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Molecular Sensors for Cardiovascular Homeostasis pp 171–188Cite as

Redox Signaling in Oxygen Sensing by Vessels

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Abstract

Oxidant production and regulation is becoming increasingly important in the study of vascular signaling mechanism.Alarge number of studies during the last 50 years have provided evidence that vascular preparations show alterations in contractile function over a wide range of O2 tensions that are observed in physiological systems. Based on observations that reactive oxygen species were vasoactive and appeared to have distinct signaling mechanisms, itwas suggested that these species could function in vascular O2 sensing mechanisms that mediated responses to acute changes in pO2.1,2

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  1. Andrea Olschewski
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  2. E. Kenneth Weir
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  1. Department of Medicine, Neuroscience, and Cell and Molecular Biology Program, Michigan State University, East Lansing, MI, 48824–1313, USA

    Donna H. Wang

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Olschewski, A., Weir, E.K. (2007). Redox Signaling in Oxygen Sensing by Vessels. In: Wang, D.H. (eds) Molecular Sensors for Cardiovascular Homeostasis. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-47530-1_10

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