Age-related macular degeneration (AMD) is the major cause of blindness in the elderly. Vision loss is caused by the death of cone photoreceptor cells in the macula. Approximately 1.65 million Americans over the age of 50 have the disease (Prevent Blindness America). Very little is known about the causes and mechanisms of photoreceptor death in this condition.
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Kanan, Y., Jacobi, A.K., Sawyer, K., Mannel, D.S., Tink, J.T., Al-Ubaidi, M.R. (2008). An in-vivo Assay to Identify Compounds Protective Against Light Induced Apoptosis. In: Anderson, R.E., LaVail, M.M., Hollyfield, J.G. (eds) Recent Advances in Retinal Degeneration. Advances in Experimental Medicine and Biology, vol 613. Springer, New York, NY. https://doi.org/10.1007/978-0-387-74904-4_6
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