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Chemicals of Emerging Concern in the Great Lakes Basin: An Analysis of Environmental Exposures

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Reviews of Environmental Contamination and Toxicology Volume 207

Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 207))

Abstract

Environmental analysis and monitoring have long been recognized as a means for assessing environmental quality. Within the Great Lakes watershed, the governments of the United States and Canada, together with collaborating agencies, have performed numerous surveys of environmental contaminants in the air, water, sediments, and biota. Environmental monitoring programs are necessary to develop comprehensive descriptions of environmental quality, including at spatial and temporal scales, and to provide a sound basis for effective measures, strategies, and policies to address environmental problems (Calamari et al. 2000). While an important use of monitoring data is to inform environmental risk assessment, information gained from environmental measurements is also important for priority setting in regard to addressing the potential hazards of chemical contaminants.

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References

  • Advanced Industrial Science and Technology (AIST), National Institute of (2007) AIST Risk Assessment Document Series No. 4 Bisphenol A. Research Center for Chemical Risk Management, AIST Tsukuba West, Tsukuba, Ibaraki, JP

    Google Scholar 

  • Andresen JA, Muir D, Ueno D, Darling C, Theobald N, Bester K (2007) Emerging pollutants in the North Sea in comparison to Lake Ontario, Canada. Environ Toxicol Chem 26:1081–1089

    CAS  Google Scholar 

  • Balmer ME, Poiger T, Droz C, Romanin K, Bergqvist PA, Muller MD, Buser HR (2004) Occurrence of methyl triclosan, a transformation product of the bactericide triclosan, in fish from various lakes in Switzerland. Environ Sci Technol 38:390–395

    CAS  Google Scholar 

  • Baronti C, Curini R, D’Ascenzo G, Dicorcia A, Gentili A, Samperi R (2000) Monitoring natural and synthetic estrogens at activated sludge sewage treatment plants and in a receiving river water. Environ Sci Technol 34:5059–5066

    CAS  Google Scholar 

  • Batterman S, Chernyak S, Gwynn E, Cantonwine D, Jia C, Begnoche L, Hickey JP (2007) Trends of brominated diphenyl ethers in fresh and archived Great Lakes fish (1979–2005). Chemosphere 69:444–457

    CAS  Google Scholar 

  • Bennett ER, Metcalf CD (1998) Distribution of alkylphenol compounds in Great Lakes sediments, United States and Canada. Environ Toxicol Chem 17:1230–1235

    CAS  Google Scholar 

  • Bennett ER, Metcalfe CD (2000) Distribution of degradation products of alkylphenol ethoxylates near sewage treatment plants in the Lower Great Lakes, North America. Environ Toxicol Chem 19:784–792

    CAS  Google Scholar 

  • Bennie DT, Sullivan CA, Lee HB, Peart TE, Maguire RJ (1997) Occurrence of alkylphenols and alkylphenol mono- and diethoxylates in natural waters of the Laurentian Great Lakes basin and the upper St. Lawrence River. Sci Total Environ 193:263–275

    CAS  Google Scholar 

  • Boulanger B, Peck AM, Schnoor JL, Hornbuckle KC (2005) Mass budget of perfluorooctane surfactants in Lake Ontario. Environ Sci Technol 39:74–79

    CAS  Google Scholar 

  • Boulanger B, Vargo J, Schnoor JL, Hornbuckle KC (2004) Detection of perfluorooctane surfactants in Great Lakes water. Environ Sci Technol 38:4064–4070

    CAS  Google Scholar 

  • Boyd GR, Reemtsma H, Grimm DA, Mitra S (2003) Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada. Sci Total Environ 331:135–149

    Google Scholar 

  • Calamari D, Jones K, Kannan K, Lecloux A, Olsson M, Thurman M, Zannetti P (2000) Monitoring as an indicator of persistence and long-range transport. In: Klečka GM (ed) Evaluation of persistence and long-range transport of organic chemicals in the environment. Society of Environmental Toxicology and Chemistry, Pensacola, FL, pp 205–244

    Google Scholar 

  • Canadian Council of Ministers of the Environment (CCME) (2001) Canadian water quality guidelines for the protection of aquatic life: nonylphenol and its ethoxylates. Environment Canada Publication Number 12999. ISBN 10896997-34-1. Environment Canada, Ottawa, ON, Canada

    Google Scholar 

  • CCME (2002) Canadian sediment quality guidelines for the protection of aquatic life: summary tables. Updated 2002. In: Canadian Council of Ministers of the Environment, Canadian environmental quality guidelines, 1999. Winnipeg, MB, Canada

    Google Scholar 

  • CCME (2007) Canadian water quality guidelines for the protection of aquatic life: summary table. Update 7.1, December, 2007. In: Canadian Council of Ministers of the Environment, Canadian environmental quality guidelines, 1999. Winnipeg, MB, Canada

    Google Scholar 

  • CCME (2008) Canadian water quality guidelines for the protection of aquatic life: chlorpyrifos. Updated 2008. In: Canadian Council of Ministers of the Environment, Canadian environmental quality guidelines, 1999. Winnipeg, MB, Canada

