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Aminolevulinic Acid: Actinic Keratosis and Photorejuvenation

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Abstract

ALA-PDT is a safe and effective treatment for nonhyperkeratotic lesions. Although FDA-approved for use with a blue light source, other laser and light sources have demonstrated promise in the treatment of actinic keratosis during PDT. Shorter incubation times maintain AK clearance rates but decrease the occurrence of phototoxic adverse events. With careful patient selection, ALA-PDT allows selective field treatment of precancerous skin lesions with improvement in overall photodamage. Patient satisfaction is high and cosmetic results can be excellent.

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Palm, M., Goldman, M.P. (2011). Aminolevulinic Acid: Actinic Keratosis and Photorejuvenation. In: Gold, M. (eds) Photodynamic Therapy in Dermatology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1298-5_2

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