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Overview of Diet-Gene Interactions and the Example of Xanthophylls

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Bio-Farms for Nutraceuticals

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 698))

Abstract

This chapter provides an overview of diet-gene interaction and the role of dietary factors in human health and disease. Human master control genes that regulate processes of fundamental importance, such as cell proliferation and the immune response, are introduced and their modulation by nutraceuticals, produced by plants and photosynthetic microbes, is reviewed. Emphasis is placed on antioxidants and polyunsaturated fatty acids as regulators of master control genes. Furthermore, a case study is presented on xanthophylls, a group of carotenoids with multiple health benefits in the protection against eye disease and other chronic diseases, as well as the synergism between xanthophylls and other dietary factors. Lastly, dietary sources of the xanthophylls zeaxanthin and lutein are reviewed and their enhancement via genetic engineering is discussed.

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Authors and Affiliations

  1. Department of Ecology and Evolutionary Biology, University of Colorado, Boulder, Colorado, 80309-0334, USA

    Barbara Demmig-Adams

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  1. Barbara Demmig-Adams
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  2. William W. Adams III
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Editors and Affiliations

  1. Institute of Crystallography, Department of Agrofood and Department of Molecular Design, National Council of Research, Area of Research of Rome, Monterotondo Scalo, Rome, Italy

    Maria Teresa Giardi PhD  & Giuseppina Rea PhD  & 

  2. Institute of General Physiology and Biochemistry, Department of Molecular Sciences Applied to Biosystems, DISMAB, University of Milan, Milan, Italy

    Bruno Berra PhD

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Demmig-Adams, B., Adams, W.W. (2010). Overview of Diet-Gene Interactions and the Example of Xanthophylls. In: Giardi, M.T., Rea, G., Berra, B. (eds) Bio-Farms for Nutraceuticals. Advances in Experimental Medicine and Biology, vol 698. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-7347-4_2

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