Patient-Specific Modeling in Tomorrow's Medicine

Volume 09 of the series Studies in Mechanobiology, Tissue Engineering and Biomaterials pp 103-131


Patient-Specific Modeling of Scoliosis

  • J. Paige LittleAffiliated withPaediatric Spine Research Group, Queensland University of Technology
  • , Clayton J. AdamAffiliated withPaediatric Spine Research Group, Queensland University of Technology Email author 

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Current complication rates for adolescent spinal deformity surgery are unacceptably high and in order to improve patient outcomes, the development of a simulation tool which enables the surgical strategy for an individual patient to be optimized is necessary. In this chapter we will present our work to date in developing and validating patient-specific modeling techniques to simulate and predict patient outcomes for surgery to correct adolescent scoliosis deformity. While these simulation tools are currently being developed to simulate adolescent idiopathic scoliosis patients, they will have broader application in simulating spinal disorders and optimizing surgical planning for other types of spine surgery. Our studies to date have highlighted the need for not only patient-specific anatomical data, but also patient-specific tissue parameters and biomechanical loading data, in order to accurately predict the physiological behaviour of the spine. Even so, patient-specific computational models are the state-of-the-art in computational biomechanics and offer much potential as a pre-operative surgical planning tool.