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Life-Threatening Autoimmune Hematological Disorders

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Autoimmune Diseases

Abstract

Autoimmune hematological disorders include all conditions in which blood components are attacked by the immune system. The autoimmune cytopenias are a typical example, including: autoimmune thrombocytopenic purpura, autoimmune hemolytic anemia, Evans syndrome, and autoimmune neutropenia. Other autoimmune hematological disorders include acquired thrombotic thrombocytopenic purpura which is linked to the presence of anti-ADAMTS 13 autoantibodies, and acquired hemophilia – due to the presence of anticoagulation factor antibodies. All these conditions are characterized by their acute onset and often need urgent medical attention. This chapter addresses the clinical, diagnostic, and treatment options of hematological autoimmune disorders in the emergency setting.

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Authors and Affiliations

  1. Service de Médecine Interne, Diabète et Maladies Métaboliques, Clinique Médicale B, Hôpital Civil, Hôpitaux Universitaires de Strasbourg, Strasbourg Cedex, France

    Emmanuel Andrès

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  1. Emmanuel Andrès
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  2. Helen Fothergill
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  3. Mustapha Mecili
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Correspondence to Emmanuel Andrès .

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Editors and Affiliations

  1. Rayne Institute, Lupus Research Unit, St. Thomas' Hospital, London, SE1 7EH, United Kingdom

    Munther A. Khamashta

  2. Barcelona, Surgey, Hospital Clinic, Calle Villarroel, 170, Barcelona, 08036, Spain

    Manuel Ramos-Casals

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Andrès, E., Fothergill, H., Mecili, M. (2011). Life-Threatening Autoimmune Hematological Disorders. In: Khamashta, M., Ramos-Casals, M. (eds) Autoimmune Diseases. Springer, London. https://doi.org/10.1007/978-0-85729-358-9_16

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  • DOI: https://doi.org/10.1007/978-0-85729-358-9_16

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