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Retinal Vascular Disease

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Lee's Ophthalmic Histopathology
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Abstract

Ischaemic retinal vascular diseases ultimately lead to glaucoma and are found in the globes that are enucleated to relieve intractable pain in a blind eye. The clinical diagnosis is usually “neovascular glaucoma” with the addition of “central retinal vein occlusion” or “diabetes,” but occasionally, rarer entities such as retinopathy of prematurity or Coats’ disease will be seen at this end stage. Angiogenic factors released by the ischaemic retina are important in the pathogenesis of these retinal vascular diseases. Central retinal artery occlusion, posterior ciliary artery occlusion, ophthalmic artery occlusion, hypertension and disseminated intravascular coagulation are rarely associated with neovascular glaucoma. Choroidal neovascularisation (disciform degeneration) and age related macular degeneration are included in this chapter although they do not per se lead to anterior segment neovascularisation.

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Roberts, F., Thum, C.K. (2014). Retinal Vascular Disease. In: Lee's Ophthalmic Histopathology. Springer, London. https://doi.org/10.1007/978-1-4471-2476-4_4

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