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Calcium-sensing Receptor and Neoplastic Transformation

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Calcium-Sensing Receptor

Part of the book series: Endocrine updates ((ENDO,volume 19))

Abstract

There is increasing evidence from epidemiological studies that some of the most frequent human cancers are associated with a specific nutritional pattern: For example, an increased risk of breast cancer is believed to result from high dietary fat and/or low intake of vitamin D and calcium (1,2,3). Similarly, it has been known for a long time that colorectal cancer shows a strong positive correlation with dietary fat, while low vitamin D and dietary calcium are additional independent risk factors for the disease (4,5,6). From the study of Garland et al. (5) it can be implied that the incidence of colorectal cancer may be reduced by approximately 70% if daily calcium intake is raised from 800 to 1400 mg. The incidence of prostate cancer is also clearly linked to high fat consumption, whereas studies on a possible association with dietary calcium levels did not yield conclusive results (7,8).

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Authors and Affiliations

  1. Department of Pathophysiology, University of Vienna Medical School, A-1090, Vienna, Austria

    Enikö Kállay Ph.D., Heide S. Cross M.D. & Meinrad Peterlik M.D.

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  1. Enikö Kállay Ph.D.
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  2. Heide S. Cross M.D.
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  3. Meinrad Peterlik M.D.
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Editors and Affiliations

  1. Endocrine-Hypertension Division Department of Medicine, Brigham and Women’s Hospital Harvard Medical School, Boston, Massachusetts, USA

    Naibedya Chattopadhyay  & Edward M. Brown  & 

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Kállay, E., Cross, H.S., Peterlik, M. (2003). Calcium-sensing Receptor and Neoplastic Transformation. In: Chattopadhyay, N., Brown, E.M. (eds) Calcium-Sensing Receptor. Endocrine updates, vol 19. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9256-7_12

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  • DOI: https://doi.org/10.1007/978-1-4419-9256-7_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4861-0

  • Online ISBN: 978-1-4419-9256-7

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