    Google Scholar 

  • Canadian Environmental Protection Act (CEPA) (1997) Environmental assessments of priority substances under the Canadian Environmental Protection Act: guidance manual version 1.0. Chemical Evaluation Division, Commercial Chemicals Evaluation Branch, report EPS/2/CC/3E. Environment Canada, Ottawa, ON, Canada

    Google Scholar 

  • Carlson DL, Basu I, Hites RA (2004) Annual variations of pesticide concentrations in Great Lakes precipitation. Environ Sci Technol 38:5290–5296

    CAS  Google Scholar 

  • Carlson DL, Swackhamer DL (2006) Results from the U.S. Great Lakes fish monitoring program and effects of lake processes on bioaccumulative contaminant concentrations. J Great Lakes Res 32:370–385

    CAS  Google Scholar 

  • Chernyak SM, Rice CP, Quintal RT, Begnoche LJ, Hickney JP, Vunyard BT (2005) Time trends (1983–1999) for organochlorines and polybrominated diphenyl ethers in rainbow smelt (Osmerus mordax) from Lakes Michigan, Huron, and Superior, USA. Environ Toxicol Chem 24:1632–1641

    CAS  Google Scholar 

  • Christian MS, Parker RM, Hoberman AM, Diener RM, Api AM (1999) Developmental toxicity studies of four fragrances in rats. Toxicol Lett 111:169–174

    CAS  Google Scholar 

  • Chu S, Haffner GD, Letcher RJ (2005) Simultaneous determination of tetrabromobisphenol A, tetrachlorobisphenol A, bisphenol A and other halogenated analogues in sediment and sludge by high performance liquid chromatography–electrospray tandem mass spectrometry. J Chromatogr A 1097:25–32

    CAS  Google Scholar 

  • Chu S, Metcalfe CD (2007) Analysis of paroxetine, fluoxetine, and norfluoxetine in fish tissues using pressurized liquid extraction, mixed mode solid phase extraction cleanup, and liquid chromatography–tandem mass spectrometry. J Chromatogr A 1163:112–118

    CAS  Google Scholar 

  • Cortes DR, Basu I, Sweet CW, Brice KA, Hoff RM, Hites RA (1998) Temporal trends in gas-phase concentrations of chlorinated pesticides measured at the shores of the Great Lakes. Environ Sci Technol 32:1920–1927

    CAS  Google Scholar 

  • Daughton CG (2001) Pharmaceuticals in the environment: overarching issues and overview. In: Daughton CG, Jones-Lepp T (eds) Pharmaceuticals and personal care products in the environment: scientific and regulatory issues, American Chemical Society Symposium Series 791. Washington, DC, pp 2–38

    Google Scholar 

  • Department for Environment, Food and Rural Affairs (DEFRA) (2004) Perfluorooctane sulphonate; risk reduction strategy and analysis of advantages and drawbacks. Final Report, August 2004. Norfolk, UK

    Google Scholar 

  • Dsikowitzky L, Schwarzbauer J, Littke R (2002) Distribution of polycyclic musks in water and particulate matter of the Lippe River (Germany). Org Geochem 33:1747–1758

    CAS  Google Scholar 

  • Environment Canada (EC) (2006a) Ecological screening assessment report on perfluorooctane sulfonate, its salts and its precursors that contain the C8F17SO2, C8F17SO3, or C8F17SO2N moiety. Environment Canada, Ottawa, ON, Canada

    Google Scholar 

  • EC (2006b) Ecological screening assessment report on polybrominated diphenyl ethers (PBDEs). Environment Canada, Ottawa, ON, Canada

    Google Scholar 

  • EC (2008) Follow-up report on a PSL1 assessment for which data were insufficient to conclude whether the substances were “toxic” to the environment and to human health: chlorinated paraffins. Environment Canada, Ottawa, ON, Canada

    Google Scholar 

  • Environment Canada and Health Canada (EC and HC) (2001) Priority substances list assessment report: nonylphenol and its ethoxylates. Environment Canada and Health Canada, Ottawa, ON, Canada

    Google Scholar 

  • EC and HC (2008) Screening assessment for the challenge: phenol, 4,4′-(1-methylethylidene)bis-(bisphenol A). Environment Canada and Health Canada, Ottawa, ON, Canada

    Google Scholar 

  • European Commission (EUC) (2001) European Union risk assessment report: diphenyl ether, pentabromo derivative. Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2002a) European Union risk assessment report: 4-nonylphenol (branched) and nonylphenol. Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2002b) European Union risk assessment report: bis(pentabromophenyl) ether. Final report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2003a) Technical guidance document in support of Commission Directive 93/67/EEC on risk assessment for new notified substances and commission regulation (EC) No. 1488/94 on risk assessment for existing substances. Part II. ECSC-EC-EAEC. Brussels, Belgium

