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Structural Causes of Dyspepsia

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Dyspepsia in Clinical Practice

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Abstract

The definition of dyspepsia and its interpretation, as previously discussed in Chap. 1, are challenging. Encompassing a constellation of symptoms located in the retrosternal area, as well as in the upper abdomen, and potentially indicative of a number of ­different pathological processes, dyspepsia may have many and, in some cases, a number of causes. Although certain symptoms may seem, at first sight, more suggestive of the underlying pathology, efforts to identify which symptoms correlate with particular disease processes have been largely unsuccessful. In a seminal paper, Crean and colleagues attempted to define such clinico–pathological correlations and found that most supposed predictive symptoms did not hold up when critically examined. The most striking feature of this study, perhaps, was the uncertainty exhibited by clinicians when attempting to diagnose functional dyspepsia (FD), despite adequate investigation. This contrasted markedly with clinician certainty in diagnosing irritable bowel syndrome (IBS) [1].

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Authors and Affiliations

  1. Alimentary Pharmabiotic Centre, Department of Medicine, Cork University Hospital, Clinical Sciences Building, Cork, Ireland

    Daniel Schmidt-Martin

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  1. Daniel Schmidt-Martin
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  2. Eamonn M. M. Quigley
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Correspondence to Daniel Schmidt-Martin .

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  1. Medical School in Zagreb, University of, Department of Gastroenterology and Hepat, University Hospital “Sestre milosrdnice”, Vinogrdska Str. 29, Zagreb, 10000, Croatia

    Marko Duvnjak

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Schmidt-Martin, D., Quigley, E.M.M. (2011). Structural Causes of Dyspepsia. In: Duvnjak, M. (eds) Dyspepsia in Clinical Practice. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1730-0_4

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  • DOI: https://doi.org/10.1007/978-1-4419-1730-0_4

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