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Genetic Evolution of Neural Network Architectures

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Artificial Neural Networks in Biomedicine

Part of the book series: Perspectives in Neural Computing ((PERSPECT.NEURAL))

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Abstract

Feed forward back-propagation artificial neural networks (ANNs) have been used to predict outcomes in a variety of biomedical settings [1],[2]. Their advantages and disadvantages compared with standard statistical methods (SSMs) relate to different appraisals of three major problems that are common to all methods for estimation: (1) agreement, (2) stability and (3) transparency. In this chapter we consider these problems and propose a method which addresses some of them using procedures called genetic algorithms. Our arguments are illustrated by comparing the performance of the various prediction methods in predicting the occurrence of depression after mania [3].

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References

  1. Baxt, W. Application of neural networks to clinical medicine. Lancet, 346:1135–38, 1995.

    Article  Google Scholar 

  2. Cross, S., Harrison, R., and Kennedy, R. Introduction to neural networks. Lancet, 346:1075–79, 1995.

    Article  Google Scholar 

  3. Lucas, C., Rigby, J., and Lucas, S. The occurence of depression following mania: A method of predicting vulnerable cases. Br.J.Psych, 154:705–08, 1989.

    Article  Google Scholar 

  4. White, H. Learning in artificial neural networks: A statistical approach. Neural Comp., 1:425–64, 1989.

    Article  Google Scholar 

  5. Cybenko, G. Approximation by superpositions of a sigmoidal function. Math Control Sig Sys, 2:303–314, 1989.

    Article  MathSciNet  MATH  Google Scholar 

  6. Hornik, K., Stinchcombe, M., and White, H. Multilayer feedforward networks are universal approximators. Neural Networks, 2(5):359–366, 1989.

    Article  Google Scholar 

  7. Minsky, M. and Papert, S. Perceptrons. Cambridge, Mass, CA.: MIT Press, 1989.

    Google Scholar 

  8. Wyatt, J. Nervous about artificial neural networks? Lancet, 346:1175–77, 1995.

    Article  Google Scholar 

  9. Press, W., Teukolsky, S., and W. Vetterling, Numerical recipes in FORTRAN. The art of scientific computing. 2 ed. Cambridge University Press: Cambridge, UK, 1994.

    Google Scholar 

  10. Jefferson, M., et al. Comparison of a genetic algorithm neural network (GANN) with logistic regression for predicting outcome after surgery for non-small cell lung cancer (NSCLC). Cancer, 79:1338–42, 1997.

    Article  Google Scholar 

  11. Jefferson, M., et al. Prediction of Haemorrhagic Blood Loss with a Genetic Algorithm Neural Network (GANN). J Appl. Physiol, 84(1):357–61, 1998.

    MathSciNet  Google Scholar 

  12. Goldberg, D. Genetic Algorithms in Search, Optimization and Machine Learning. 1st ed. Reading, Mass., USA: Addison-Wesley, 1989.

    Google Scholar 

  13. Yao, X. A review of evolutionary artificial neural networks. Intelligent Sys, 8(4):539–67, 1993.

    Article  Google Scholar 

  14. Branke, J. Evolutionary algorithms for neural network design and training. Karlsruhe University: Karlsruhe, Germany, 1995.

    Google Scholar 

  15. Balakrishnan, K., and Vasant, H. Evolutionary design of neural architectures: A preliminary taxonomy and guide to Literature. Iowa State University: Ames, Iowa, USA, 1995.

    Google Scholar 

  16. Narayanan, M., and Lucas, S. A genetic algorithm to improve a neural network to predict a patient’s response to warfarin. Methods Inform Med, 32:55–58, 1993.

    Google Scholar 

  17. Dybowski, R. et al. Prediction of outcome in critically ill patients using artificial neural network synthesized by genetic algorithm. Lancet, 347:114–650, 1996.

    Article  Google Scholar 

  18. Rummelhart, D., Hinton, G., and Williams, R. Learning internal representations by error propagation., in Parallel distributed processing: explorations in the microstructure of cognition., D. Rummelhart and D. McClelland, Editors. MIT Press: Cambrige, Mass, USA. 1986.

    Google Scholar 

  19. Morgan, H. The incidence of depressive symptoms during recovery from hypomania. Brit J Psych, 120:537–39, 1972.

    Article  Google Scholar 

  20. Hart, A., and Wyatt, J. Evaluating black boxes as medical decision-aids: Issues arising from a study of neural networks. Med Inf (lond).,15:229–36, 1990.

    Article  Google Scholar 

  21. Amari, S. Learning and statistical inference, in Handbook of Brain Theory and Neural Networks, M. Arib, Editor. MIT Press: Cambridge, Mass, USA. 1995.

    Google Scholar 

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© 2000 Springer-Verlag London

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Jefferson, M.F., Pendleton, N., Lucas, S.B. (2000). Genetic Evolution of Neural Network Architectures. In: Lisboa, P.J.G., Ifeachor, E.C., Szczepaniak, P.S. (eds) Artificial Neural Networks in Biomedicine. Perspectives in Neural Computing. Springer, London. https://doi.org/10.1007/978-1-4471-0487-2_4

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  • DOI: https://doi.org/10.1007/978-1-4471-0487-2_4

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-85233-005-7

  • Online ISBN: 978-1-4471-0487-2

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