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Atypical Teratoid Rhabdoid Tumor

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Abstract

Atypical teratoid/rhabdoid tumors are malignant high grade embryonal (WHO Grade IV) tumors seen in children often below the age of 3 years and rarely above the age of 6 years. Account for 10% of tumors in infants with slight male predominance, M:F ratio = 2:1 Characteristically poorly differentiated, contain rhabdoid cells with divergent differentiation to form epithelial, mesenchymal, neuronal, and glial components and may be associated with a subpopulation of primitive neuroectodermal cells.

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Author information

Authors and Affiliations

  1. Section of Neuropathology and Molecular Neuropathology Laboratory, Department of Pathology, Texas Children’s Hospital, Baylor College of Medicine, Houston, TX, USA

    Adekunle M. Adesina M.D., Ph.D. (Professor of Pathology, Medical Director)

  2. Department of Radiology, Texas Children’s Hospital, Baylor College of Medicine, Houston, TX, USA

    J. Hunter M.B., B.S. (Associate Professor of Radiology)

  3. Department of Pathology, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA

    L. Rorke-Adams M.D. (Clinical Professor)

Authors
  1. Adekunle M. Adesina M.D., Ph.D.
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  2. J. Hunter M.B., B.S.
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  3. L. Rorke-Adams M.D.
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Editor information

Editors and Affiliations

  1. Dept. Pathology, Baylor College of Medicine, Baylor Plaza 1, Houston, 77030, U.S.A.

    Adekunle M. Adesina

  2. School of Medicine, University of California, Parnassus Ave. 505, San Francisco, 94143, U.S.A.

    Tarik Tihan

  3. VCU Medical Center, Virginia Commonwealth University, E. Marshall Street 1200, Richmond, 23298, U.S.A.

    Christine E. Fuller

  4. Children's Hospital Boston, Harvard Medical School, Longwood Ave. 300, Boston, 02115, U.S.A.

    Tina Young Poussaint

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Adesina, A.M., Hunter, J., Rorke-Adams, L. (2010). Atypical Teratoid Rhabdoid Tumor. In: Adesina, A., Tihan, T., Fuller, C., Poussaint, T. (eds) Atlas of Pediatric Brain Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1062-2_8

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  • DOI: https://doi.org/10.1007/978-1-4419-1062-2_8

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-1061-5

  • Online ISBN: 978-1-4419-1062-2

  • eBook Packages: MedicineMedicine (R0)

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