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Emerging Organic Contaminants in Sludges pp 165–213Cite as

Biodegradation of Pharmaceuticals by Fungi and Metabolites Identification

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Part of the book series: The Handbook of Environmental Chemistry ((HEC,volume 24))

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Abbreviations

ABTS:

2,2-Azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) diammonium salt

BSTR:

Batch stirred tank reactor

CLEAs:

Cross-linked enzyme aggregates

DMHAP:

3,5-Dimethoxy-4-hydroxyacetophenol

E1:

Estrone

E2:

17β-Estradiol

E3:

Estriol

EC50 :

Half maximal effective concentration

EE2:

17α-Ethinyl estradiol

FBR:

Fluidized bed reactor

HBT:

1-Hydroxybenzotriazole

HPLC:

High performance liquid chromatography

HRT:

Hydraulic retention time

LAC:

Laccase

LiP:

Lignin peroxidase

LME:

Lignin modifying enzymes

MnP:

Manganese peroxidase

PBR:

Packed-bed reactor

SYD:

Syringaldehyde

TP:

Transformation products

VA:

Violuric acid

VP:

Versatile peroxidase

WRF:

White-rot fungi

WWTP:

Wastewater treatment plant

References

  1. Rodríguez-Rodríguez CE, Caminal G, Vicent T, Díaz-Cruz MS, Eljarrat E, López de Alda M, Petrovic M, Barceló D (2012) In: Vicent T et al (eds) Emerging organic contaminants in sludges: analysis, fate and biological treatment, Hdb Env Chem, doi:10.1007/698_2012_159, Springer-Verlag, Berlin Heidelberg

  2. Hernandez-Raquet G (2012) In: Vicent T et al (eds) Emerging organic contaminants in sludges: analysis, fate and biological treatment, Hdb Env Chem, doi: 10.1007/698_2012_160, Springer-Verlag, Berlin Heidelberg

