Skip to main content
SpringerLink
Log in
Book cover

Renal Denervation pp 59–60Cite as

Catheter-Based Technology Alternatives for Renal Denervation: An Overview

  • Chapter
  • First Online:

  • 876 Accesses

Abstract

In the aforementioned chapters, the role of the renal sympathetic nervous system in blood pressure control has been outlined. The effect of renal sympathetic denervation on blood pressure in an animal model has been described and it has been demonstrated that renal denervation in humans causes what it intends to, a reduction in overall sympathetic tone (as demonstrated by norepinephrine spillover and muscle sympathetic nerve activity). Finally, human data on renal denervation has been summarized. In line with physiological plausibility, the promising early results of radiofrequency renal denervation have led to a surge in interest in the sympathetic nervous system and renal denervation coupled with significant investment in new technology design. Importantly, at the time of this writing, it has been announced that the Symplicity-3 trial did not meet the predefined primary endpoint. Specifics regarding the outcome of the trial are not available, yet.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Kaltenbach B, Id D, Franke JC, et al. Renal artery stenosis after renal sympathetic denervation. J Am Coll Cardiol. 2012;60(25):2694–5.

    Article  PubMed  Google Scholar 

  2. Vonend O, Antoch G, Rump LC, Blondin D. Secondary rise in blood pressure after renal denervation. Lancet. 2012;380(9843):778.

    Article  PubMed  Google Scholar 

  3. Schenk EA, El-Badawi A. Dual innervation of arteries and arterioles. A histochemical study. Z Zellforsch Mikrosk Anat. 1968;91(2):170–7.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. CardioVascular Center Frankfurt, Seckbacher, Landstrasse 65, 60389, Frankfurt, Germany

    Stefan C. Bertog MD, FACC, FSCAI & Horst Sievert MD, FESC, FACC, FSCAI

Authors
  1. Stefan C. Bertog MD, FACC, FSCAI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Horst Sievert MD, FESC, FACC, FSCAI
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Horst Sievert MD, FESC, FACC, FSCAI .

Editor information

Editors and Affiliations

  1. St. Luke's Medical Center, Phoenix, Arizona, USA

    Richard R. Heuser

  2. Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

    Markus Schlaich

  3. CardioVascular Center Frankfurt Sankt Katharinen, Frankfurt, Germany

    Horst Sievert

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag London

About this chapter

Cite this chapter

Bertog, S.C., Sievert, H. (2015). Catheter-Based Technology Alternatives for Renal Denervation: An Overview. In: Heuser, R., Schlaich, M., Sievert, H. (eds) Renal Denervation. Springer, London. https://doi.org/10.1007/978-1-4471-5223-1_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-5223-1_6

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5222-4

  • Online ISBN: 978-1-4471-5223-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation