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Malnutrition and Quality of Life in Patients with Non-Small-Cell Lung Cancer

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Pulmonary Care and Clinical Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 1021))

Abstract

Progressive weight loss, common reduces performance and quality of life in patients with advanced lung cancer. However, there is a paucity of studies that focus on nutritional status and quality of life of non-small cell lung cancer (NSCLC) patients. The present study seeks to determine the nutritional status, and its relation to quality of life, of NSCLC patients. One hundred and eighty NSCLC patients (mean age 62.8 ± 9.6 years) were evaluated during therapy at the Lower Silesian Center of Lung Diseases in Wroclaw, Poland. Nutritional status was evaluated by means of the Mini-Nutritional Assessment (MNA) and quality of life by means of two instruments developed by the European Organization for the Research and Treatment of Cancer (EORTC): QLQ-C30 and QLQ-LC13 questionnaires. The MNA revealed that up to 51.1% of patients were undernourished, 23.9% were at risk of malnutrition, and only 25.0% showed a normal nutrition. The well-nourished respondents evaluated their quality of life better in all functional scales (33.3 vs. 41.7 vs. 66.7, respectively) and presented less intensive symptoms in general QLQ-C30 and specific LC13 questionnaires. In univariate analysis, malnutrition significantly correlated with decreased quality of life and the intensity of symptoms in both questionnaires. In multivariate analysis, malnutrition was an independent determinant of decreased quality of life in physical functioning domain (β = −0.015; p < 0.001). We conclude that malnutrition has an impact on quality of life and on the presentation of symptoms in NSCLC patients. Therefore, nutritional care should be integrated into the global oncology as an adjunct to symptomatic treatment.

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Conflicts of Interest

The author declare no conflicts of interest in relation to this article.

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Authors and Affiliations

  1. Lower Silesian Oncology Center, Home Hospice, 12 Hirszfeld Square, Wroclaw, 53-413, Poland

    Jacek Polański

  2. Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 5 Bartla Streetd, Wroclaw, 51-618, Poland

    Beata Jankowska-Polańska & Izabella Uchmanowicz

  3. Division of Surgical Procedures, Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 5 Bartla Street, Wroclaw, 51-618, Poland

    Mariusz Chabowski & Dariusz Janczak

  4. Department of Surgery, Fourth Military Teaching Hospital, 5 Weigla Street, Wroclaw, 50-981, Poland

    Mariusz Chabowski

  5. Department of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 213 Borowska Street, Wroclaw, 50-556, Poland

    Grzegorz Mazur

  6. Department of Nervous System Diseases, Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, 5 Bartla Street, Wroclaw, 51-618, Poland

    Joanna Rosińczuk

Authors
  1. Jacek Polański
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  2. Beata Jankowska-Polańska
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  3. Izabella Uchmanowicz
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Correspondence to Mariusz Chabowski .

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  1. Opole Medical School, Opole, Poland

    Mieczyslaw Pokorski

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Polański, J. et al. (2017). Malnutrition and Quality of Life in Patients with Non-Small-Cell Lung Cancer. In: Pokorski, M. (eds) Pulmonary Care and Clinical Medicine. Advances in Experimental Medicine and Biology(), vol 1021. Springer, Cham. https://doi.org/10.1007/5584_2017_23

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