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Diagnostic Criteria, Classification and Nomenclature for Bladder Pain Syndrome

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Book cover Bladder Pain Syndrome

Abstract

Because the term “interstitial cystitis” (IC) has different meanings in different centres and different parts of the world, the International Society for the Study of Bladder Pain Syndrome (ESSIC) has worked to create a consensus on definitions, diagnosis and classification in an attempt to overcome the lack of international agreement on various aspects of IC. ESSIC has discussed definitions, diagnostic criteria and disease classification in four meetings and extended email correspondence.

As the name IC has become misleading, it was agreed to name the disease bladder pain syndrome (BPS). This name is in line with recent nomenclature recommendations by the European Association of Urology and is based on the axial structure of the International Association for the Study of Pain classification. BPS would be diagnosed on the basis of chronic pelvic pain, pressure or discomfort perceived to be related to the urinary bladder accompanied by at least one other urinary symptom such as persistent urge to void or urinary frequency. Confusable diseases as the cause of the symptoms must be excluded. Classification of BPS types might be performed according to findings at cystoscopy with hydrodistention and morphologic findings in bladder biopsies. The presence of other organ symptoms as well as cognitive, behavioural, emotional and sexual symptoms should be addressed.

The text of this chapter is partly based on a paper published previously: Van de Merwe JP, Nordling J, Bouchelouche P, et al., European Urology 2008;53:60–7.

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References

  1. Gillenwater JY, Wein AJ. Summary of the National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases Workshop on Interstitial Cystitis, National Institutes of Health, Bethesda, Maryland, August 28–29, 1987. J Urol. 1988;140:203–6.

    PubMed  CAS  Google Scholar 

  2. Wein AJ, Hanno P, Gillenwater JY. An introduction to the problem. In: Hanno P, Staskin DR, Krane RJ, Wein AJ, editors. Interstitial cystitis. London: Springer-Verlag; 1990. pp. 3–15.

    Google Scholar 

  3. Hanno PM, Landis JR, Matthews-Cook Y, Kusek J, Nyberg Jr L. The diagnosis of interstitial cystitis revisited: lessons learned from the National Institutes of Health Interstitial Cystitis Database study. J Urol. 1999;161:553–7.

    Article  PubMed  CAS  Google Scholar 

  4. Holm-Bentzen M, Jacobsen F, Nerstrom B, Lose G, Kristensen JK, Pedersen RH, Krarup T, Feggetter J, Bates P, Barnard R, et al. Painful bladder disease: clinical and pathoanatomical differences in 115 patients. J Urol. 1987;138:500–2.

    PubMed  CAS  Google Scholar 

  5. Witherow RO, Gillespie L, McMullen L, Goldin RD, Walker MM. Painful bladder syndrome – a clinical and immunopathological study. Br J Urol. 1989;64:158–61.

    Article  PubMed  CAS  Google Scholar 

  6. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, van Kerrebroeck P, Victor A, Wein A. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002;21:167–78.

    Article  PubMed  Google Scholar 

  7. Fall M, Baranowski AP, Elneil S, Engeler D, Huges J, Messelink EJ, et al. EAU guidelines on chronic pelvic pain. Eur Urol. 2010;57(1):35–48.

    Article  PubMed  Google Scholar 

  8. Abrams P, Andersson KE, Brubaker L, Cardozo L, Cottenden A, Denis L, Donovan J, Fonda D, Fry C, Griffiths D, et al. Recommendations of the International Scientific Committee: evaluation and treatment of urinary incontinence, pelvic organ prolapse and faecal incontinence. In: Abrams P, Cardozo L, Khoury S, Wein A, editors. Incontinence. Paris: Health Publications Ltd; 2005. p. 1589–630.

    Google Scholar 

  9. van de Merwe JP, Nordling J: Interstitial cystitis: definitions and confusable diseases. Essic Meeting 2005 Baden. European Urology Today. 2006;18:6, 7, 16, 17.

    Google Scholar 

  10. van de Merwe JP, Nordling J, Bouchelouche P, Bouchelouche K, Cervigni M, Daha LK, Elneil S, Fall M, Hohlbrugger G, Irwin P, et al. Diagnostic criteria, classification, and nomenclature for painful bladder syndrome/interstitial cystitis: an ESSIC proposal. Eur Urol. 2008;53:60–7.

    Article  PubMed  Google Scholar 

  11. ARHP. Definition and nomenclature of interstitial cystitis/painful bladder syndrome (IC/PBS). In: Screening, treatment, and management of interstitial cystitis/painful bladder syndrome; Washington, DC. Association of Reproductive Health Professionals; 2007.p. 5–7.