    Google Scholar 

  • EUC (2003b) European Union risk assessment report: diphenyl ether, octabromo derivative. Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2003c) Directive 2003/11/EC of the European Parliament and of the Council of 6 February 2003 amending for the 24th time Council directive 76/769 relating to restrictions on the marketing and use of certain dangerous substances and preparations (pentabromodiphenyl ether and octabromodiphenyl ether). Official Journal L 042

    Google Scholar 

  • EUC (2003d) European Union risk assessment report: naphthalene. Final report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2004) European Union risk assessment report: 1,4-dichlorobenzene. Final report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2005a) 5-tert-Butyl-2,4,6-trinitro-m-xylene (musk xylene). Summary risk assessment report. European Chemicals Bureau, Ispra, Italy

    Google Scholar 

  • EUC (2005b) European Union risk assessment report: 4′-tert-butyl-2′,6′-dimethyl-3′,5′-dinitroacetophenone (musk ketone). Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2005c) European Union risk assessment report: alkanes, C14-17, chloro (MCCP): part 1 – environment. Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2005d) European Union risk assessment report: tetrachloroethylene. Final report; part 1 – environment. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2006a) Directive 2000/60/EC of the European Parliament and of the Council on environmental quality standards in the field of water policy and amending Directive 2000/60/EC. Official Journal COM(2006)397

    Google Scholar 

  • EUC (2006b) European Union risk assessment report: phenol. Final report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008a) Updated European Union risk assessment report – 4,4′-isopropylidenediphenol (bisphenol-A); CAS No: 80-05-7; EINECS No: 201-245-8. Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008b) European Union risk assessment report: 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one (AHTN). Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008c) European Union risk assessment report: 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-2-benzopyran (HHCB). Final Report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008d) Updated risk assessment of alkanes, C10-13, chloro. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008e) European Union risk assessment report: anthracene. Final report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008f) European Union risk assessment report: coal-tar pitch, high temperature. Final report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • EUC (2008 g) European Union risk assessment report: hexabromocyclododecane. Final draft report. Office for Official Publications of the European Communities, Luxembourg

    Google Scholar 

  • Fox GA (2006) Back to the future: rediscovering the requirement for monitoring in the Great Lakes Water Quality Agreement. In: Expert consultation on emerging issues of the Great Lakes in the 21st Century. Report of the Great Lakes Science Advisory Board to the International Joint Commission, Windsor, ONtario, Canada

    Google Scholar 

  • Furdui VI, Stock NL, Ellis DA, Butt CM, Whittle DM, Crozier PW, Reiner EJ, Muir DCG, Mabury SA (2007) Spatial distribution of perfluoroalkyl contaminants in Lake Trout from the Great Lakes. Environ Sci Technol 41:1554–1559

    CAS  Google Scholar 

  • Gatermann R, Biselli S, Huhnerfuss H, Rimkus GG, Hecker M, Karbe L (2002) Synthetic musks in the environment, part 1: species-dependent bioaccumulation of polycyclic and nitro musk fragrances in freshwater fish and mussels. Arch Environ Contam Toxicol 42:437–446

    CAS  Google Scholar 

  • Gauthier LT, Hebert CE, Weseloh DVC, Letcher RJ (2007) Current-use flame retardants in the eggs of herring gulls (Larus argentatus) from the Laurentian Great Lakes. Environ Sci Technol 41:4561–4567

    CAS  Google Scholar 

  • Gauthier LT, Herbert CE, Weseloh DVC, Letcher RJ (2008) Dramatic changes in the temporal trends of polybrominated diphenyl ethers (PBDEs) in herring gull eggs from the Laurentian Great Lakes: 1982–2006. Environ Sci Technol 42:1524–1530

    CAS  Google Scholar 

  • Giesy JP, Kannan K (2001) Global distribution of perfluorooctane sulfonate in wildlife. Environ Sci Technol 35:1339–1342

    CAS  Google Scholar 

  • Giesy JP, Naile JE, Khim JS, Jones PD, Newsted JL (2010) Aquatic toxicology of perfluorinated chemicals. Rev Environ Contam Toxicol 202:1–52

    CAS  Google Scholar 

  • Gilliom RJ, Barbash JE, Crawford CG, Hamilton PA, Martin JD, Nakagaki N, Nowell LH, Scott JC, Stackelberg PE, Thelin TP, Wolock DM (2006) The quality of our Nation’s waters: pesticides in the Nation’s streams and ground water, 1992–2001. U.S. Geological Survey Circular 1291, Reston, VA

    Google Scholar 

  • Gouin T, Harner T, Daly GL, Wania F, Mackay D, Jones KC (2005) Variability of concentrations of polybrominated diphenyl ethers and polychlorinated biphenyls in air: implications for monitoring, modeling and control. Atmos Environ 39:151–166

    CAS  Google Scholar 

  • Hao C, Lissemore L, Nguyen B, Kleywegt S, Yang P, Solomon K (2006) Determination of pharmaceuticals in environmental waters by liquid chromatography/electrospray ionization/tandem mass spectrometry. Anal Bioanal Chem 384:505–513

