall

  2. Department of Dermatology, Brigham and Women’s Hospital, Boston, MA, USA

    Martin C. Mihm Jr.

  3. Department of Pathology and Dermatopathology, Central Texas Pathology Laboratory, Waco, TX, USA

    Cary Chisholm

  4. Department of Dermatology, Tufts Medical Center, Boston, MA, USA

    Chad Jessup

  5. Department of Pathology, Brigham and Women’s Hospital, Boston, MA, USA

    Margaret Merola

Authors
  1. Clay Cockerell
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  2. Martin C. Mihm Jr.
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  3. Brian J. Hall
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  4. Cary Chisholm
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  5. Chad Jessup
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  6. Margaret Merola
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© 2014 Springer-Verlag London

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Cockerell, C., Mihm, M.C., Hall, B.J., Chisholm, C., Jessup, C., Merola, M. (2014). Drug Reaction Patterns. In: Dermatopathology. Springer, London. https://doi.org/10.1007/978-1-4471-5448-8_14

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  • DOI: https://doi.org/10.1007/978-1-4471-5448-8_14

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5447-1

  • Online ISBN: 978-1-4471-5448-8

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