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Cardiovascular Disease Risk

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Handbook of Genomics and the Family

Part of the book series: Issues in Clinical Child Psychology ((ICCP))

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Abstract

The precise genetic mutations that directly cause or play some role in coronary artery disease (CAD), cardiomyopathies, cardiac arrhythmias, and pulmonary artery hypertension have begun to be identified. The majority of the genetic mutations of hypertrophic and dilated cardiomyopathies have also been described. Many of the genes responsible for cardiac arrhythmias, such as long QT syndrome, have been identified as well. In this chapter, we will specifically address the genetics of CAD, hyperlipidemias, obesity, and other transmitted cardiovascular risks from parent to child. We will review the complex interaction of genetics and the environment that predispose families and children to cardiovascular disease and the implications for health and disease prevention. The understanding of the genetic basis of CAD and the interaction between genes and the environment may improve our prevention, treatment, and care of the sequelae of CAD.

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  1. Children’s National Medical Center, Washington, DC, USA

    Suma Potiny & Sarah Clauss

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  1. Suma Potiny
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  2. Sarah Clauss
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  1. Division of Health Outcomes & Health Beh, Department of Oncology, Georgetown University, Whitehaven St, NW 3300, Washington, 20007, District of Columbia, USA

    Kenneth P. Tercyak

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Potiny, S., Clauss, S. (2010). Cardiovascular Disease Risk. In: Tercyak, K. (eds) Handbook of Genomics and the Family. Issues in Clinical Child Psychology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-5800-6_13

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