    CAS  Google Scholar 

  • Hekster FM, de Voogt P, Pijnenburg AMCM, Laane RWPM (2002) Perfluoroalkylated substances; aquatic environmental assessment. RIKZ Report 2002.043, July 1, 2002. Den Haag, Netherlands

    Google Scholar 

  • Hoh E, Hites RA (2005) Brominated flame retardants in the atmosphere of the east-central United States. Environ Sci Technol 39:7794–7802

    CAS  Google Scholar 

  • Hoh E, Zhu L, Hites RA (2005) Novel flame retardants, 1,2-bis(2,4,6-tribromophenoxy)-ethane and 2,3,4,5,6-pentabromoethylbenzene, in United States’ environmental samples. Environ Sci Technol 39:2472–2477

    CAS  Google Scholar 

  • Hoh E, Zhu LY, Hites RA (2006) Dechlorane Plus, a chlorinated flame retardant, in the Great Lakes. Environ Sci Technol 40:1184–1189

    CAS  Google Scholar 

  • Houde M, Muir DCG, Tomy GT, Whittle DM, Teixeira C, Moore S (2008) Bioaccumulation and trophic magnification of short- and medium-chain chlorinated paraffins in food webs from Lake Ontario and Lake Michigan. Environ Sci Technol 42:3893–3899

    CAS  Google Scholar 

  • Hua WY, Bennett ER, Letcher RJ (2005) Triclosan in waste and surface waters from the upper Detroit River by liquid chromatography–electrospray–tandem quadrupole mass spectrometry. Environ Int 31:621–630

    CAS  Google Scholar 

  • Hua WY, Bennett ER, Letcher RJ (2006a) Ozone treatment and the depletion of detectable pharmaceuticals and atrazine herbicide in drinking water sourced from the upper Detroit River, ON, Canada. Water Res 40:2259–2266

    CAS  Google Scholar 

  • Hua WY, Bennett ER, Maio X, Metcalfe CD, Letcher RJ (2006b) Seasonality effects on pharmaceuticals and s-triazine herbicides in wastewater effluent and surface water from the Canadian side of the upper Detroit River. Environ Toxicol Chem 25:2356–2365

    CAS  Google Scholar 

  • International Joint Commission (IJC) (1987) Revised Great Lakes water quality agreement of 1978 – agreement with annexes in terms of reference, between the United States and Canada signed at Ottawa October 16, 1983 as amended by protocol signed November 18, 1987. International Joint Commission Canada and United States, Windsor, ON, Canada

    Google Scholar 

  • James R, Hites RA (1999) Chlorothalonil and dacthal in Great Lakes air and precipitation samples. J Great Lakes Res 25:406–411

    CAS  Google Scholar 

  • Jones-Lepp T (2006) Chemical markers of human waste contamination: analysis of urobilin and pharmaceuticals in source waters. J Environ Monit 8:472–478

    CAS  Google Scholar 

  • Kannan K, Kober JL, Kang Y, Masunaga S (2001) Polychlorinated naphthalenes, biphenyls, dibenzo-p-dioxins, and dibenzofurans as well as polycyclic aromatic hydrocarbons and alkylphenols in sediment from the Detroit and Rouge Rivers, Michigan, USA. Environ Toxicol Chem 20:1878–1889

    CAS  Google Scholar 

  • Kannan K, Corsolini S, Falandysz J, Oehme G, Focardi S, Giesy JP (2002) Perfluorooctanesulfonate and related fluorinated hydrocarbons in marine mammals, fishes, and birds from coasts of the Baltic and the Mediterranean Seas. Environ Sci Technol 36:3210–3216

    CAS  Google Scholar 

  • Kannan K, Keith TL, Naylor CG, Staples CA, Giesy JP (2003) Nonylphenol and nonylphenol ethoxylates in fish, sediment and water from the Kalamazoo River, Michigan. Arch Environ Contam Toxicol 4:77–82

    Google Scholar 

  • Kannan K, Yun SH, Evans TJ (2005a) Chlorinated, brominated, and perfluorinated contaminants in livers of polar bears from Alaska. Environ Sci Technol 39:9057–9063

    CAS  Google Scholar 

  • Kannan K, Tao L, Sinclair E, Pastva SD, Jude DJ, Giesy JP (2005b) Perfluorinated compounds in aquatic organisms at various trophic levels in a Great Lakes food chain. Arch Environ Contam Toxicol 48:559–566

    CAS  Google Scholar 

  • Keith TL, Snyder SA, Naylor CG, Staples CA, Summer C, Kannan K, Giesy JP (2001) Identification and quantitation of nonylphenol ethoxylates and nonylphenol in fish tissues from Michigan. Environ Sci Technol 35:10–13

    CAS  Google Scholar 

  • Klečka GM, Zabik J, Woodburn K, Naylor CG, Staples CA, Huntsman BE (2007) Exposure analysis of C8- and C9-alkylphenol, alkylphenol ethoxylates and their metabolites in surface water systems within the United States. Human Ecol Risk Assess 13:792–822

