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Postoperative Central Nervous System Dysfunction

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Book cover Geriatric Anesthesiology

Abstract

This chapter reviews common forms and causes of central nervous system (CNS) morbidity in the elderly after routine surgery and anesthesia. These include, in order of descending prevalence, delirium, prolonged postoperative cognitive dysfunction (POCD), and perioperative stroke. Although these same conditions are also common during and after cardiac surgery, we will not deal with those situations here because the contributing factors are somewhat different and cognitive morbidity after cardiac surgery is a topic unto itself. We begin with a brief overview of how the brain changes during healthy and pathologic aging because aging of the CNS is a prominent factor in determining susceptibility to cognitive and neurologic morbidity after surgery and anesthesia.

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Authors and Affiliations

  1. Department of Anesthesiology Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Deborah J. Culley MD (Assistant Professor) & Gregory Crosby MD (Associate Professor)

  2. Department of Anesthesiology, Duke University Health System, Durham, NC, USA

    Terri G. Monk MD (Professor)

Authors
  1. Deborah J. Culley MD
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  2. Terri G. Monk MD
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  3. Gregory Crosby MD
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Editor information

Editors and Affiliations

  1. Department of Anesthesiology, Surgery, and Geriatrics and Adult Development , Mount Sinai School of Medicine, New York, NY, USA

    Jeffrey H. Silverstein MD (Professor, Vice Chairman for Research, Associate Dean for Research) (Professor, Vice Chairman for Research, Associate Dean for Research)

  2. Department of Anesthesiology, University of Washington and the Veterans Affairs Puget Sound Health Care System, Seattle, WA

    G. Alec Rooke MD, PhD (Professor and Visiting Professor of Anesthesia, Critical Care, and Pain Medicine) (Professor and Visiting Professor of Anesthesia, Critical Care, and Pain Medicine)

  3. Harvard Medical School Beth Israel Deaconess Medical Center, Boston, MA, USA

    G. Alec Rooke MD, PhD (Professor and Visiting Professor of Anesthesia, Critical Care, and Pain Medicine) (Professor and Visiting Professor of Anesthesia, Critical Care, and Pain Medicine)

  4. College of Medicine Department of Anesthesiology/College of Medicine, Medical University of South Carolina, Charleston, SC, USA

    J. G. Reves MD (Vice President for Medical Affairs, Dean) (Vice President for Medical Affairs, Dean)

  5. Salt Lake City, UT, USA

    Charles H. McLeskey MD

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© 2008 Springer Science+Business Media, LLC

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Culley, D.J., Monk, T.G., Crosby, G. (2008). Postoperative Central Nervous System Dysfunction. In: Silverstein, J.H., Rooke, G.A., Reves, J.G., McLeskey, C.H. (eds) Geriatric Anesthesiology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-72527-7_9

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  • DOI: https://doi.org/10.1007/978-0-387-72527-7_9

  • Publisher Name: Springer, New York, NY

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