  3. Marco-Urrea E, Pérez-Trujillo M, Vicent T, Caminal G (2009) Chemosphere 74:765

    Article  CAS  Google Scholar 

  4. Rodarte-Morales AI, Feijoo G, Moreira MT, Lema JM (2011) World J Microbiol Biotechnol 27:1839

    Article  Google Scholar 

  5. Tran NH, Urase T, Kusakabe O (2010) J Water Environ Technol 8:125

    Article  Google Scholar 

  6. Rodarte-Morales AI, Feijoo G, Moreira MT, Lema JM (2011) Biodegradation 22:539

    Article  Google Scholar 

  7. Marco-Urrea E, Perez-Trujillo M, Cruz-Morató C, Caminal G, Vicent T (2010) J Hazard Mater 176:836

    Article  CAS  Google Scholar 

  8. Lloret L, Eibes G, Lú-Chau TA, Moreira MT, Feijoo G, Lema JM (2010) Biochem Eng J 51:124

    Article  CAS  Google Scholar 

  9. Eibes G, Debernardi G, Feijoo G, Moreira MT, Lema JM (2011) Biodegradation 22:539

    Article  CAS  Google Scholar 

  10. Zhang Y, Geiβen SU (2010) J Hazard Mater 176:1089

    Article  CAS  Google Scholar 

  11. Hata T, Shintate H, Kawai S, Okamura H, Nishida T (2010) J Hazard Mater 181:1175

    Article  CAS  Google Scholar 

  12. Marco-Urrea E, Perez-Trujillo M, Blánquez P, Vicent T, Caminal G (2010) Bioresour Technol 101:2159

    Article  CAS  Google Scholar 

  13. Marco-Urrea E, Perez-Trujillo M, Cruz-Morató C, Caminal G, Vicent T (2010) Chemosphere 78:474

    Article  CAS  Google Scholar 

  14. Golan-Rozen N, Chefetz B, Ben-Ari J, Geva J, Hadar Y (2011) Environ Sci Technol 45:6800

    Article  CAS  Google Scholar 

  15. Jelic A, Cruz-Morato C, Perez S, Marco-Urrea E, Sarrà M, Vicent T, Petrovic M, Barcelo D (2011) Water Res 46:955

    Article  Google Scholar 

  16. Kang S, Kang SY, Hur H (2008) Appl Microbiol Biotechnol 79:663

    Article  CAS  Google Scholar 

  17. Marco-Urrea E, Radjenovic J, Caminal G, Petrovic M, Vicent T, Barcelo D (2010) Water Res 44:521

    Article  CAS  Google Scholar 

  18. Sillanpaa M (1996) In: Wyllie E (ed) The treatment of epilepsy, vol 2. Philadelphia, p 808

    Google Scholar 

  19. Lertratanangkoon K, Horning MG (1982) Drug Metab Dispos 10:1

    CAS  Google Scholar 

  20. Petrovic M, de Alda M, Diaz-Cruz S, Postigo C, Radjenovic J, Gros M, Barcelo D (2009) Math Phys Eng Sci 367:3979

    Article  CAS  Google Scholar 

  21. Jia A, Hu JY, Sun JX, Shi JC (2009) Prog Chem 21:389

    CAS  Google Scholar 

  22. Schwarz J, Aust MO, Thiele-Bruhn S (2010) Chemosphere 81:1469

    Article  CAS  Google Scholar 

  23. García-Galán MJ, Rodríguez-Rodríguez CE, Vicent T, Caminal G, Díaz-Cruz MS, Barceló D (2011) Sci Total Environ 409:5505

    Article  Google Scholar 

  24. Rodríguez-Rodríguez CE, García-Galán MJ, Blánquez P, Díaz-Cruz MS, Barceló D, Caminal G, Vicent T (2012) J Hazard Mater 213–214:347

    Article  Google Scholar 

  25. Accinelli C, Saccà ML, Batisson I, Fick J, Mencarelli M, Grabic R (2010) Chemosphere 81:436

    Article  CAS  Google Scholar 

  26. Wen X, Jis Y, Li J (2009) Chemosphere 75:1003

    Article  CAS  Google Scholar 

  27. Suda T, Hata T, Kawai S, Okamura H, Nishida T (2012) Bioresour Technol 103:4998

    Article  Google Scholar 

  28. Wetzstein HG, Stadler M, Tichy HV, Dalhoff A, Karl W (1999) Appl Environ Microbiol 65:1556

    CAS  Google Scholar 

  29. Prieto A, Möder M, Rodil R, Lorenz A, Marco-Urrea M (2011) Bioresour Technol 102:10987

    Article  CAS  Google Scholar 

  30. Parshikov IA, Heinze TM, Moody JD, Freeman JP, Williams AJ, Sutherland JB (2001) Appl Microbiol Biotechnol 56:474

    Article  CAS  Google Scholar 

  31. Parshikov IA, Freeman JP, Lay JO, Beger RD, Williams AJ, Sutherland JB (1999) Microbiol Lett 177:131

    Article  CAS  Google Scholar 

  32. Parshikov IA, Moody JD, Freeman JP, Lay JO, Williams AJ, Heinze TM, Sutherland JB (2002) Mycologia 94:1

    Article  CAS  Google Scholar 

  33. Martens R, Wetzstein HG, Zadrazil F, Capelari M, Hoffmann P, Schmeer N (1996) Appl Environ Microbiol 62:4206

    CAS  Google Scholar 

  34. Wetzstein HG, Schmeer N, Karl W (1997) Appl Microbiol Biotechnol 63:4272

    CAS  Google Scholar 

  35. Wetzstein HG, Schneider J, Karl W (2006) Appl Microbiol Biotechnol 71:90

    Article  CAS  Google Scholar 

  36. Parshikov IA, Freeman JP, Lay JO, Beger RD, Williams AJ, Sutherland JB (2000) Appl Environ Microbiol 66:2664

    Article  CAS  Google Scholar 

  37. Parshikov IA, Freeman JP, Lay JO, Moody JD, Williams AJ, Beger RD, Sutherland JB (2001) J Ind Microbiol Biotechnol 26:140