    Google Scholar 

  • Klečka GM, Staples CA, Clark KE, van der Hoeven N, Thomas DE, Hentges SG (2009) Exposure analysis of bisphenol A in surface water systems in North America and Europe. Environ Sci Technol 43:6145–6150

    Google Scholar 

  • Kolpin DW, Furlong ET, Meyer MT, Thurman EM, Zaugg SD, Barber LB, Buxton HT (2002) Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999–2000: a national reconnaissance. Environ Sci Technol 36:1202–1211

    CAS  Google Scholar 

  • Lehman-McKeeman LD, Caudill D, Vassallo JD, Pearce RE, Madan A, Parkinson A (1999) Effects of musk xylene and musk ketone on rat hepatic cytochrome P450 enzymes. Toxicol Lett 111:105–115

    CAS  Google Scholar 

  • Lindstrom A, Buerge IJ, Poiger T, Bergqvist PA, Muller MD, Buser HR (2002) Occurrence and environmental behavior of the bactericide triclosan and its methyl derivative in surface waters and in wastewater. Environ Sci Technol 36:2322–2329

    Google Scholar 

  • Lissemore L, Hao C, Yang P, Sibley PK, Mabury S, Solomon K (2006) An exposure assessment for selected pharmaceuticals within a watershed in Southern Ontario. Chemosphere 64:717–729

    CAS  Google Scholar 

  • Lopes TJ, Furlong ET (2001) Occurrence and potential adverse effects of semi volatile organic compounds in streambed sediment, United States, 1992–1995. Environ Toxicol Chem 20:727–737

    CAS  Google Scholar 

  • Luross JM, Alaee M, Sergeant DB, Cannon CM, Whittle DM, Solomon KR, Muir DCG (2002) Spatial distribution of polybrominated diphenyl ethers and polybrominated biphenyls in lake trout from the Laurentian Great Lakes. Chemosphere 46:665–672

    CAS  Google Scholar 

  • Manchester-Neesvig JB, Valters K, Sonzogni WC (2001) Comparison of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in Lake Michigan salmonids. Environ Sci Technol 35:1072–1077

    CAS  Google Scholar 

  • Martin JW, Whittle DM, Muir DCG, Mabury SA (2004) Perfluoroalkyl contaminants in a food web from Lake Ontario. Environ Sci Technol 38:5379–5385

    CAS  Google Scholar 

  • Martin JW, Ellis DA, Mabury SA, Hurley MD, Wallington TJ (2006) Atmospheric chemistry of perfluoroalkanesulfonamides: kinetic and product studies of the OH radical and Cl atom initiated oxidation of N-ethyl perfluorobutanesulfonamide. Environ Sci Technol 40:864–872

    CAS  Google Scholar 

  • Marvin CH, Painter S, Tomy GT, Stern GA, Braekevelt E, Muir DCG (2003) Spatial and temporal trends in short-chain chlorinated paraffins in Lake Ontario sediments. Environ Sci Technol 37:4561–4568

    CAS  Google Scholar 

  • Marvin CH, Tomy GT, Alaee M, Macinnis G (2006) Distribution of hexabromocyclododecane in Detroit River suspended sediments. Chemosphere 64:268–275

    CAS  Google Scholar 

  • Mayer T, Bennie D, Rosa F, Rekas G, Palabrica V, Schachtschneider J (2007) Occurrence of alkylphenolic substances in a Great Lakes coastal marsh, Cootes Paradise, ON, Canada. Environ Pollut 147:683–900

    CAS  Google Scholar 

  • McDowell DC, Metcalfe CD (2001) Phthalate esters in sediments near a sewage treatment plant outflow in Hamilton Harbour, Ontario: SFE extraction and environmental distribution. J Great Lakes Res 27:3–9

    CAS  Google Scholar 

  • Melcer H, Klečka G, Monteith H, Staples C (2007) Wastewater Treatment of Alkylphenols and their Ethoxylates; a State of the Science Review. Report for the Water Environment Federation, Alexandria, VA

    Google Scholar 

  • Metcalfe CD, Miao XS, Koenig BG, Struger J (2003) Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada. Environ Toxicol Chem 22:2881–2889

    CAS  Google Scholar 

  • Miller SM, Sweet CW, DePinto JV, Hornbuckle KC (2000) Atrazine and nutrients in precipitations: results from the Lake Michigan mass balance study. Environ Sci Technol 34:55–61

    CAS  Google Scholar 

  • Monteiro SC, Boxall BA (2010) Occurrence and fate of human pharmaceuticals in the environment. Rev Environ Contam Toxicol 202:53–154

    CAS  Google Scholar 

  • Moore S, Vromet L, Rondeau B (2004) Comparison of meta-stable atom bombardment and electron capture negative ionization for the analysis of polychloroalkanes. Chemosphere 54:453–459

    CAS  Google Scholar 

  • Muir D, Alaee M, Scott B (2006) Identifying potential and emerging chemical contaminants in the Great Lakes. In: Expert consultation on emerging issues of the Great Lakes in the 21st Century. Report of the Great Lakes Science Advisory Board to the International Joint Commission, Windsor, ON, Canada

