Ganglioglioma and Gangliocytoma

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These are neuroepithelial tumors composed of mature neurons (gangliocytoma) or a mixed population of ganglion cells and glial cells (ganglioglioma). Well differentiated gangliocytomas are classified as WHO grade I while gangliogliomas may be classified as WHO grade I or II. Anaplastic ganglioglioma with a malignant glial component is classified as WHO grade III. Gangliogliomas and gangliocytomas may occur in all age groups but they are frequently seen in the young with a peak between the age of 10 and 30 years and representing about 0.4% of all tumors in the central nervous system.