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Bioinformatic Approaches for Identification of A-to-I Editing Sites

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Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 353))

Abstract

The first discoveries of mammalian A-to-I RNA editing have been serendipitous. In conjunction with the fast advancement in sequencing technology, systematic methods for prediction and detection of editing sites have been developed, leading to the discovery of thousands of A-to-I editing sites. Here we review the state-of-the-art of these methods and discuss future directions.

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  1. Raymond and Beverly Sackler School of Physics and Astronomy, Tel-Aviv University, 69978, Tel Aviv, Israel

    Eli Eisenberg

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Correspondence to Eli Eisenberg .

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  1. , Dept. of Molecular, Cellular and Develop, University of California, Santa Barbara, Santa Barbara, 93106, California, USA

    Charles E. Samuel

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© 2011 Springer-Verlag Berlin Heidelberg

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Eisenberg, E. (2011). Bioinformatic Approaches for Identification of A-to-I Editing Sites. In: Samuel, C. (eds) Adenosine Deaminases Acting on RNA (ADARs) and A-to-I Editing. Current Topics in Microbiology and Immunology, vol 353. Springer, Berlin, Heidelberg. https://doi.org/10.1007/82_2011_147

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