    Google Scholar 

  • Muir D, Bennie D, Teixeria C, Fisk A, Tomy G, Stern G, Whittle M (2001) Short chain chlorinated paraffins: are they persistent and bioaccumulative? In: Lipnick RL, Jannson B, Mackay D (eds) Persistent, bioaccumulative, and toxic chemicals II. Assessment and new chemicals. ACS Symposium Series 773, American Chemical Society, Washington, DC

    Google Scholar 

  • Norstrom RJ, Simon M, Moisey J, Wakeford B, Weseloh DVC (2002) Geographical distribution (2000) and temporal trends (1981–2000) of brominated diphenyl ethers in Great Lakes herring gull eggs. Environ Sci Technol 36:4786–4789

    Google Scholar 

  • Organization for Economic Cooperation and Development (OECD) (2002) Cooperation on existing chemicals: hazard assessment of perfluorooctane sulfonate and its salts. Environment Directorate, Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology, report ENV/JM/RD(2002)17/Final. Paris, France

    Google Scholar 

  • O’Toole S, Metcalfe C (2006) Synthetic musks in fish from urbanized areas of the lower Great Lakes, Canada. J Great Lakes Res 32:361–369

    Google Scholar 

  • Peck AM, Hornbuckle KC (2004) Synthetic musk fragrances in Lake Michigan. Environ Sci Technol 38:367–372

    CAS  Google Scholar 

  • Peck AM, Hornbuckle KC (2006) Synthetic musk fragrances in urban and rural air of Iowa and the Great Lakes. Atmos Environ 40:6101–6111

    CAS  Google Scholar 

  • Peck AM, Linebaugh EK, Hornbuckle KC (2006) Synthetic musk fragrances in Lake Erie and Lake Ontario sediment cores. Environ Sci Technol 40:5629–5635

    CAS  Google Scholar 

  • Purdom CE, Hardiman PA, Bye VJ, Eno NC, Tyler CR, Sumpter JP (1994) Estrogenic effects of effluents from sewage treatment works. Chem Ecol 8:275–285

    CAS  Google Scholar 

  • Qiu X, Marvin CH, Hites RA (2007) Dechlorane plus and other flame retardants in a sediment core from Lake Ontario. Environ Sci Technol 41:6014–6019

    CAS  Google Scholar 

  • Rice CP, Chernyak SM, Begnoche L, Quintal R, Hickey J (2002) Comparisons of PBDE composition and concentration in fish collected from the Detroit River, MI and Des Plaines River, IL. Chemosphere 49:731–737

    CAS  Google Scholar 

  • Rice CP, Schmitz-Afonso I, Loyo-Rosales JE, Link E, Thoma R, Fay L, Altfater D, Camp MJ (2003) Alkylphenol and alkylphenol ethoxylates in carp, water, and sediment from the Cuyahoga River, Ohio. Environ Sci Technol 37:3747–3754

    CAS  Google Scholar 

  • Ricking M, Schwarzbauer J, Hellou J, Svenson A, Zitko V (2003) Polycyclic aromatic musk compounds in sewage treatment plant effluents of Canada and Sweden – first results. Mar Pollut Bull 46:410–417

    CAS  Google Scholar 

  • Rimkus G, Rimkus B, Wolf M (1994) Nitro musks in human adipose tissue and breast milk. Chemosphere 28:421–432

    CAS  Google Scholar 

  • Rimkus GG, Butte W, Geyer HJ (1997) Critical considerations on the analysis and bioaccumulation of musk xylene and other synthetic nitro musks in fish. Chemosphere 35:1497–1507

    CAS  Google Scholar 

  • Rimkus GG (1999) Polycyclic musk fragrances in the aquatic environment. Toxicol Lett 111:37–56

    CAS  Google Scholar 

  • Routledge EJ, Sheahan D, Desbrow C, Sumpter JP (1998) Identification of estrogenic chemicals in STW effluent. 2. In vivo responses in trout and roach. Environ Sci Technol 32:1559–1565

    CAS  Google Scholar 

  • Sabik H, Gagne F, Blaise C, Marcogliese DJ, Jeannot R (2003) Occurrence of alkylphenol polyethoxylates in the St. Lawrence River and their bioconcentration by mussels (Elliptio complanata). Chemosphere 51:349–356

    CAS  Google Scholar 

  • Sandstrom MW, Koplin DW, Thurman M, Zaugg SD (2005) Widespread detection of N,N-diethyl-m-toluamide in U.S. streams: comparison with concentrations of pesticides, personal care products, and other organic wastewater compounds. Environ Toxicol Chem 24:1029–1034

    CAS  Google Scholar 

  • Schultz MM, Barofsky DF, Field JA (2003) Fluorinated alkyl surfactants. Environ Eng Sci 20:487–501

    CAS  Google Scholar 

  • Scott BF, Moody CA, Spencer C, Small JM, Muir DCG, Mabury SA (2006) Analysis for perfluorocarboxylic acids/anions in surface waters and precipitation using GC–MS and analysis of PFOA from large-volume samples. Environ Sci Technol 40:6405–6410

    CAS  Google Scholar 

  • Servos MR, Maguire RJ, Bennie DT, Lee HB, Cureton PM, Davidson N, Sutcliff R, Rawn DFK (2003) An ecological risk assessment of nonylphenol and its ethoxylates in the aquatic environment. Hum Ecol Risk Assess 9:569–587.

