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Immune-Compromised Patients: Human Immunodeficiency Virus and Organ Transplantation

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Handbook of Consultation-Liaison Psychiatry

The consultation-liaison psychiatrist (CL) has no greater opportunity and obligation to contribute to patient care, practitioner training, and research than in advancing the work with immune-compromised patients. This area of health care has grown enormously in the past quarter century with the global emergence of the acquired immune deficiency syndrome (AIDS) epidemic. New case numbers continue to rise in the established geography of the disease, and AIDS continues to enter areas heretofore untouched by the condition. Current projections suggest that by the year 2030, AIDS will take more lives than were lost in any of the other great plagues of humanity (UNAIDS, 2006).

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References

  • Aldridge D. Hope, meaning and the creative arts therapies in the treatment of AIDS. Arts in Psychotherapy 1993;20:285–297.

    Article  Google Scholar 

  • Angelino AF, Treisman GJ. Management of psychiatric disorders in patients infected with human immunodeficiency virus. Clin Infect Dis 2001;33:847–856.

    Article  PubMed  CAS  Google Scholar 

  • Baines LS, Joseph JT, Jindal RM. Prospective randomized study of individual and group psychotherapy versus controls in recipients of renal transplants. Kidney Int 2004;65(5):1937–1942.

    Article  PubMed  Google Scholar 

  • Bellamy CO, et al. Liver transplantation for alcoholic cirrhosis: long term follow-up and impact of disease recurrence. Transplantation 2001;72(4):619–626.

    Article  PubMed  CAS  Google Scholar 

  • Beresford TP, Martin B, Alfers J. Developing a brief monitoring procedure for alcohol-dependent liver graft recipients. Psychosomatics 2004;45(3):220–223.

    Article  PubMed  Google Scholar 

  • Borlongan CV, Fujisaki T, Watanabe S. Chronic administration of cyclosporine A does not impair memory retention in rats. Neuroreport 1997;8(3):673–676.

    Article  PubMed  CAS  Google Scholar 

  • Breitbart W, Marotta R, Platt MM, et al. A double-blind trial of haloperidol, chlorpromazine, and lorazepam in the treatment of delirium in hospitalized AIDS patients. Am J Psychiatry 1996;153(2):231–237.

    PubMed  CAS  Google Scholar 

  • Cerullo M. Corticosteroid induced mania: prepare for the unpredictable. Current Psychiatry 2006;5(6):43–50.

    Google Scholar 

  • Chegounchi M, Hanna MG, Neild GH. Progressive neurological disease induced by tacrolimus in a renal transplant recipient: case presentation. BMC Nephrol 2006;7:7.

    Article  PubMed  Google Scholar 

  • Chisholm MA. Issues of adherence to immunosuppressant therapy after solid-organ transplantation. Drugs 2002;62(4):567–575.

    Article  PubMed  Google Scholar 

  • Ciancio G, et al. A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year. Transplantation 2004;77(2):252–258.

    Article  PubMed  CAS  Google Scholar 

  • Clarke DM, Kissane DW. Demoralization: its phenomenology and importance. Aust NZ J Psychiatry 2002;36:733–742.

    Article  Google Scholar 

  • Cohen MAA. Biopsychosocial approach to the human immunodeficiency virus epidemic a clinician’s primer. Gen Hospl Psychiatry 1990;12:98–123.

    Article  CAS  Google Scholar 

  • Crawford DJ, et al. Rational design of novel immunosuppressive drugs: analogues of azathioprine lacking the 6–mercaptopurine substituent retain or have enhanced immunosuppressive effects. J Med Chem 1996;39(14):2690–2695.

    Article  PubMed  CAS  Google Scholar 

  • Cruess DG, Evans DL, Repetto MJ, et al. Prevalence, diagnosis, and pharmacological treatment of mood disorders in HIV disease. Biol Psychiatry 2003;54:307–316.

    Article  PubMed  Google Scholar 

  • Cupples SA, Stilley CS. Cognitive function in adult cardiothoracic transplant candidates and recipients. J Cardiovasc Nurs 2005;20(5 suppl):S74–87.

    PubMed  Google Scholar 

  • De Groen PC, et al. Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol. N Engl J Med 1987;317(14):861–866.

    PubMed  Google Scholar 

  • DeSilva KE, Le Flore DB, Marston BJ, Rimland D. Serotonin syndrome in HIV-infected individuals receiving antiretroviral therapy and fluoxetine. AIDS 2001;15:1281–1285.

    Article  PubMed  CAS  Google Scholar 

  • Dettling M, Muller-Oerlinghausen B, Britsch P. Clozapine treatment of HIV-associated psychosis—too much bone marrow toxicity? Pharmacopsychiatry 1998;31:156–157.

