Abstract
Noise-induced hearing loss (NIHL) is the most common cause of acquired hearing loss among persons younger than age 40. The major pathological basis of NIHL is mechanical stress to cochlear structures. During noise exposure, mechanical forces drive the basilar membrane to oscillate. Excessive motion of the basilar membrane causes a cascade of structural changes in cochlear sensory cells and their supporting cells, which, in turn, compromise cochlear function. Although acoustic overexposure affects both the peripheral and the central auditory systems, the peripheral organ is the primary target of acoustic exposure.
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Hu, B. (2012). Noise-Induced Structural Damage to the Cochlea. In: Le Prell, C.G., Henderson, D., Fay, R.R., Popper, A.N. (eds) Noise-Induced Hearing Loss. Springer Handbook of Auditory Research, vol 40. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9523-0_5
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