Skip to main content

Epigenetics: The Functional Memory of Ribosomal Genes

  • Conference paper
  • 1473 Accesses

Abstract

The functional importance of Epigenetics arise from DNA sequencing programs that show the need for another code to explain the dynamics of gene expression patterns observed along cell differentiation and organism development. In this context, the study of ribosomal gene silencing is in fact an excellent model to better understand the relationships that are established between gene transcription and chromatin topology, and to unravel the epigenetic switches evolved in the framework of gene expression.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   219.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Waddington, C H. “Canalization of development and the inheritance of acquired characters”, Nature, vol. 150, pp. 563–565, 1942.

    Google Scholar 

  2. Miller G, Berlowitz L, Regelson W. “Chromatin and histones in mealy bug cell explants: activation and decondensation of facultative heterochromatin by a synthetic polyanion”, Chromosoma, vol. 32, pp. 251–261, 1971.

    Article  Google Scholar 

  3. Caperta A, Neves N, Morais-Cecílio L, Malhó R, Viegas W. “Genome restructuring in rye affects the expression, organization and disposition of homologous rDNA loci” J. Cell Sci vol. 115, pp. 2839–2846, 2002.

    Google Scholar 

  4. Pontes O, Lawrence RJ, Neves N, Silva M, Lee J-H, Chen ZJ, Viegas W, Pikaard CS “Natural variation in nucleolar dominance reveals the relationship between nucleolus organizer chromatin topology and rRNA gene transcription in Arabidopsis” Proc Natl Acad Sci USA, vol. 100, pp.11418–11423, 2003.

    Article  Google Scholar 

  5. Navashin M. “Chromosomal alterations caused by hybridization and their bearing upon certain general genetic problems” Cytologia, vol. 5, pp. 169–203, 1934.

    Google Scholar 

  6. Viegas W, Neves N, Silva M, Caperta A, Morais-Cecílio L. “Nucleolar dominance: a ‘David and Goliath’ chromatin imprinting process” Curr Genomics, vol. 3, pp. 563–576, 2002.

    Article  Google Scholar 

  7. Castilho A, Queiroz A, Silva M, Barão A, Neves N, Viegas W. “The developmental stage of inactivation of rye origin rRNA genes in the embryo and endosperm of wheat x rye F1 hybrids” Chrom Res, vol. 3, pp. 169–174, 1995.

    Article  Google Scholar 

  8. Silva M, Queiroz A, Neves N, Barão A, Castilho A, Morais-Cecílio L, Viegas W. “Reprogramming of rye rDNA in triticale during microsporogenesis” Chrom Res, vol. 3, 492–496, 1995.

    Article  Google Scholar 

  9. Neves N, Castilho A, Silva M, Heslop-Harrison JS, Viegas W. “Genomic interactions: gene expression, DNA methylation and nuclear architecture” Chrom Today, vol. 12, pp. 182–200, 1997.

    Google Scholar 

  10. Pikaard CS. “The epigenetics of nucleolar dominance” Trends Genet, vol. 16, 495–500, 2000.

    Article  Google Scholar 

  11. Lawrence RJ, Earley K, Pontes O, Silva M, Chen ZJ, Neves N, Viegas W, Pikaard CS. “A concerted DNA methylation/histone methylation switch controlling rRNA gene dosage control and nucleolar dominance” Molecular Cell, vol. 13, 599–609, 2004.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer

About this paper

Cite this paper

Viegas, W.S., Silva, M., Neves, N. (2007). Epigenetics: The Functional Memory of Ribosomal Genes. In: Pereira, M.S. (eds) A Portrait of State-of-the-Art Research at the Technical University of Lisbon. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5690-1_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4020-5690-1_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-1-4020-5689-5

  • Online ISBN: 978-1-4020-5690-1

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics