Chapter

Monoaminergic Modulation of Cortical Excitability

pp 67-89

Serotonin Modulation of Cortical Activity

  • Pau CeladaAffiliated withDepartment of Neurochemistry and Neuropharmacology, Institut d' Investigacions Biomèdiques de Barcelona (CSIC), IDIBAPS
  • , Francesc ArtigasAffiliated withDepartment of Neurochemistry and Neuropharmacology, Institut d' Investigacions Biomèdiques de Barcelona (CSIC), IDIBAPS

* Final gross prices may vary according to local VAT.

Get Access

Serotonin (5-hydroxytryptamine, 5-HT) is one of the phylogenetically older molecules used in cellular communications. It is present in the central nervous system(CNS) of vertebrate and invertebrate animals, and plays the role of neurotransmitter/neuromodulator. It also operates as a developmental signal in the CNS and regulates a variety of physiological functions in the periphery, such as intestinal motility, platelet aggregation, and vasoconstriction.