Optical coherence tomography (OCT) is a new type of medical diagnostic imaging modality that performs high-resolution, micron-scale, cross-sectional tomography imaging of ocular structures in vitro and in vivo.1 Researchers at Harvard, the Massachusetts Institute of Technology, and Tufts University developed this technology. The first commercial device for use in posterior segment structures became available in 1995 (Humphrey Instruments, Dublin, CA). The OCT image has an axial resolution of 10 μm, and this resolution is significantly higher than those achieved by the scanning laser ophthalmoscope, B-scan ultrasound, and ultrasound biomicroscopy (UBM), which have image resolutions of 300, 150, and 20 μm, respectively.2
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References
Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science 1991;254:1178–1181.
Pavlin CJ, Harasiewicz K, Sherar MD, Foster FS. Clinical use of ultrasound biomicroscopy. Ophthalmology 1991;98:287–295.
Laser Institute of America. American National Standard for the Safe Use of Lasers. Toledo, OH: Laser Institute of America, 1986.
Hee MR, Puliafito CA, Wong C, et al. Optical coherence tomography of macular holes. Ophthalmology 1995;102:748–756.
Puliafito CA, Hee MR, Lin CP, et al. Imaging of macular diseases with optical coherence tomography. Ophthalmology 1995;102:217–229.
Puliafito CA, Hee MR, Schuman JS, Fujimoto JG. Optical Coherence Tomography of Ocular Diseases, 1st ed. Thorofare, NJ: Slack, 1996.
Hee MR, Puliafito CA, Wong C, et al. Quantitative assessment of macular edema with optical coherence tomography. Arch Ophthalmol 1995;113:1019–1029.
Hee MR, Izatt JA, Swanson EA, et al. Optical coherence tomography of the human retina. Arch Ophthalmol 1995;113:325–332.
Baumann M, Gentile RC, Liebmann JM, Ritch R. Reproducibility of retinal thickness measurements in normal eyes using optical coherence tomography. Ophthalmic Surg Lasers 1998;29:280–285.
Toth CA, Narayan DG, Boppart SA, et al. A comparison of retinal morphology viewed by optical coherence tomography and by light microscopy. Arch Ophthalmol 1997;115:1425–1428.
Munuera JM, Garcia-Layana A, Maldonado MJ, Aliseda D, Moreno-Montanes J. Optical coherence tomography in successful surgery of vitreomacular traction syndrome. Arch Ophthalmol 1998;116:1388–1389.
Wilkins JR, Puliafito CA, Hee MR, et al. Characterization of epiretinal membranes using optical coherence tomography. Ophthalmology 1996;103:2142–2151.
Gass JD. Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 1995;119:752–759.
Gass JD, Joondeph BC. Observations concerning patients with suspected impending macular holes. Am J Ophthalmol 1990;109:638–646.
Gass JD. Idiopathic senile macular hole. Its early stages and pathogenesis. Arch Ophthalmol 1988;106:629–639.
Duker JS, Puliafito CA, Wilkins JR, et al. Imaging fellow eyes in patients diagnosed with idiopathic macularholes using optical coherence tomography (OCT). Ophthalmology 1995;102(suppl):118.
Ip M, Garza-Karren C, Duker JS, et al. Differentiation of degenerative retinoschisis from retinal detachment using optical coherence tomography. Ophthalmology 1999;06:600–605.
Hee MR, Puliafito CA, Duker JS, et al. Topography of diabetic macular edema with optical coherence tomography. Ophthalmology 1998;105:360–370.
Hee MR, Puliafito CA, Wong C, et al. Optical coherence tomography of central serous chorioretinopathy. Am J Ophthalmol 1995;120:65–74.
Montera JM, Ruiz-Moreno JM. Optical coherence tomography characterization of idiopathic central serous chorioretinopathy. Br J Ophthalmol 2005;89:562–564.
Wang M, Sander B, Lund Anderson H, Larsen M. Detection of shallow detachments in central serous Chorioretinopathy. Acta Ophthalmol Scand 1999;77:402–405.
Hee MR, Baumal CR, Puliafito CA, et al. Optical coherence tomography of age-related macular degeneration and choroidal neovascularization. Ophthalmology 1996;103:1260–1270.
Toth CA, Birngruber R, Boppart SA, et al. Argon laser retinal lesions evaluated in vivo by optical coherence tomography. Am J Ophthalmol 1997;123:188–198.
Baumal CR, Puliafito CA, Pierrot L, et al. Photodynamic therapy (PDT) of experimental choroidal neovascularization with tin ethyl etiopurpurin (SnET2). Invest Ophthalmol Vis Sci 1996;suppl 37:S122.
Rogers AH, Martidis A, Greenberg PB, Puliafito CA. Optical coherence tomography findings following photodynamic therapy of choroidal neovascularization. Am J Ophthalmol 2002;134:566–576.
Schuman JS, Puliafito CA, Fujimoto JG. Optical Coherence Tomography of Ocular Diseases, 2nd ed. Thorofare, NJ: Slack, 2004.
Spaide RF, Lee JK, Klancnik JM, Gross NE. Optical coherence tomography of branch retinal vein occlusion. Retina 2003;23:343–347.
Greenberg PB, Martidis A, Rogers AH, Duker JS, Reichel E. Intravitreal triamcinolone acetonide as treatment of macular edema due to central retinal vein occlusion. Br J Ophthalmol 2002;86(2):247–248.
Martinez-Jardon CS, Meza-de Regil A, Dalma-Weiszhausz J, et al. Radial optic neurotomy for ischaemic central vein occlusion. Br J Opthalmol 2005;89:558–561.
Gass JDM. Stereoscopic Atlas of Macular Diseases, 4th ed. St. Louis: CV Mosby, 1997:374–376.
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Arevalo, J.F., Mendoza, A.J., Fernandez, C.F., Sanchez, J.G., Reinaldo, A. (2009). Clinical Applications of Optical Coherence Tomography in Macular Diseases. In: Arevalo, J.F. (eds) Retinal Angiography and Optical Coherence Tomography. Springer, New York, NY. https://doi.org/10.1007/978-0-387-68987-6_11
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