    Article  PubMed  CAS  Google Scholar 

  • Dew MA, et al. Prevalence and predictors of depression and anxiety-related disorders during the year after heart transplantation. Gen Hosp Psychiatry 1996;18(6 suppl):48S–61S.

    Article  PubMed  CAS  Google Scholar 

  • DiMartini A, Weinrieb R, Fireman M. Liver transplantation in patients with alcohol and other substance use disorders. Psychiatr Clin North Am 2002;25(1):195–209.

    Article  PubMed  Google Scholar 

  • DiMartini A, et al. Alcohol consumption patterns and predictors of use following liver transplantation for alcoholic liver disease. Liver Transpl 2006;12(5):813–820.

    Article  PubMed  Google Scholar 

  • DiMartini A, et al. Tobacco use following liver transplantation for alcoholic liver disease: an underestimated problem. Liver Transpl 2005;11(6):679–683.

    Article  PubMed  Google Scholar 

  • Dore GJ, Correll PK, Li Y, Kaldor JM, Cooper DA, Brew BJ. Changes to AIDS dementia complex in the era of highly active antiretroviral therapy. AIDS 1999;13(10):1249–1253.

    Article  PubMed  CAS  Google Scholar 

  • Edwards GM. Art therapy with HIV-positive patients: hardiness, creativity and meaning. Arts in Psychotherapy 1993;20:325–333.

    Article  Google Scholar 

  • Eisenberg L. The physician as interpreter: ascribing meaning to the illness experience. Comprehensive Psychiatry 1981;22:239–248.

    Article  PubMed  CAS  Google Scholar 

  • Elliot AJ, Roy-Byrne PP. The effect of changes in depression on health related quality of life in HIV infection. Gen Hosp Psychiatry 2002;24:43–47.

    Article  Google Scholar 

  • Farber EW, Mirsalimi H, Williams KA, McDaniel JS. Meaning of illness and psychological adjustment. Psychosomatics 2003;44(6):485–491.

    Article  PubMed  Google Scholar 

  • Farber EW, Schwartz JAJ, Schaper PE, Moonen DJ, McDaniel JS. Resilience factors associated with adaptation to HIV disease. Psychosomatics 2000;41(2):140–146.

    Article  PubMed  CAS  Google Scholar 

  • Ferrando SJ, Wapenyi K. Psychopharmacological treatment of patients with HIV and AIDS. Psychiatr Q 2002;73(1):33–49.

    Article  PubMed  Google Scholar 

  • Garro LC, Mattingly C. Narrative as construct and construction. In: Garro LC, Mattingly C, eds. Narrative and the Cultural Construction of Illness and Healing. Berkeley: University of California Press, 2000.

    Google Scholar 

  • Glaser R. Stress-associated immune dysregulation and its importance for human health: a personal history of psychoneuroimmunology. Brain, Behav Immun 2005;19:3–11.

    Article  Google Scholar 

  • Gross CR, et al. Mindfulness meditation to reduce symptoms after organ transplant: a pilot study. Adv Mind Body Med 2004;20(2):20–29.

    PubMed  Google Scholar 

  • Hathaway D, et al. The first report from the patient outcomes registry for transplant effects on life (PORTEL): differences in side-effects and quality of life by organ type, time since transplant and immunosuppressive regimens. Clin Transplant 2003;17(3):183–194.

    Article  PubMed  Google Scholar 

  • Hathaway DK, et al. Quality of life outcomes associated with variable posttransplant prednisone dosing regimens. J Transpl Coord 1996;6(2):64–68.

    PubMed  CAS  Google Scholar 

  • Hotson JR, Enzmann DR. Neurologic complications of cardiac transplantation. Neurol Clin 1988;6(2):349–365.

    PubMed  CAS  Google Scholar 

  • Kanchana TP, et al. Liver transplantation for patients on methadone maintenance. Liver Transpl 2002;8(9):778–782.

    Article  PubMed  Google Scholar 

  • Kasner SE, et al. Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients. Neurology 2005;65(2):337–338; author reply 337–338.

    PubMed  CAS  Google Scholar 

  • Kelly M, et al. Predictors of relapse to harmful alcohol after orthotopic liver transplantation. Alcohol Alcohol 2006;41(3):278–283.

    PubMed  Google Scholar 

  • Koch M, Banys P. Liver transplantation and opioid dependence. JAMA 2001;285(8):1056–1058.

    Article  PubMed  CAS  Google Scholar 

  • Koch M, Banys P. Methadone is a medication, not an addiction. Liver Transpl 2002;8(9):783–786.

    Article  PubMed  Google Scholar 

  • Kreitzer MJ, et al. Longitudinal impact of mindfulness meditation on illness burden in solid-organ transplant recipients. Prog Transplant 2005;15(2):166–172.

