Abstract
In the early 1980s, the Immunology Unit of King’s College had shown that there were elevated levels of antibodies to the Gram-negative bowel microbe Klebsiella in patients suffering from ankylosing spondylitis.
In 1992, I was attending a Rheumatology Congress in Barcelona when the late Professor Bert Feltkamp from Amsterdam approached me and said: ‘Alan, we have done 3 studies in the Netherlands and we cannot find antibodies in our Dutch ankylosing spondylitis patients as you do in London. It must be the London water’. Clearly, here was a challenge as I knew there was nothing wrong with the London water.
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References
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Ebringer, A. (2011). Dutch Patients with Rheumatoid Arthritis Have Antibodies to Proteus . In: Rheumatoid Arthritis and Proteus. Springer, London. https://doi.org/10.1007/978-0-85729-950-5_7
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DOI: https://doi.org/10.1007/978-0-85729-950-5_7
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