Serotonin Modulation of Cortical Activity

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Serotonin (5-hydroxytryptamine, 5-HT) is one of the phylogenetically older molecules used in cellular communications. It is present in the central nervous system(CNS) of vertebrate and invertebrate animals, and plays the role of neurotransmitter/neuromodulator. It also operates as a developmental signal in the CNS and regulates a variety of physiological functions in the periphery, such as intestinal motility, platelet aggregation, and vasoconstriction.