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Lung Cancer

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Side Effects of Medical Cancer Therapy

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Abstract

Lung cancer treatment strategy relies on an accurate staging of the disease and a careful evaluation of patient characteristics, including capability of undergoing and tolerating a defined treatment plan. Therefore, a solid knowledge on all intervention-related adverse events and drug toxicities is essential for a reliable decision-making process.

Most lung cancer patients are diagnosed at an advanced stage of the disease, correlated with a dismal prognosis. Systemic therapy is the mainstay, and drug selection still strongly relies on expected toxicity profile. This chapter first describes the drug standard options and their respective toxicities in this context. Side effects of more complex multimodality combined treatments of early non–small-cell lung cancer as well as small-cell lung cancer, usually involving use of the same cytotoxic agents jointly with surgery and radiotherapy, are discussed in the second part of this chapter.

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Authors and Affiliations

  1. Centre Pluridisciplinaire d’Oncologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

    Stefan Zimmermann M.D.

  2. Department of Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland

    Alessandra Curioni Fontecedro M.D.

  3. Clinic of Oncology, University Hospital Zurich, Ramistrasse 100, Zurich, Switzerland

    Rolf A. Stahel M.D.

  4. Department of Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

    Solange Peters M.D., Ph.D.

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  1. Stefan Zimmermann M.D.
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  2. Alessandra Curioni Fontecedro M.D.
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  3. Rolf A. Stahel M.D.
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  4. Solange Peters M.D., Ph.D.
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Correspondence to Stefan Zimmermann M.D. .

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  1. , Department of Hematology-Oncology, Centre Hospitalier de Luxembourg, Rue Barble 4, Luxembourg, 1210, Luxembourg

    Mario A. Dicato

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Zimmermann, S., Fontecedro, A.C., Stahel, R.A., Peters, S. (2013). Lung Cancer. In: Dicato, M. (eds) Side Effects of Medical Cancer Therapy. Springer, London. https://doi.org/10.1007/978-0-85729-787-7_3

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