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Functional Neuroimaging Studies in Normal Aging

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Book cover Behavioral Neurobiology of Aging

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 10))

Abstract

With an expanding aging population, it is increasingly important to gain a better understanding of the changes in cognition and neural integrity that occur in normal aging. The advent of non-invasive functional neuroimaging techniques has spurred researchers to examine cognition and neural functioning in healthy older adults. A significant amount of research has been produced since this time and has led to influential theories of aging such as the hemispheric asymmetry reduction for older adults (HAROLD) model and the compensatory recruitment hypothesis. This chapter discusses advances in our understanding of normal aging achieved through the use of functional neuroimaging. Research examining age-related changes in domains such as attention, memory, and executive functioning, as well as imaging of the resting-state and the influences of genetic risk factors (e.g., APOE genotype), are discussed. In conclusion, limitations of the current literature and important avenues for future research are proposed.

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Authors and Affiliations

  1. Department of Psychiarty and Behavioral Sciences, NorthShore University HealthSystem, Evanston, IL, USA

    Leslie M. Guidotti Breting

  2. Department of Psychology, Loyola University Chicago, Chicago, IL, USA

    Elizabeth R. Tuminello

  3. Department of Behavioral Sciences, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL, 60612-3244, USA

    S. Duke Han

Authors
  1. Leslie M. Guidotti Breting
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  2. Elizabeth R. Tuminello
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  3. S. Duke Han
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Corresponding author

Correspondence to S. Duke Han .

Editor information

Editors and Affiliations

  1. School of Biomedical Sciences, Inst. Neuroscience, University of Nottingham, Nottingham, NG7 2UH, United Kingdom

    Marie-Christine Pardon

  2. Div. Geriatric Psychiatry, University of California, San Diego, Gilman Drive 9500, La Jolla, 92093-0603, California, USA

    Mark W. Bondi

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© 2011 Springer-Verlag Berlin Heidelberg

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Guidotti Breting, L.M., Tuminello, E.R., Duke Han, S. (2011). Functional Neuroimaging Studies in Normal Aging. In: Pardon, MC., Bondi, M. (eds) Behavioral Neurobiology of Aging. Current Topics in Behavioral Neurosciences, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2011_139

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