Skip to main content

On the Role and Potential of High-Dimensional Biologic Data in Cancer Research

  • Chapter
  • First Online:
High-Dimensional Data Analysis in Cancer Research
  • 1186 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Amundadottir, L., Sulem, P., Gudmundsson, J., et al. (2006). A common variant associated with prostate cancer in european and african populations. Nature Genetics, 38(6):652–658.

    Article  PubMed  CAS  Google Scholar 

  • Benjamini, Y. and Hochberg, Y. (1995). Controlling for false discovery rate: A practical and powerful approach to multiple testing. Journal of the Royal Statistical Society: Series B, 57:289–300.

    Google Scholar 

  • Druker, B. J., Guilhot, F., O’Brien, S. G., et al. (2006). Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. New England Journal of Medicine, 355(23):2408–2417.

    Article  PubMed  CAS  Google Scholar 

  • Easton, D., Pooley, K., Dunning, A., et al. (2007). Genome-wide association study identifies novel breast cancer susceptibility loci. Nature, 447(7148): 1087–1093.

    Article  PubMed  CAS  Google Scholar 

  • Efron, B. (2004). Large-scale simultaneous hypothesis testing: The choice of a null hypothesis. Journal of the American Statistical Association, 99:96–104.

    Article  Google Scholar 

  • Faca, V., Coram, M., Phanstiel, D., et al. (2006). Quantitative analysis of acrylamide labeled serum proteins by lc-ms/ms. Journal of Proteome Research, 5(8):2009–2018.

    Article  PubMed  CAS  Google Scholar 

  • Felsenstein, J. (2007). Theoretical Evolutionary Genetics. University of Washington/ASUW Publishing, Seattle, WA.

    Google Scholar 

  • Freedman, M. L., Haiman, C. A., Patterson, N., et al. (2006). Admixture mapping identifies 8q24 as a prostate cancer risk locus in african-american men. Proceedings of the National Academy of Sciences, 103(38):14068–14073.

    Article  CAS  Google Scholar 

  • Golub, T. R., Slonim, D. K., Tamayo, P., et al. (1999). Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science, 286(5439):531–537.

    Article  PubMed  CAS  Google Scholar 

  • Hinds, D. A., Stuve, L. L., Nilsen, G. B., et al. (2005). Whole-genome patterns of common DNA variation in three human populations. Science, 307(5712):1072–1079.

    Article  PubMed  CAS  Google Scholar 

  • Hunter, D. J., Kraft, P., Jacobs, K. B., et al. (2007). A genome-wide association study identifies alleles in fgfr2 associated with risk of sporadic postmenopausal breast cancer. Nature Genetics, 39(6):870–874.

    Article  PubMed  CAS  Google Scholar 

  • Khatri, P. and Draghici, S. (2005). Ontological analysis of gene expression data: current tools, limitations, and open problems. Bioinformatics, 18:3587–3595.

    Article  Google Scholar 

  • Ott, J. (1991). Analysis of Human Genetic Linkage. Johns Hopkins University Press, Baltimore, MD.

    Google Scholar 

  • Piccart-Gebhart, M. J., Procter, M., Leyland-Jones, B., et al. (2005). Trastuzumab after adjuvant chemotherapy in her2-positive breast cancer. New England Journal of Medicine, 353(16):1659–1672.

    Article  PubMed  CAS  Google Scholar 

  • Prentice, R. and Qi, L. (2006). Aspects of the design and analysis of high-dimensional snp studies for disease risk estimation. Biostatistics, 7:339–354.

    Article  PubMed  Google Scholar 

  • Rouzier, R., Perou, C. M., Symmans, W. F., et al. (2005). Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clinical Cancer Research, 11(16):5678–5685.

    Article  PubMed  CAS  Google Scholar 

  • Ruczinski, I., Kooperberg, C., and LeBlanc, M. (2003). Logic regression. Journal of Computational and Graphical Statististics, 12:475–511.

    Article  Google Scholar 

  • Samani, N. J., Erdmann, J., Hall, A. S., et al. (2007). Genomewide association analysis of coronary artery disease. New England Journal of Medicine, 357(5):443–453.

    Article  PubMed  CAS  Google Scholar 

  • Shurubor, Y., Matson, W., Martin, R., et al. (2005). Relative contribution of specific sources of systematic errors and analytic imprecision to metabolite analysis by hplc-ecd. Metabolomics, 1:159–168.

    Article  CAS  Google Scholar 

  • The International HapMap Consortium (2003). The international hapmap project. Nature, 426(6968):789–796.

    Google Scholar 

  • The Women's Health Initiative Steering Committee (2004). Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The women's health initiative randomized controlled trial. JAMA, 291(14):1701–1712.

    Google Scholar 

  • Thomas, D. (2004). Statistical Methods in Genetic Epidemiology. Oxford University Press, London.

    Google Scholar 

  • Tibshirani, R. (1996). Regression shrinkage and selection via the lasso. Journal of the Royal Statistical Society B, 58:267–288.

    Google Scholar 

  • Wang, X., Yu, J., Sreekumar, A., et al. (2005). Autoantibody signatures in prostate cancer. New England Journal of Medicine, 353(12):1224–1235.

    Article  PubMed  CAS  Google Scholar 

  • Writing Group for the Women's Health Initiative Investigators (2002). Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the women's health initiative randomized controlled trial. Journal of the American Medical Association, 288(3):321–333.

    Google Scholar 

  • Yeager, M., N., O., Hayes, R. B., et al. (2007). Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nature Genetics, 39(5):645–649.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ross L. Prentice .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Prentice, R.L. (2009). On the Role and Potential of High-Dimensional Biologic Data in Cancer Research. In: Li, X., Xu, R. (eds) High-Dimensional Data Analysis in Cancer Research. Applied Bioinformatics and Biostatistics in Cancer Research. Springer, New York, NY. https://doi.org/10.1007/978-0-387-69765-9_1

Download citation

Publish with us

Policies and ethics