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Anaplastic Thyroid Cancer

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Tips and Tricks in Endocrine Surgery

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Abstract

Anaplastic, or undifferentiated, thyroid cancer is one of the most aggressive solid tumors with an extremely poor prognosis. It is believed that around 50 % of anaplastic thyroid cancers arise from a prior or coexistent differentiated thyroid carcinoma. The loss of the tumor suppressor gene p53 is an important step in this process.

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Further Reading

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  • ZYBRESTAT(TM) (CA4P) improves overall survival in a phase 2/3 trial (FACT Study) of patients with Anaplastic Thyroid Cancer (ATC). OXiGENE press release of Phase 2/3 results Sept 2010 posted at http://www.globenewswire.com/newsroom/news.html?d=201261.

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Author information

Authors and Affiliations

  1. Department of Oncology, Queen Elizabeth Hospital Cancer Centre, Edgbaston, Birmingham, West Midlands, B15 2TH, UK

    Caroline Connolly MBChB, FRCR & John Glaholm

Authors
  1. Caroline Connolly MBChB, FRCR
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  2. John Glaholm
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Corresponding author

Correspondence to Caroline Connolly MBChB, FRCR .

Editor information

Editors and Affiliations

  1. ENT Department, Queen Elizabeth Hospital, Birmingham, United Kingdom

    John C. Watkinson

  2. Department of Endocrine Surgery, University Hospital of Wales, Cardiff, United Kingdom

    David M. Scott-Coombes

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© 2014 Springer-Verlag London

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Connolly, C., Glaholm, J. (2014). Anaplastic Thyroid Cancer. In: Watkinson, J., Scott-Coombes, D. (eds) Tips and Tricks in Endocrine Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-2146-6_17

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  • DOI: https://doi.org/10.1007/978-1-4471-2146-6_17

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  • Publisher Name: Springer, London

  • Print ISBN: 978-0-85729-982-6

  • Online ISBN: 978-1-4471-2146-6

  • eBook Packages: MedicineMedicine (R0)

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