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Disorders of Phosphorous Homeostasis in CKD

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Book cover Calcium and Phosphate Metabolism Management in Chronic Renal Disease

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XI. Conclusions

Pi is a key ion in the body, with important diverse functions. The maintenance of serum Pi levels is dependent on normal kidney function. As a result, patients with kidney disease are often hyperphosphatemic. Elevations in serum Pi are associated with increased morbidity and mortality in patients with CKD, may hasten loss of residual renal function, and can cause secondary hyperparathyroidism. Unfortunately, current removal of Pi with thrice weekly hemodialysis or daily peritoneal dialysis is not adequate for normal dietary intake. As a result, phosphate binders are a mainstay of therapy in patients with CKD.

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Authors and Affiliations

  1. Department of Internal Medicine, Nephrology Division, Indiana University School of Medicine, Indianapolis, IN

    Sharon M. Moe MD

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  1. Sharon M. Moe MD
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Editors and Affiliations

  1. Medical Center, The University of Michigan, Ann Arbor, Michigan, USA

    Chen Hsing Hsu MD (Professor of Internal Medicine) (Professor of Internal Medicine)

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Moe, S.M. (2006). Disorders of Phosphorous Homeostasis in CKD. In: Hsu, C.H. (eds) Calcium and Phosphate Metabolism Management in Chronic Renal Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-33370-0_2

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  • DOI: https://doi.org/10.1007/978-0-387-33370-0_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-33369-4

  • Online ISBN: 978-0-387-33370-0

  • eBook Packages: MedicineMedicine (R0)

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