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Plant Metabolic Networks pp 307–322Cite as

Kinetic Properties of Metabolic Networks

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As seen in Chapters 8–10, models of cell metabolism based on steady-state stoichiometric network simulation have been applied successfully to study plant metabolism. However, such models deliver static views of metabolism and do, therefore, not capture the dynamic behavior of metabolic networks. In addition to reaction stoichiometry, kinetic simulation of metabolic networks considers the concentration of metabolites and enzymes, as well as the kinetic properties of enzymes. Kinetic models can be characterized and interrogated, for example, to predict the effect of changes in enzyme activities, in order to identify possible targets for the re-design of metabolism, which is of central importance for biotechnology.

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Notes

  1. 1.

    As opposed to linear pathways, in networks, FCCs can also be negative.

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  1. Brookhaven National Laboratory, Biology Department, Upton, NY 11973, USA

    Jörg Schwender

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    Schwender, J. (2009). Kinetic Properties of Metabolic Networks. In: Schwender, J. (eds) Plant Metabolic Networks. Springer, New York, NY. https://doi.org/10.1007/978-0-387-78745-9_11

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