    Google Scholar 

  12. Homma Y. Disease name, definition, diagnosis and evaluation. In: 2nd ICICJ International Consultation on Interstitial Cystitis; 2007; Kyoto, Japan.

    Google Scholar 

  13. Homma Y, Ueda T, Tomoe H, Lin AT, Kuo HC, Lee MH, Lee JG, Kim DY, Lee KS. Clinical guidelines for interstitial cystitis and hypersensitive bladder syndrome. Int J Urol. 2009;16:597–615.

    Article  PubMed  Google Scholar 

  14. Ueda T, Sant GR, Hanno PM, Yoshimura N. Proceedings of the International Consultation on Interstitial Cystitis. March 28–30, 2003. Kyoto, Japan. Int J Urol. 2003;10(Suppl i–iv):S1–70.

    Article  PubMed  Google Scholar 

  15. Fries JF, Hochberg MC, Medsger Jr TA, Hunder GG, Bombardier C. Criteria for rheumatic disease. Different types and different functions. The American College of Rheumatology Diagnostic and Therapeutic Criteria Committee. Arthritis Rheum. 1994;37:454–62.

    Article  PubMed  CAS  Google Scholar 

  16. Nordling J, Anjum FH, Bade JJ, Bouchelouche K, Bouchelouche P, Cervigni M, Elneil S, Fall M, Hald T, Hanus T, et al. Primary evaluation of patients suspected of having interstitial cystitis (IC). Eur Urol. 2004;45:662–9.

    Article  PubMed  CAS  Google Scholar 

  17. Abrams P. Urgency: the key to defining the overactive bladder. BJU Int. 2005;96 Suppl 1:1–3.

    Article  PubMed  Google Scholar 

  18. Hanno P. Toward optimal health: Philip Hanno, M.D., M.P.H., discusses improved management of painful bladder syndrome (interstitial cystitis). Interview by Jodi R. Godfrey. J Womens Health (Larchmt). 2007;16(1):3–8.

    Article  Google Scholar 

  19. Sirinian E, Azevedo K, Payne CK. Correlation between 2 interstitial cystitis symptom instruments. J Urol. 2005;173:835–40.

    Article  PubMed  Google Scholar 

  20. Merskey H, Bogduk N. Classification of chronic pain, descriptions of chronic pain syndromes and definitions of pain terms. Seattle: IASP Press; 2002.

    Google Scholar 

  21. Trachtenberg J, Roehrborn CG. Updated results of a randomized, double-blind, multicenter sham-controlled trial of microwave thermotherapy with the Dornier Urowave in patients with symptomatic benign prostatic hyperplasia. Urowave Investigators Group. World J Urol. 1998;16:102–8.

    Article  PubMed  CAS  Google Scholar 

  22. Tsai YS, Lin JS, Tong YC, Tzai TS, Yang WH, Chang CC, Cheng HL, Lin YM, Jou YC. Transurethral microwave thermotherapy for symptomatic benign prostatic hyperplasia: short-term experience with Prostcare. Urol Int. 2000;65:89–94.

    Article  PubMed  CAS  Google Scholar 

  23. Wagrell L, Schelin S, Nordling J, Richthoff J, Magnusson B, Schain M, Larson T, Boyle E, Duelund J, Kroyer K, et al. Three-year follow-up of feedback microwave thermotherapy versus TURP for clinical BPH: a prospective randomized multicenter study. Urology. 2004;64:698–702.

    Article  PubMed  Google Scholar 

  24. Abrams P, Hanno P, Wein A. Overactive bladder and painful bladder syndrome: there need not be confusion. Neurourol Urodyn. 2005;24:149–50.

    Article  PubMed  Google Scholar 

  25. Warren JW, Meyer WA, Greenberg P, Horne L, Diggs C, Tracy JK. Using the International Continence Society’s definition of painful bladder syndrome. Urology. 2006;67:1138–42. discussion 1142–1133.

    Article  PubMed  Google Scholar 

  26. Blaivas JG, Panagopoulos G, Weiss JP, Somaroo C, Chaikin DC. The urgency perception score: validation and test-retest. J Urol. 2007;177:199–202.

    Article  PubMed  Google Scholar 

  27. Chambers GK, Fenster HN, Cripps S, Jens M, Taylor D. An assessment of the use of intravesical potassium in the diagnosis of interstitial cystitis. J Urol. 1999;162:699–701.

    Article  PubMed  CAS  Google Scholar 

  28. Diggs C, Meyer WA, Langenberg P, Greenberg P, Horne L, Warren JW. Assessing urgency in interstitial cystitis/painful bladder syndrome. Urology. 2007;69:210–4.

    Article  PubMed  Google Scholar 

  29. Parsons CL, Greenberger M, Gabal L, Bidair M, Barme G. The role of urinary potassium in the pathogenesis and diagnosis of interstitial cystitis. J Urol. 1998;159:1862–6. discussion 1866–1867.

