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Leptin in Farm Animals

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Leptin

Part of the book series: Endocrine Updates ((ENDO,volume 25))

Abstract:

The Recently discovered protein, leptin, which is secreted by fat cells, has been implicated in regulation of feed intake, energy balance and the neuroendocrine axis in rodents, humans and large domestic animals. The leptin receptor which has been cloned and is a member of the class 1 cytokine family of receptors is found in the brain and pituitary and numerous peripheral tissues. The interaction of leptin in energy metabolism, feed intake regulation, growth and immune function in domestic animals is reviewed. Preadipocyte recruitment and subsequent fat cell size and leptin gene expression are regulated by such hormones as insulin and cortisol and its interactions. Leptin serves as a metabolic signalthat acts on the hypothalamic-pituitary-ovarian axis to enhance GnRH and LH secretion and ovarian function.

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Authors and Affiliations

  1. Animal Physiology Research Unit, USDA-ARS, Athens, GA, USA

    C. Richard Barb & Gary J. Hausman

  2. Growth Biology Laboratory, USDA-ARS, Beltsville, MD, USA

    Timothy G. Ramsay

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  1. C. Richard Barb
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  2. Gary J. Hausman
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  3. Timothy G. Ramsay
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Editors and Affiliations

  1. Texas Tech University School of Medicine, Lubbock, Texas, USA

    V. Daniel Castracane PhD (Professor Emeritus and Director of Laboratory Operations) (Professor Emeritus and Director of Laboratory Operations)

  2. Foundation for Blood Research, P. O. Box 190, Scarborough, ME, USA

    V. Daniel Castracane PhD (Professor Emeritus and Director of Laboratory Operations) (Professor Emeritus and Director of Laboratory Operations)

  3. Department of Biological Sciences, Purdue University Calumet, Hammond, Indiana, USA

    Michael C. Henson PhD (Professor and Head) (Professor and Head)

  4. Dept. of Obstetrics and Gynecology, School of Medicine, Tulane University Health Sciences, New Orleans, LA, USA

    Michael C. Henson PhD (Professor and Head) (Professor and Head)

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Barb, C.R., Hausman, G.J., Ramsay, T.G. (2006). Leptin in Farm Animals. In: Castracane, V.D., Henson, M.C. (eds) Leptin. Endocrine Updates, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-31416-7_14

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