This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Bowles, K.M., Vallier, L., Smith, J.R., Alexander, M.R., and Pedersen, R.A. (2006) HOXB4 overexpression promotes hematopoietic development by human embryonic stem cells. Stem Cells, 24(5): 1359–1369.
Cameron, C.M., Hu, W.S., and Kaufman, D.S. (2006) Improved development of human embryonic stem cell-derived embryoid bodies by stirred vessel cultivation. Biotechnol. Bioeng., 17: 1654–7998.
Cerdan, C., Rouleau, A., and Bhatia, M. (2004) VEGF-A165 augments erythropoietic development from human embryonic stem cells. Blood, 103: 2504–2512. Epub 2003 Dec 4.
Chadwick, K. et al. (2003) Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood, 102: 906–915.
Cho, S.K., Bourdeau, A., Letarte, M., and Zuniga-Pflucker, J.C. (2001) Expression and function of CD105 during the onset of hematopoiesis from Flk1(+) precursors. Blood, 98: 3635–3642.
Choi, K., Kennedy, M., Kazarov, A., Papadimitriou, J.C., and Keller, G. (1998) A common precursor for hematopoietic and endothelial cells. Development, 125: 725–732.
Chung, Y.S. et al. (2002) Lineage analysis of the hemangioblast as defined by FLK1 and SCL expression. Development, 129: 5511–5520.
Emambokus, N.R. and Frampton, J. (2003) The glycoprotein IIb molecule is expressed on early murine hematopoietic progenitors and regulates their numbers in sites of hematopoiesis. Immunity, 19: 33–45.
Kaufman, D.S., Hanson, E.T., Lewis, R.L., Auerbach, R., and Thomson, J.A. (2001) Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci. USA, 98: 10716–10721.
Kim, S.J. et al. (2005) Hematopoietic differentiation of embryoid bodies derived from the human embryonic stem cell line SNUhES3 in co-culture with human bone marrow stromal cells. Yonsei Med. J., 46: 693–699.
Mikkola, H.K., Fujiwara, Y., Schlaeger, T.M., Traver, D., and Orkin, S.H. (2003) Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. Blood, 101: 508–516.
Mitjavila-Garcia, M.T. et al. (2002) Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development, 129: 2003–2013.
Narayan, A.D. et al. (2005) Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood, 107: 733.
Ng, E.S., Davis, R.P., Azzola, L., Stanley, E.G., and Elefanty, A.G. (2005) Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation. Blood, 106: 1601–1603.
Nishikawa, S.I., Nishikawa, S., Hirashima, M., Matsuyoshi, N., and Kodama, H. (1998) Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development, 125: 1747–1757.
Oberlin, E., Tavian, M., Blazsek, I., and Peault, B. (2002) Blood-forming potential of vascular endothelium in the human embryo. Development, 129: 4147–4157.
Qiu, C., et al. (2005) Differentiation of human embryonic stem cells into hematopoietic cells by co-culture with human fetal liver cells recapitulates the globin switch that occurs early in development. Exp. Hematol., 33: 1450–1458.
Slukvin, I.I., Vodyanik, M.A., Thomson, J.A., Gumenyuk, M.E., and Choi, K.D. (2006) Directed differentiation of human embryonic stem cells into functional dendritic cells through the myeloid pathway. J. Immunol., 176: 2924–2932.
Tavian, M., Hallais, M.F., and Peault, B. (1999) Emergence of intraembryonic hematopoietic precursors in the pre-liver human embryo. Development, 126: 793–803.
Tavian, M., Robin, C., Coulombel, L., and Peault, B. (2001) The human embryo, but not its yolk sac, generates lympho-myeloid stem cells: mapping multipotent hematopoietic cell fate in intraembryonic mesoderm. Immunity, 15: 487–495.
Tian, X., Morris, J.K., Linehan, J.L., and Kaufman, D.S. (2004) Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells. Exp. Hematol., 32: 1000–1009.
Tian, X., Woll, P.S., Morris, J.K., Linehan, J.L., and Kaufman, D.S. (2006) Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells, 24(5): 1370–1380.
Vodyanik, M.A., Bork, J.A., Thomson, J.A., and Slukvin, I.I. (2005) Human embryonic stem cell-derived CD34+ cells: efficient production in the co-culture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood, 105: 617–626. Epub 2004 Sep 16.
Wang, L. et al. (2004) Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity, 20: 31–41.
Wang, J. et al. (2005a) In vitro hematopoietic differentiation of human embryonic stem cells induced by co-culture with human bone marrow stromal cells and low dose cytokines. Cell Biol. Int., 29: 654–661.
Wang, L. et al. (2005b) Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J. Exp. Med., 201: 1603–1614.
Woll, P.S., Martin, C.H., Miller, J.S., and Kaufman, D.S. (2005) Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity. J. Immunol., 175: 5095–5103.
Zambidis, E.T., Peault, B., Park, T.S., Bunz, F., and Civin, C.I. (2005) Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development. Blood, 106: 860–870. Online April 14, 2005; DOI 10.1182/blood-2004–11-4522.
Zhan, X., et al. (2004) Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet, 364: 163–171.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer
About this chapter
Cite this chapter
Cerdan, C., Ramos-Mejia, V., Bhatia, M. (2007). Hematopoietic Differentiation. In: Masters, J.R., Palsson, B.O., Thomson, J.A. (eds) Human Cell Culture. Human Cell Culture, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5983-4_5
Download citation
DOI: https://doi.org/10.1007/978-1-4020-5983-4_5
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-5982-7
Online ISBN: 978-1-4020-5983-4
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)