Abstract
We live within an ageing population, and those over the age of 85 years will continue to make up increasing numbers and overall total proportion of populations across the world. In the UK, the number of older people aged 85 years and above will more than double in the next 25 years. In 2034, it is predicted that over 3.5 million of the UK population will be aged 85 years or above. This coupled with increasing numbers of older people developing colorectal cancer will result in large numbers of this population presenting to the hospital, either as emergencies or elective admissions for the management of their cancer. While some cancers can be diagnosed and treated in the outpatient setting, a number of tumor types require admission for surgery and for more prolonged chemotherapy and radiotherapy. This is the case in colorectal cancer (CRC). Older patients are at higher risk of adverse effects, including long inpatient stays, increased complications, higher readmission rates, and increased rates of placement in long-term care facilities. In nearly every setting where older people are cared for, a comprehensive geriatric assessment (CGA) is performed. The CGA is defined as “a multi-dimensional, inter disciplinary diagnostic process to determine the medical, psychological and functional capabilities of a frail older person, in order to develop a co-ordinated, integrated plan for treatment and long term follow up.” In general geriatric medicine, CGA is considered to be the gold standard when caring for older people in hospital. There are, however, a number of issues which have not been fully evaluated. These include the following.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Monfardini S, Balducci L. A comprehensive geriatric assessment is necessary for study and the management of cancer in the elderly. Eur J Cancer. 1999;35:1771–2.
Repetto L, Granetto C, Venturino A. Comorbidity and cancer in the aged: the oncologists point of view. Rays. 1997;22:17–9.
Repetto L, Comandini D. Cancer in the elderly: assessing patients for fitness. Crit Rev Oncol Hematol. 2000;35:155–60.
Repetto L, Ausili-Cefaro G, Gallo C, Rossi A, Manzione L. Quality of life in elderly cancer patients. Ann Oncol. 2001;12:S49–52.
Repetto L, Fratino L, Audisio RA, et al. Comprehensive geriatric assessment adds information to Eastern Cooperative Oncology Group Performance status in elderly care patients: an Italian Group for Geriatric Oncology Study. J Clin Oncol. 2002;20:494–502.
Wells JL, Seabrook JA, Stolee P, Borrie MJ, Knoefel F. State of the art in geriatric rehabilitation. Part I: review of frailty and comprehensive geriatric assessment. Arch Phys Med Rehabil. 2003;84(6):890–7.
Baztan JJ, Suarez Garcia FM, Lopez-Arrieta J, Rodriguez-Manas L, Rodriguez-Artalejo F. Effectiveness of acute geriatric units on functional decline, living at home, and case fatality among older patients admitted to hospital for acute medical disorders: meta-analysis. BMJ. 2009;338:b50.
Bernabei R, Venturiero V, Tarsitani P, Gambassi G. The comprehensive geriatric assessment: when, where, how. Crit Rev Oncol Hematol. 2000;33:45–6.
Repetto L, Venturino A, Fratino L, et al. Geriatric oncology: a clinical approach to the older patient with cancer. Eur J Cancer. 2003;39:870–80.
Serraino D, Fratino L, Zagonel V, GIOGer Study Group (Italy). Prevalence of functional disability among elderly patients with cancer. Crit Rev Oncol Hematol. 2001;39:269–73.
Buurman BM, Hoogerduijn JG, De Haan RJ, Abu-Hanna A, et al. Geriatric conditions in acutely hospitalized older patients: prevalence and one-year survival and functional decline. PLoS One. 2011;6:e26951.
Ferrucci L, Guralnik JM, Cavazzini C, Bandinelli S, Lauretani F, Bartali B, et al. The frailty syndrome: a critical issue in geriatric oncology. Crit Rev Oncol Hematol. 2003;46(2):127–37.
Stuck AE, Siu AL, Wieland GD, Adams J, Rubenstein LZ. Comprehensive geriatric assessment: a meta-analysis of controlled trials. Lancet. 1993;342(8878):1032–6.
