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Occupational Cancers pp 107–126Cite as

Pancreatic Cancer

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Abstract

Pancreatic cancer is a fatal malignancy associated with rapid progression. One year relative survival rates are less than 30 %, and nearly all patients die from the disease within 7 years of surgery. It is estimated that 43,920 men and women will be diagnosed with pancreatic cancer and 37,390 will die of the disease in 2012. Although there have been improvements made in the diagnostic and prognosis of pancreatic cancer, these changes are minor. Smoking is the only established nonheritable risk factor for pancreatic cancer; however, only about 30 % of the cases can be attributed to smoking. Although results are inconclusive, obesity, diabetes, alcohol consumption, and chronic pancreatitis have also been suggested as risk factors for pancreatic cancer. Given this poorly understood etiology, prevention of this deadly disease continues to remain a challenge.

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Authors and Affiliations

  1. Department of Abdominal Tumours Surgery, Center of Pancreatic Tumours, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing, China

    Yingtai Chen MD, PhD & Chengfeng Wang MD

  2. Department of Environmental Health Sciences, Yale University, School of Public Health, 60 College Street, New Haven, CT, 06520, USA

    Yawei Zhang MD, PhD, MPH

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  1. Yingtai Chen MD, PhD
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  2. Chengfeng Wang MD
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  3. Yawei Zhang MD, PhD, MPH
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Correspondence to Yawei Zhang MD, PhD, MPH .

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  1. Helsinki University Central Hospital and Finnish Institute of Occupational Health, Helsinki, Finland

    Sisko Anttila

  2. Icahn School of Medicine at Mount Sinai, New York, New York, USA

    Paolo Boffetta

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Chen, Y., Wang, C., Zhang, Y. (2014). Pancreatic Cancer. In: Anttila, S., Boffetta, P. (eds) Occupational Cancers. Springer, London. https://doi.org/10.1007/978-1-4471-2825-0_5

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