    CAS  Google Scholar 

  • Servos MR, Smith M, McInnis R, Burnison BK, Lee HB, Seto P, Backus S (2007) The presence of selected pharmaceuticals and the antimicrobial triclosan in drinking water in Ontario, Canada. Water Qual Res J Can 42:130–137

    CAS  Google Scholar 

  • Shen L, Wania F, Lei YD, Teixeira CD, Muir DCG, Xiao H (2006) Polychlorinated biphenyls and polybrominated diphenyl ethers in the North American atmosphere. Environ Pollut 144:434–444

    CAS  Google Scholar 

  • Simonich SL, Begley WM, Debaere G, Eckhoff WS (2000) Trace analysis of fragrance materials in wastewater and treated wastewater. Environ Sci Technol 34:959–965

    CAS  Google Scholar 

  • Sinclair E, Mayack DT, Roblee K, Yamashita N, Kannan K (2006) Occurrence of perfluoroalkyl surfactants in water, fish, and birds from New York State. Arch Environ Contam Toxicol 50:398–410

    CAS  Google Scholar 

  • Song W, Ford JC, Li A, Mills WJ, Rockne KJ, Buckley DR (2004) Polybrominated diphenyl ethers in the sediments of the Great Lakes. 1. Lake Superior. Environ Sci Technol 38:3286–3293

    CAS  Google Scholar 

  • Song W, Ford JC, Li A, Sturchio NC, Rockne KJ, Buckley DR, Mills WJ (2005a) Polybrominated diphenyl ethers in the sediments of the Great Lakes. 3. Lakes Ontario and Erie. Environ Sci Technol 39:5600–5605

    CAS  Google Scholar 

  • Song W, Li A, Ford JC, Sturchio NC, Rockne KJ, Buckley DR, Mills WJ (2005b) Polybrominated diphenyl ethers in the sediments of the Great Lakes. 2. Lakes Michigan and Huron. Environ Sci Technol 39:3474–3479

    CAS  Google Scholar 

  • Strandberg B, Dodder NG, Basu I, Hites RA (2001) Concentrations and spatial variations of polybrominated diphenyl ethers and other organohalogen compounds in Great Lakes air. Environ Sci Technol 35:1078–1083

    CAS  Google Scholar 

  • Streets S, Henderson S, Stoner A, Carlson D, Simcik M, Swackhamer D (2006) Partitioning and bioaccumulation of PBDEs and PCBs in Lake Michigan. Environ Sci Technol 40:7263–7269

    CAS  Google Scholar 

  • Struger J, Fletcher T (2007) Occurrence of lawn care and agricultural pesticides in the Don and Humber River Watersheds (1998–2002). J Great Lakes Res 33:887–905

    CAS  Google Scholar 

  • Struger J, L’Italien S, Sverko E (2004) In-use pesticide concentrations in surface waters of the Laurentian Great Lakes (1994–2000). J Great Lakes Res 30:435–450

    CAS  Google Scholar 

  • Struger J, Sverko E, Grabuski J, Fletcher T, Marvin C (2007) Occurrence and fate of methoprene compounds in urban areas of Southern Ontario, Canada. Bull Environ Contam Toxicol 79:168–171

    CAS  Google Scholar 

  • Struger J, Thompson D, Staznik B, Martin P, McDaniel T, Marvin C (2008) Occurrence of glyphosate in surface waters of southern Ontario. Bull Environ Contam Toxicol 80:378–384

    CAS  Google Scholar 

  • Sun P, Backus S, Blanchard P, Hites RA (2006a) Temporal and spatial trends of organochlorine pesticides in Great Lakes precipitation. Environ Sci Technol 40:2135–2141

    CAS  Google Scholar 

  • Sun P, Blanchard P, Brice K, Hites RA (2006b) Atmospheric organochlorine pesticide concentrations near the Great Lakes: temporal and spatial trends. Environ Sci Technol 40:6587–6593

    CAS  Google Scholar 

  • Sverko E, Tomy GT, Marvin CH, Zaruk D, Reiner E, Helm PA, Hill B, McCarry BE (2008) Dechlorane plus levels in sediment of the lower Great Lakes. Environ Sci Technol 42:361–366

    CAS  Google Scholar 

  • Tertuliana JS, Alvarez DA, Furlong ET, Meyer MT, Zaugg SD, Koltun GF (2008) Occurrence of organic wastewater compounds in the Tinkers Creek watershed and two other tributaries to the Cuyahoga river, Northeast Ohio. USGS Report 2008-5173, Reston, VA