Baztán JJ, Suárez-García FM, López-Arrieta J, et al. Effectiveness of acute geriatric units on functional decline, living at home, and case fatality among older patients admitted to hospital for acute medical disorders: meta-analysis. BMJ. 2009;338:b50.
Stuck AE, Egger M, Hammer A, et al. Home visits to prevent nursing home admission and functional decline in elderly people. Systematic review and meta-regression analysis. JAMA. 2002;287:1022–8.
Bachmann S, Finger C, Huss A, et al. Inpatient rehabilitation specifically designed for geriatric patients: systematic review and meta-analysis of randomised controlled trials. BMJ. 2010;340:c1718.
Ottenbacher KJ, Smith PM, Illig SB, et al. Trends in length of stay, living setting, functional outcome, and mortality following medical rehabilitation. JAMA. 2004;292:1687–95.
O’Reilly J, Lowson K, Green J, et al. Post-acute care for older people in community hospitals – a cost-effectiveness analysis within a multi-centre randomised controlled trial. Age Ageing. 2008;37:513–20.
Conroy SP, Stevens T, Parker SG, Gladman JRF. A systematic review of comprehensive geriatric assessment to improve outcomes for frail older people being rapidly discharged from acute hospital: ‘interface geriatrics’. Age Ageing. 2011;40:436–43.
Extermann M, Aapro M, Bernabei R, et al. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol. 2005;3:241–52.
Jones DM, Song X, Rockwood K. Operationalizing a frailty index from a standardized comprehensive geriatric assessment. J Am Geriatr Soc. 2004;52:1929–33.
Ferrucci L, Guralnik JM, Cavazzini C, Bandinelli S, et al. The frailty syndrome: a critical issue in geriatric oncology. Crit Rev Oncol Hematol. 2003;46:127–37.
Karnofsky DA. Determining the extent of the cancer and clinical planning for cure. Cancer. 1968;22:730–4.
Barthel DW, Mahoney FI. Functional evaluation: the Barthel Index. Md State Med J. 1965;14:61–5.
Puts MTE, Monette J, Girre V, Wolfson C, et al. Does frailty predict hospitalization, emergency department visits, and visits to the general practitioner in older newly-diagnosed cancer patients? Results of a prospective pilot study. Crit Rev Oncol Hematol. 2010;76:142–51.
Balducci L, Colloca G, Cesari M, Gambassi G. Assessment and treatment of elderly patients with cancer. Surg Oncol. 2010;19:117–23.
Extermann M, Aapro M, Bernabei R, et al. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the international society of geriatric oncology (SIOG). Crit Rev Oncol Hematol. 2005;55:241–2.
Sharkey JR. The interrelationship of nutritional risk factors, indicators of nutritional risk, and severity of disability among home-delivered meal participants. Gerontologist. 2002;42:373–80.
Pallis AG, Fortpied C, Wedding U, Van Nes MC, et al. EORTC elderly task force position paper: approach to the older cancer patient. Eur J Cancer. 2010;46:1502–13.
Overcash JA, Beckstead J, Extermann M, Cobb S. The abbreviated comprehensive geriatric assessment (aCGA): a retrospective analysis. Crit Rev Oncol Hematol. 2005;54:129–36.
Overcash JA, Beckstead J, Moody L, Extermann M, Cobb S. The abbreviated comprehensive geriatric assessment (aCGA) for use in the older cancer patient as a prescreen: scoring and interpretation. Crit Rev Oncol Hematol. 2006;59:205–10.
Reuben DB, Rubenstein LV, Hirsch SH, et al. Value of functional status as a predictor of mortality: results for a prospective study. Medicine. 1992;6:663–9.
Yancik R, Wesley MN, Ries LAG, et al. Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer. 1998;82(11):2123–34.
Balducci L, Stanta S. Cancer in the frail patient: a coming epidemic. Hematol Oncol Clin North Am. 2000;14:235–50.
