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Most reports on the case, however, fail to illustrate the profound behavioral and affective changes that took place following the accident and practically destroyed Gage’s life. A very illuminating study, complete with computerized reconstructions of the putative damage, can be found in Damasio (1994, pp. 3–33).
Another comprehensive “emergentist” neural model forms the subject of Scott’s Neuroscience (2002).
“Up to 70% of cells in a given area (of the nervous system) may die before the tissue is shaped” (Edelman, 1988, p. 13).
Interestingly, when the synaptic network is stimulated by electrodes, the majority of synapses shows no detectable activity, these are called silent synapses. The silence, however, does not connote synaptic failure but rather selectional events occurring over the entire population of synapses in the region (Edelman, 1988, p. 207).
For a detailed review of this fundamental process see Edelman (1989, pp. 64–90).
Damasio (1999) notes: “The investigation of patients with neurological disease has shaped my view on consciousness more than any other source of evidence” (p. 86).
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(2007). The Language of the Objective Observer: Gerald Edelman and Neurodarwinism: Antonio Damasio and the Feeling of Knowing. In: The Rosetta Stone of the Human Mind. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-33645-9_4
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DOI: https://doi.org/10.1007/978-0-387-33645-9_4
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