    Google Scholar 

  • Tomy GT, Budakowski W, Halldorson T, Whittle DM, Keir MJ, Marvin C, MacInnis G, Alaee M (2004) Biomagnification of alpha- and gamma-hexabromocyclododecane isomers in a Lake Ontario food web. Environ Sci Technol 38:2298–2303

    CAS  Google Scholar 

  • Tomy GT, Pleskach K, Ismail N, Whittle DM, Helm PA, Sverko E, Zaruk D, Marvin CH (2007) Isomers of Dechlorane plus in Lake Winnipeg and Lake Ontario food webs. Environ Sci Technol 41:2249–2254

    CAS  Google Scholar 

  • Tuduri L, Harner T, Blanchard P, Li YF, Poissant L, Waite DT, Murphy C, Belzer W (2006) A review of currently used pesticides (CUPs) in Canadian air and precipitation. Part 2: regional information and perspectives. Atmos Environ 40:1579–1589

    CAS  Google Scholar 

  • United Kingdom Environment Agency (UK EA) (2005) Environmental risk evaluation report: 4-tert-octylphenol. London, UK

    Google Scholar 

  • United States Environmental Protection Agency (US EPA) (1991) RM1 decision package: chlorinated paraffins – environmental risk assessment. US Environmental Protection Agency, Washington, DC

    Google Scholar 

  • United States Environmental Protection Agency (US EPA) (1993) RM2 exit briefing on chlorinated paraffins and olefins. US Environmental Protection Agency, Washington, DC

    Google Scholar 

  • United States Environmental Protection Agency (US EPA) (1996) RM-1 document for para-nonylphenol. US Environmental Protection Agency, Washington, DC

    Google Scholar 

  • United States Environmental Protection Agency (US EPA) (1998) Reregistration eligibility decision (RED) for DEET. EPA 738-R-98-010. US Environmental Protection Agency, Washington, DC

    Google Scholar 

  • United States Environmental Protection Agency (US EPA) (1999) National recommended water quality criteria. Report 822-Z-99-001. U.S. Environmental Protection Agency, Washington, DC

    Google Scholar 

  • U.S. Environmental Protection Agency (US EPA) (2005) Aquatic life ambient water quality criteria – nonylphenol. Report 822-R-05-005. U.S. Environmental Protection Agency, Washington, DC

    Google Scholar 

  • U.S. Environmental Protection Agency (US EPA) (2006) National recommended water quality criteria. Office of Water (4304T). U.S. Environmental Protection Agency, Washington, DC

    Google Scholar 

  • Valters K, Li H, Alaee M, D’Sa I, Marsh G, Bergman A, Letcher RJ (2005) Polybrominated diphenyl ethers and hydroxylated and methoxylated brominated and chlorinated analogues in the plasma of fish from the Detroit River. Environ Sci Technol 39:5612–5619

    CAS  Google Scholar 

  • Venier M, Hites RA (2008) Flame retardants in the atmosphere near the Great Lakes. Environ Sci Technol 42:4745–4751

    CAS  Google Scholar 

  • Walker JD (2006) Can QSARs identify emerging pollutants that will threaten the Great Lakes ecosystem? In: Expert consultation on emerging issues of the Great Lakes in the 21st century. Report of the Great Lakes Science Advisory Board to the International Joint Commission, Windsor, ON, Canada

    Google Scholar 

  • Walraven N, Laane RWPM (2008) Assessing the discharge of pharmaceuticals along the Dutch coast of the North Sea. Rev Environ Contam Toxicol 199:1–18

    Google Scholar 

  • Winkler M, Kopf G, Hauptvogel C, Neu T (1998) Fate of artificial musk fragrances associated with suspended particulate matter (SPM) from the River Elbe (Germany) in comparison to other organic contaminants. Chemosphere 37:1139–1156

    CAS  Google Scholar 

  • Yamagishi T, Miyazaki T, Horii S, Kaneko S (1981) Identification of musk xylene and musk ketone in fresh-water fish collected from the Tama River, Tokyo. Bull Environ Contam Toxicol 26:656–662

    CAS  Google Scholar 

  • Zhu LY, Hites RA (2004) Temporal trends and spatial distributions of brominated flame retardants in archived fishes from the Great Lakes. Environ Sci Technol 38:2779–2784

    CAS  Google Scholar 

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Acknowledgements

The authors wish to thank Sheridan Haack, Derek Muir, and Mike Murray for assistance with identifying relevant studies. The authors also thank John Struger for providing additional details on pesticide monitoring conducted in Canada.

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  1. The Dow Chemical Company, Midland, MI, USA

    Gary Klečka & Rebecca Currie

  2. The University of Iowa, Iowa City, IA, USA

    Carolyn Persoon

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Correspondence to Gary Klečka .

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Klečka, G., Persoon, C., Currie, R. (2010). Chemicals of Emerging Concern in the Great Lakes Basin: An Analysis of Environmental Exposures. In: Whitacre, D. (eds) Reviews of Environmental Contamination and Toxicology Volume 207. Reviews of Environmental Contamination and Toxicology, vol 207. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6406-9_1

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