    PubMed  Google Scholar 

  • Lera G, Zirulnik J. Pilot study with clozapine in patients with HIV-associated psychosis and drug-induced Parkinsonism. Mov Disord 1999;14:128–131.

    Article  PubMed  CAS  Google Scholar 

  • Levenson JL, Olbrisch ME. Psychosocial evaluation of organ transplant candidates. A comparative survey of process, criteria, and outcomes in heart, liver, and kidney transplantation. Psychosomatics 1993;34(4):314–323.

    PubMed  CAS  Google Scholar 

  • Limbos MM, et al. Psychological functioning and quality of life in lung transplant candidates and recipients. Chest 2000;118(2):408–416.

    Article  PubMed  CAS  Google Scholar 

  • Lisson GL, et al. A brief psychological intervention to improve adherence following transplantation. Ann Transplant 2005;10(1):52–57.

    PubMed  Google Scholar 

  • Liu LU, et al. Survival and risk of recidivism in methadone-dependent patients undergoing liver transplantation. Am J Transplant 2003;3(10):1273–1277.

    Article  PubMed  Google Scholar 

  • Lyketsos CG, Hanson A, Fishman M, McHugh PR, Treisman GJ. Screening for psychiatric morbidity in a medical outpatient clinic for HIV infection: the need for psychiatric presence. Int J Psychiatry Med 1994;24:103–113.

    PubMed  CAS  Google Scholar 

  • Maggi JD, Halman MH. The effect of divalproex sodium on viral load: a retrospective review of HIV-positive patients with manic syndromes. Can J Psychiatry 2001;46:359–362.

    PubMed  CAS  Google Scholar 

  • Markowitz JC, Kocsis JH, Fishman B, et al. Treatment of depressive symptoms in human immunodeficiency virus-positive patients. Arch Gen Psychiatry 1998;55:452–457.

    Article  PubMed  CAS  Google Scholar 

  • Mehra MR, et al. Recrudescent tobacco exposure following heart transplantation: clinical profiles and relationship with athero-thrombosis risk markers. Am J Transplant 2005;5(5):1137–1140.

    Article  PubMed  Google Scholar 

  • Munoz R, et al. Cyclosporine-associated leukoencephalopathy in organ transplant recipients: experience of three clinical cases. Transplant Proc 2006;38(3):921–923.

    Article  PubMed  CAS  Google Scholar 

  • Nelson CJ, Rosenfield B, Breitbart W, Galietta M. Spirituality, religion, and depression in the terminally ill. Psychosomatics 2002;43(3):213–220.

    Article  PubMed  Google Scholar 

  • Olbrisch ME, Levenson JL. Psychosocial assessment of organ transplant candidates. Current status of methodological and philosophical issues. Psychosomatics 1995;36(3):236–243.

    PubMed  CAS  Google Scholar 

  • Perez-San-Gregorio MA, et al. Psychologic stages in renal transplant. Transplant Proc 2005;37(3):1449–1452.

    Article  PubMed  CAS  Google Scholar 

  • Perkins DO, Davidson EJ, Lesserman J, et al. Personality disorder in patients infected with HIV: a controlled study with implications for clinical care. Am J Psychiatry 1993;150:309–315.

    PubMed  CAS  Google Scholar 

  • Petersen S, Bull C, Propst O, Dettinger S, et al. Narrative therapy to prevent illness-related stress disorder. J Counsel Dev 2005;83:41–47.

    Google Scholar 

  • Prasad GV, et al. Renal transplant recipient attitudes toward steroid use and steroid withdrawal. Clin Transplant 2003;17(2):135–139.

    Article  PubMed  Google Scholar 

  • Rodriguez JR, et al. A randomized evaluation of quality-of-life therapy with patients awaiting lung transplantation. Am J Transplant 2005;5(10):2425–2432.

    Article  Google Scholar 

  • Safren SA, Otto MW, Worth J, et al. Two strategies to increase adherence to HIV antiretroviral medication: life-steps and medication monitoring. Behav Res Ther 2001;39:1151–1162.

    Article  PubMed  CAS  Google Scholar 

  • Safren SA, Radomsky AS, Otto MW, Salamon E. Predictors of psychological well-being in a diverse sample of HIV-positive patients receiving highly active antiretroviral therapy. Psychosomatics 2002;43(6):478–485.

    Article  PubMed  Google Scholar 

  • Schifitto G, Peterson DR, Zhong J, et al. Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report. Neurology 2006;66(6): 919–921.

    Article  PubMed  CAS  Google Scholar 

  • Sewell M, Goggin K, Ferrando SJ, et al. Anxiety among men with AIDS: a longitudinal controlled study. Psychosomatics 2000;4:294–300.

