Abstract
Full-thickness defects of articular cartilage have limited to no spontaneous repair potential and can compromise patients through symptoms such as activity-related pain and swelling. Various techniques have been developed toaddress these defects, including palliative procedures such as debridement and reparative procedures such as marrow stimulation techniques (MST). Marrow stimulation techniques result in changes to the subchondral bone, including osseous overgrowth and intralesional osteophytes. Defects that had prior treatment affecting the subchondral bone have a three to seven times higher failure rate after ACI procedure when compared with non-treated defects.
In this chapter we are going to discuss the role of previous bone marrow stimulation on subsequent cartilage repair and discuss possible surgical techniques to address the altered subchondral bone in order to restore the osteochondral functional unit.
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Demange, M.K., Minas, T., Gomoll, A.H. (2014). Autologous Chondrocyte Implantation After Previous Treatment with Marrow Stimulation Techniques. In: Emans, P., Peterson, L. (eds) Developing Insights in Cartilage Repair. Springer, London. https://doi.org/10.1007/978-1-4471-5385-6_12
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DOI: https://doi.org/10.1007/978-1-4471-5385-6_12
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