Guigoz Y, Lauque S, Vellas BJ. Identifying the elderly at risk for malnutrition. The mini nutritional assessment. Clin Geriatr Med. 2002;18:737–57.
Balducci L. New paradigms for treating elderly patients with cancer: the comprehensive geriatric assessment and guidelines for supportive care. J Support Oncol. 2003;1:30–7.
Extermann M. Studies of comprehensive geriatric assessment in patients with cancer. Cancer Control. 2003;10:463–8.
http://www.macmillan.org.uk/Aboutus/Healthprofessionals/Improvingservicesforolderpeople/Pilots/PilotsiteThamesValley.aspx. Accessed on Sept. 9, 2012.
Harari D, Martin FC, Buttery A, et al. The older persons’ assessment and liaison team ‘OPAL’: evaluation of comprehensive and geriatric assessment in acute medical inpatients. Age Ageing. 2007;36:670–5.
Harari D, Hopper A, Jugdeep D, et al. Proactive care for older people undergoing surgery (‘POPS’): designing, embedding, evaluating and funding a comprehensive geriatric assessment service for older elective surgical patients. Age Ageing. 2007;36:190–6.
Puts MTE, Girre V, Wolfson C, et al. Clinical experience of cancer specialists and geriatricians involved in cancer care of older patients: a qualitative study. Crit Rev Oncol Hematol. 2010;74:87–96.
Sifer-Riviere L, Saint-Jeab O, Gisselbrecht M, et al. What the specific tools of geriatrics and oncology can tell us about the role and status of geriatricians in a pilot geriatric oncology program. Ann Oncol. 2011;22:2325–9.
Foster JA, Salinas GD, Mansell SD, et al. How does older age influence oncologists’ cancer management? Oncologist. 2010;15:584–92.
Berzins K, Reilly S, Abell J, et al. UK self-care support initiatives for older patients with long-term conditions: a review. Chronic Illn. 2009;5:56–72.
Zwakhalen SMG, Hamers JPH, Berger MPF. The psychometric quality and clinical usefulness of three pain assessment tools for elderly people with dementia. Pain. 2006;126:210–20.
Gosney MA. Clinical assessment of elderly people with cancer. Lancet Oncol. 2005;6:790–7.
Kristjansson SR, Nesbakken A, et al. Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: a prospective observational cohort study. Crit Rev Oncol Hematol. 2010;76:208–17.
Cheema FN, Abraham NS, Berger DH, et al. Novel approaches to perioperative assessment and intervention may improve long-term outcomes after colorectal cancer resection in older adults. Ann Surg. 2011;253:867–74.
Droz JP, Aapro M, Balducci L. Overcoming challenges associated with chemotherapy treatment in the senior adult population. Crit Rev Oncol Hematol. 2008;68 Suppl 1:S1–8.
Leonard R, Ballinger R, Cameron D, et al. Adjuvant chemotherapy in older women (ACTION) study – what did we learn from the pilot phase? Br J Cancer. 2011;25:1260–6.
Pentheroudakis G, Fiuntzilas G, Kalofonos HP. Palliative chemotherapy in elderly patients with common metastatic malignancies: a Hellenic Cooperative Oncology Group registry analysis of management, outcome and clinical benefit predictors. Crit Rev Oncol Hematol. 2008;66:237–47.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag London
About this chapter
Cite this chapter
Gosney, M.A., Das, P. (2013). Comprehensive Geriatric Assessment. In: Papamichael, D., Audisio, R. (eds) Management of Colorectal Cancers in Older People. Springer, London. https://doi.org/10.1007/978-0-85729-984-0_5
Download citation
DOI: https://doi.org/10.1007/978-0-85729-984-0_5
Published:
Publisher Name: Springer, London
Print ISBN: 978-0-85729-983-3
Online ISBN: 978-0-85729-984-0
eBook Packages: MedicineMedicine (R0)