    Article  Google Scholar 

  • Sheridan K, Sheridan EP. Psychological consultation to persons with AIDS. Professional Psychol Res Pract 1988;19(5):532–535.

    Article  Google Scholar 

  • Shitrit D, et al. Progressive multifocal leukoencephalopathy in transplant recipients. Transpl Int 2005;17(11):658–665.

    Article  PubMed  Google Scholar 

  • Singh AN, Golledge H, Catalan J. Treatment of HIV-related psychotic disorders with risperidone: a series of 21 cases. J Psychosom Res 1997;42:489–493.

    Article  PubMed  CAS  Google Scholar 

  • Singh K, Ochitill H. Personality disorders. In: Fernandez F, Ruiz P, eds. Psychiatric Aspects of HIV/AIDS. Philadelphia: Lippincott Williams & Wilkins, 2006.

    Google Scholar 

  • Singh N, Squier C, Sivek C, Wagener M, Nguyen MH, Yu VL. Determinants of compliance with antiretroviral therapy in patients with human immunodeficiency virus: prospective assessment with implications for enhancing compliance. AIDS Care 1996;8:261–269.

    Article  PubMed  CAS  Google Scholar 

  • Slavney PR. Diagnosing demoralization in consultation psychiatry. Psychosomatics 1999;40(4):325–329.

    PubMed  CAS  Google Scholar 

  • Sorrell JH, et al. Cognitive impairment in people diagnosed with end-stage liver disease evaluated for liver transplantation. Psychiatry Clin Neurosci 2006;60(2):174–181.

    Article  PubMed  Google Scholar 

  • Southworth MR, Dunlap SH. Psychotic symptoms and confusion associated with intravenous ganciclovir in a heart transplant recipient. Pharmacotherapy 2000;20(4):479–483.

    Article  PubMed  CAS  Google Scholar 

  • Tanriverdi N, et al. Quality of life and mood in renal transplantation recipients, donors, and controls: preliminary report. Transplant Proc 2004;36(1):117–119.

    Article  PubMed  CAS  Google Scholar 

  • Trzepacz PT, DiMartini A, Tringali R. Psychopharmacologic issues in organ transplantation. Part 1: Pharmacokinetics in organ failure and psychiatric aspects of immunosuppressants and anti-infectious agents. Psychosomatics 1993a;34(3):199–207.

    PubMed  CAS  Google Scholar 

  • Trzepacz PT, DiMartini A, Tringali RD. Psychopharmacologic issues in organ transplantation. Part 2: Psychopharmacologic medications. Psychosomatics 1993b;34(4):290–298.

    PubMed  CAS  Google Scholar 

  • Trzepacz PT, Levenson JL, Tringali RA. Psychopharmacology and neuropsychiatric syndromes in organ transplantation. Gen Hosp Psychiatry 1991;13(4):233–245.

    Article  PubMed  CAS  Google Scholar 

  • UNAIDS. Report on the Global AIDS Epidemic. New York: United Nations, 2006.

    Google Scholar 

  • Vella JP, Sayegh MH. Interactions between cyclosporine and newer antidepressant medications. Am J Kidney Dis 1998;31(2):320–323.

    Article  PubMed  CAS  Google Scholar 

  • Viswanathan R, Glickman L. Clonazepam in the treatment of steroid-induced mania in a patient after renal transplantation. N Engl J Med 1989;320(5):319–320.

    Article  PubMed  CAS  Google Scholar 

  • Wallace J, et al. The use of art therapy to detect depression and post-traumatic stress disorder in pediatric and young adult renal transplant recipients. Pediatr Transplant 2004;8(1):52–59.

    Article  PubMed  Google Scholar 

  • Weinrieb RM, et al. A matched comparison study of medical and psychiatric complications and anesthesia and analgesia requirements in methadone-maintained liver transplant recipients. Liver Transpl 2004;10(1):97–106.

    Article  PubMed  Google Scholar 

  • Work Group on HIV/AIDS. Practice guidelines for the treatment of patients with HIV/AIDS. Am J Psychiatry 2000;157:11.

    Google Scholar 

  • Zilikis N, Nimatoudis I, Kiosses V, et al. Treatment with risperidone of an acute psychotic episode in a patient with AIDS. Gen Hosp Psychiatry 1998;20:384–385.

    Article  PubMed  CAS  Google Scholar 

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Singh, K., Skotzko, C., Ochitill, H. (2007). Immune-Compromised Patients: Human Immunodeficiency Virus and Organ Transplantation. In: Handbook of Consultation-Liaison Psychiatry. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-69255-5_20

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  • DOI: https://doi.org/10.1007/978-0-387-69255-5_20

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