Abstract
Primary thymic epithelial neoplasms represent the most common type of tumors of the anterior mediastinum. These tumors have been a source of major controversy over the years, due to the difficulty of their histopathologic typing and their often unpredictable biologic behavior. Unlike malignant epithelial neoplasms arising in other organs, for many years it was thought that these tumors were unsuitable for histologic grading. In fact, the latest World Health Organization schema for the classification of thymic epithelial neoplasms does not even mention grading for these tumors.
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References
Books and monographs
Rosai J. World Health Organization International Histological Classification of Tumors: Histological Typing of Tumors of the Thymus. 2nd edition. Berlin: Springer; 1999.
Weidner N, Cote RJ, Suster S, Weiss LM, eds. Modern Surgical Pathology. Philadelphia: Saunders, Elsevier; 2003.
Articles
Suster S, Moran CA. Primary thymic epithelial neoplasms with combined features of thymoma and thymic carcinoma. A clinicopathologic study of 22 cases. Am J Surg Pathol. 1996;20:1469–1480.
Suster S, Moran CA. Thymoma, atypical thymoma, and thymic carcinoma. A novel conceptual approach to the classification of neoplasms of thymic epithelium. Am J Clin. Pathol. 1999;111:826–833.
Suster S, Moran CA. Primary thymic epithelial neoplasms. Spectrum of differentiation and histologic features. Semin. Diagn Pathol. 1999;16:2–17.
Suster S, Rosai J. Thymic carcinoma. A clinicopathologic study of 60 cases. Cancer. 1991;67:1025–1032.
Suster S, Moran CA. Thymic carcinoma: spectrum of differentiation and histologic types. Pathology. 1998;30:111–122.
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© 2007 Springer Science+Business Media, LLC
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Suster, S., Moran, C. (2007). Tumors of the Thymus. In: Damjanov, I., Fan, F. (eds) Cancer Grading Manual. Springer, New York, NY. https://doi.org/10.1007/978-0-387-33751-7_6
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DOI: https://doi.org/10.1007/978-0-387-33751-7_6
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-33750-0
Online ISBN: 978-0-387-33751-7
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