Advances in Biochemical Engineering, Volume 15

Volume 15 of the series Advances in Biochemical Engineering pp 1-40


The loop reactor for cultivating yeast on n-paraffin substrate

  • Reinhold SeipenbuschAffiliated withVEBA-Chemie AG, Werksgruppe Herne
  • , Heinz BlenkeAffiliated withInstitut für Chemische Verfahrenstechnik, Universität Stuttgart

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For economic mass production by a microbial process, e.g., of single cell protein from a petroleum fraction it is important to find a type of reactor that meets the following requirements:
  • -large mass-transfer rate for oxygen and substrate at low energy input;

  • -the reactor must be capable of being constructed and operated in large units;

  • -a simple and robust design, which is characterized by low construction costs, easy to keep sterile, low maintenance costs, and a high on-stream availability.

The loop reactor, especially the jet loop reactor, is examined with regard to its suitability as a bioreactor; in this context the O2 transfer, the substrate transfer, the necessary energy input and the flow pattern are dealt with. The optimal operating conditions (minimum energy input) regarding O2 conversion and jet power input under consideration of a favorable flow pattern are presented. It is shown that the controllability of the reactor meets the requirements of the culture.

As an example of economically optimal SCP production, the cultivation of yeast on n-paraffin substrate is analysed.