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Part of the book series: NATO Science Series ((NAII,volume 240))

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Abstract

IVUS is used for diagnostics, therapy guidance and scientific purposes. It is the only clinical available technique that can assess plaque burden and free lumen diameter at high accuracy. Contrast angiography, which was the golden standard before IVUS, can only give a shadow projection of the lumen. Especially with the advent of 3D IVUS using pull backs it became an important tool for monitoring treatment and follow up of interventions like balloon angioplasty and placing of stents (wire prostheses that are used to prevent the arterial wall from recoiling). 3D IVUS in combination with biplane angiography allows assessment of true 3D reconstructions of arteries, pre and post treatment. Using computational fluid dynamics the velocity profile and thus the shear stress at the vascular wall can be calculated. This can be related to biological markers, which gives insight in formation of atherosclerosis, restenosis and remodelling.

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References

  1. Mintz G. S., Popma J. J., Kent K. M., Satler L. F., Wong S. C., Hong M. K.,. Kovach J.A, and Leon M. B., “Arterial remodeling after coronary angioplasty. A serial intravascular ultrasound study,” Circulation, vol. 94, pp. 35–43, 1996.

    Google Scholar 

  2. Bom N, Lancée CT, Van Egmond FC, An ultrasonic intracardiac scanner. Ultrasonics 10: 72 1972.

    Article  Google Scholar 

  3. Bom N, Li W, van der Steen AF, Lancee CT, Cespedes EI, Slager CJ, de Korte CL. Intravascular imaging. Ultrasonics; 36: 625–8 1998.

    Article  Google Scholar 

  4. Ophir J, Cespedes I, Ponnekanti H, et al. Elastography: a quantitative method for imaging the elasticity of biological tissues. Ultrason Imaging; 13: 111–34 1991.

    Article  Google Scholar 

  5. Doyley MM, Mastik F, de Korte CL, et al. Advancing intravascular ultrasonic palpation toward clinical applications. Ultrasound Med Biol; 27: 1471–80 2001.

    Article  Google Scholar 

  6. De Korte CL, Pasterkamp G, van der Steen AF, et al. Characterization of plaque components with intravascular ultrasound elastography in human femoral and coronary arteries in vitro. Circulation; 102: 617–23 2000.

    Google Scholar 

  7. De Korte CL, Carlier SG, Mastik F, et al. Morphological and mechanical information of coronary arteries obtained with intravascular elastography; feasibility study in vivo. Eur Heart J; 23: 405–13 2002.

    Article  Google Scholar 

  8. De Korte CL, Sierevogel MJ, Mastik F, Strijder C, et al. Identification of atherosclerotic plaque components with intravascular ultrasound elastography in vivo: a Yucatan pig study. Circulation; 105: 1627–30 2002.

    Article  Google Scholar 

  9. Casscells W, Hathorn B, David M, et al. Thermal detection of cellular infiltrates in living atherosclerotic plaques: possible implications for plaque rupture and thrombosis. Lancet; 347: 1447–51 1996.

    Article  Google Scholar 

  10. Casscells W, David M, Bearman G et al. Thermography. In: The Vulnerable Atherosclerotic Plaque. Edited by V. Fuster, Futura Publishing Company,: 231–42 1999.

    Google Scholar 

  11. Verheye S, De Meyer GR, Van Langenhove G et al. In vivo temperature heterogeneity of atherosclerotic plaques is determined by plaque composition. Circulation 2002; 105: 1596–601.

    Article  Google Scholar 

  12. Stefanadis C, Diamantopoulos L, Vlachopoulos C et al. Thermal heterogeneity within human atherosclerotic coronary arteries detected in vivo: A new method of detection by application of a special thermography catheter. Circulation; 99:1965–71 1999.

    Google Scholar 

  13. Stefanadis C, Toutouzas K, Tsiamis E, et al. Increased local temperature in human coronary atherosclerotic plaques: an independent predictor of clinical outcome in patients undergoing a percutaneous coronary intervention. J Am Coll Cardiol;37: 1277–83 2001.

    Article  Google Scholar 

  14. Schaar J. A., de Korte C. L., Mastik F., van Damme L. C., Krams R., Serruys P. W., and van der Steen A. F. W., Three-dimensional palpography of human coronary arteries. Herz, 30(2):125–133, 2005.

    Article  Google Scholar 

  15. Goertz D. E., Frijlink M. E., Tempel D., Van Damme L. C. A., Krams R., Schaar J. A., Ten Cate F. J., Serruys P. W., De Jong N. and Van der Steen A. F. W. Invest. Radiol. “Contrast Harmonic Intravascular Ultrasound: a Feasibility Study for Vasa Vasorum Imaging” (in press 2006).

    Google Scholar 

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© 2007 Springer

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DE JONG, N., BOM, N., SCHAAR, J., GOERTZ, D., FRIJLINK, M., STEEN, A.V. (2007). INTRAVASCULAR IMAGING. In: Lemoigne, Y., Caner, A., Rahal, G. (eds) Physics for Medical Imaging Applications. NATO Science Series, vol 240. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5653-6_18

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