    Article  PubMed  CAS  Google Scholar 

  30. Hornby AS, Cowie AP, editors. Oxford advanced learner’s dictionary of current English. Oxford: University Press; 1985: 946

    Google Scholar 

  31. Parsons CL, Stein PC, Bidair M, Lebow D. Abnormal sensitivity to intravesical potassium in interstitial cystitis and radiation cystitis. Neurourol Urodyn. 1994;13:515–20.

    Article  PubMed  CAS  Google Scholar 

  32. Parsons CL, Albo M. Intravesical potassium sensitivity in patients with prostatitis. J Urol. 2002;168:1054–7.

    Article  PubMed  Google Scholar 

  33. Yilmaz U, Liu YW, Rothman I, Lee JC, Yang CC, Berger RE. Intravesical potassium chloride sensitivity test in men with chronic pelvic pain syndrome. J Urol. 2004;172:548–50.

    Article  PubMed  CAS  Google Scholar 

  34. Hanno P. Is the potassium sensitivity test a valid and useful test for the diagnosis of interstitial cystitis? Against. Int Urogynecol J Pelvic Floor Dysfunct. 2005;16:428–9.

    Article  PubMed  Google Scholar 

  35. Parsons CL, Rosenberg MT, Sassani P, Ebrahimi K, Koziol JA, Zupkas P. Quantifying symptoms in men with interstitial cystitis/prostatitis, and its correlation with potassium-sensitivity testing. BJU Int. 2005;95:86–90.

    Article  PubMed  Google Scholar 

  36. Fall M, Baranowski A, Fowler CJ, Hughes J, Lepinard V, Malone-Lee JG, Messelink EJ, Oberpenning F, Osborne JL, Schumacher S. Guidelines on chronic pelvic pain. European Association of Urology Guidelines. 2007;1–70

    Google Scholar 

  37. Keay SK, Szekely Z, Conrads TP, Veenstra TD, Barchi Jr JJ, Zhang CO, Koch KR, Michejda CJ. An antiproliferative factor from interstitial cystitis patients is a frizzled 8 protein-related sialoglycopeptide. Proc Natl Acad Sci U S A. 2004;101:11803–8.

    Article  PubMed  CAS  Google Scholar 

  38. Keay S, Zhang CO, Hise MK, Hebel JR, Jacobs SC, Gordon D, Whitmore K, Bodison S, Gordon N, Warren JW. A diagnostic in vitro urine assay for interstitial cystitis. Urology. 1998;52:974–8.

    Article  PubMed  CAS  Google Scholar 

  39. Peeker R, Fall M. Toward a precise definition of interstitial cystitis: further evidence of differences in classic and nonulcer disease. J Urol. 2002;167:2470–2.

    Article  PubMed  Google Scholar 

  40. Hanno PM. Painful bladder syndrome/interstitial cystitis and related disorders. In: Wein AJ, editor. Campbell-Walsh Urology. 9th ed. Philadelphia: Saunders; 2007. pp. 330–70.

    Google Scholar 

  41. Janicki TI. Chronic pelvic pain as a form of complex regional pain syndrome. Clin Obstet Gynecol. 2003;46:797–803.

    Article  PubMed  Google Scholar 

  42. Abrams P, Baranowski A, Berger RE, Fall M, Hanno P, Wesselmann U. A new classification is needed for pelvic pain syndromes–are existing terminologies of spurious diagnostic authority bad for patients? J Urol. 2006;175:1989–90.

    Article  PubMed  Google Scholar 

  43. Hanno P, Keay S, Moldwin R, Van Ophoven A. International consultation on IC – Rome, September 2004/forging an international consensus: progress in painful bladder syndrome/interstitial cystitis. Report and abstracts. Int Urogynecol J Pelvic Floor Dysfunct. 2005;16 Suppl 1:S2–34.

    PubMed  Google Scholar 

  44. Habermacher GM, Chason JT, Schaeffer AJ. Prostatitis/chronic pelvic pain syndrome. Annu Rev Med. 2006;57:195–206.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Jørgen Nordling MD, Dr.med.Sci, FEBU .

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van de Merwe, J.P., Nordling, J., Bouchelouche, P., Cervigni, M., Fall, M., Wyndaele, JJ. (2013). Diagnostic Criteria, Classification and Nomenclature for Bladder Pain Syndrome. In: Nordling, J., Wyndaele, J., van de Merwe, J., Bouchelouche, P., Cervigni, M., Fall, M. (eds) Bladder Pain Syndrome. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6929-3_3

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  • DOI: https://doi.org/10.1007/978-1-4419-6929-3_3

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