    Article  CAS  Google Scholar 

  38. Williams AJ, Deck J, Freeman JP, Chiarelli MP, Adjei MD, Heinze TM, Sutherland JB (2007) Chemosphere 67:240

    Article  CAS  Google Scholar 

  39. Parshikov IA, Moody JD, Heinze TM, Freeman JP, Williams AJ, Sutherland JB (2002) FEMS Microbiol Lett 214:133

    Article  CAS  Google Scholar 

  40. Kim YJ, Nicell JA (2006) J Chem Technol Biotechnol 81:1344

    Article  CAS  Google Scholar 

  41. Inoue Y, Hata T, Kawai S, Okamura H, Nishida T (2010) J Hazard Mater 180:764

    Article  CAS  Google Scholar 

  42. Cabana H, Jones JP, Agathos SN (2007) J Biotechnol 132:23

    Article  CAS  Google Scholar 

  43. Cabana H, Alexandre C, Agathos SN, Jones JP (2009) Bioresour Technol 100:3447

    Article  CAS  Google Scholar 

  44. Taboada-Puig R, Junghanns C, Demarche P, Moreira MT, Feijoo G, Lema JM, Agathos SN (2011) Bioresour Technol 102:6593

    Article  CAS  Google Scholar 

  45. Cabana H, Jones JP, Agathos SN (2009) Biotechnol Bioeng 102:1582

    Article  CAS  Google Scholar 

  46. Cabana H, Ahamed A, Leduc R (2011) Bioresour Technol 102:1656

    Article  CAS  Google Scholar 

  47. Murugesan K, Chang YY, Kim YM, Jeon JR, Kim EJ, Chang YS (2010) Water Res 44:298

    Article  CAS  Google Scholar 

  48. Cabana H, Jiwan JLH, Rozenberg R, Elisashvili V, Penninckx M, Agathos SN, Jones JP (2007) Chemosphere 67:770

    Article  CAS  Google Scholar 

  49. Hundt K, Martin D, Hammer E, Jonas U, Kindermann MK, Schauer F (2000) Appl Environ Microbiol 66:4157

    Article  CAS  Google Scholar 

  50. Cajthalm T, Křesinová S, Svobodová K, Möder M (2009) Chemosphere 75:745

    Article  Google Scholar 

  51. Parshikov IA, Freeman JP, Williams AJ, Moody JD, Sutherland JB (1999) Appl Microbiol Biotechnol 52:553

    Article  CAS  Google Scholar 

  52. Parshikov IA, Miriyala B, Muraleedharan KM, Avery MA, Williamson JS (2006) J Ind Microbiol Biotechnol 33:349

    Article  CAS  Google Scholar 

  53. Parshikov IA, Miriyala B, Muraleedharan KM, Illendula A, Avery MA, Williamson JS (2005) Pharm Biol 43:579

    Article  CAS  Google Scholar 

  54. Parshikov IA, Muraleedharan KM, Avery MA, Williamson JS (2004) Appl Microbiol Biotechnol 64:782

    Article  CAS  Google Scholar 

  55. Suzuki K, Hirai H, Murata H, Nishida T (2003) Water Res 37:1972

    Article  CAS  Google Scholar 

  56. Tamagawa Y, Yamaki R, Hirai H, Kawai S, Nishida T (2006) Chemosphere 65:97

    Article  CAS  Google Scholar 

  57. Nicotra S, Intra A, Ottolina G, Riva S, Danieli B (2004) Asymmetry 15:2927

    Article  CAS  Google Scholar 

  58. Lloret L, Eibes G, Feijoo G, Moreira MT, Lema JM (2011) Biotechnol Prog 27:668

    Article  Google Scholar 

  59. Auriol M, Filali-Meknassi Y, Tyagi RD, Adams CD (2007) Water Res 41:3281

    Article  CAS  Google Scholar 

  60. Auriol M, Filali-Meknassi Y, Adams CD, Tyagi RD, Noguerol TN, Piña B (2008) Chemosphere 70:445

    Article  CAS  Google Scholar 

  61. Blánquez P, Guieysse B (2008) J Hazard Mater 150:459

    Article  Google Scholar 

  62. Rode U, Müller R (1998) Appl Environ Microbiol 64:3114

    CAS  Google Scholar 

  63. Rode U, Müller R (1999) Biol Abwass 12:63

    CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the Spanish Ministries of MMAMRM (project 010/PC08/3-04) and MICINN (project CTQ2010-21776-C02-01). The Department of Chemical Engineering of the Universitat Autònoma de Barcelona (UAB) is the Unit of Biochemical Engineering of the Xarxa de Referència en Biotecnologia de la Generalitat de Catalunya. The authors are members of a Consolidated Research Group of Catalonia (2009-SGR-656). C. Cruz-Morató acknowledges the predoctoral grant from UAB. C.E. Rodríguez-Rodríguez is recipient of a predoctoral fellowship from Universidad de Costa Rica and Consejo Superior de Investigaciones Científicas (UCR-CSIC collaboration).

Author information

Authors and Affiliations

  1. Departament d’Enginyeria Química, Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Spain

    C. Cruz-Morató, E. Marco-Urrea, M. Sarrà & T. Vicent

  2. Unitat Asociada de Biocatàlisi Aplicada IQAC-CSIC, Escola d’Enginyeria, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain

    C. E. Rodríguez-Rodríguez

  3. Centro de Investigación en Contaminación Ambiental (CICA), Universidad de Costa Rica, 2060, San José, Costa Rica

    C. E. Rodríguez-Rodríguez

  4. Grupo de biocatalisis Aplicada y biodegradación, IQAC-CSIC, C/Jordi Girona 18-26, 08034, Barcelona, Spain

    G. Caminal

  5. Department of Environmental Chemistry, IDAEA, CSIC, Jordi Girona 18-26, 08034, Barcelona, Spain

    A. Jelić, M. J. García-Galán, S. Pérez, M. S. Díaz-Cruz & D. Barceló

  6. ICREA Institució Catalana de Recerca i Estudis Avançats, Passeig Lluís Companys, 2308010, Barcelona, Spain

    M. Petrović

  7. Catalan Institute for Water Research (ICRA), Parc Científic i Tecnològic de la Universitat de Girona, C/ Emili Grahit, 101 Edifici H2O, 17003, Girona, Spain

    M. Petrović & D. Barceló

Authors
  1. C. Cruz-Morató
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  2. C. E. Rodríguez-Rodríguez
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  3. E. Marco-Urrea
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  5. G. Caminal
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  6. T. Vicent
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  7. A. Jelić
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  8. M. J. García-Galán
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  9. S. Pérez
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  10. M. S. Díaz-Cruz
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  11. M. Petrović
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  12. D. Barceló
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Corresponding author

Correspondence to M. Petrović .

Editor information

Editors and Affiliations

  1. , Chemical Engineering Department, Universitat Autònoma de Barcelona, N/A, Bellaterra, 08193, Barcelona, Spain

    Teresa Vicent

  2. , Grupo de biocatalisis Aplicada y biodegr, IQAC-CSIC, C/Jordi Girona 18-26, Barcelona, 08034, Spain

    Glòria Caminal

  3. Department of Environmental Chemistry, IDAEA-CSIC, c/Jordi Girona 18-26, Barcelona, 08034, Spain

    Ethel Eljarrat

  4. , Department of Environmental Chemistry, IDAEA-CSIC, c/Jordi Girona 18-26, Barcelona, 08034, Spain

    Damià Barceló

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© 2012 Springer-Verlag Berlin Heidelberg

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Cruz-Morató, C. et al. (2012). Biodegradation of Pharmaceuticals by Fungi and Metabolites Identification. In: Vicent, T., Caminal, G., Eljarrat, E., Barceló, D. (eds) Emerging Organic Contaminants in Sludges. The Handbook of Environmental Chemistry, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/698_2012_158

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