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Copper-Mediated Intermolecular C–H/C–H and C–H/N–H Couplings via Aromatic C–H Cleavage

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C-H Bond Activation and Catalytic Functionalization II

Part of the book series: Topics in Organometallic Chemistry ((volume 56))

Abstract

Copper salts and complexes have recently received significant attention as less expensive and abundant alternatives to some noble transition metal catalysts such as palladium, rhodium, and ruthenium, in the research field of C–H activation. They not only replace the above precious metal catalysts in the known C–H transformations but also mediate unique, otherwise challenging, cross-coupling reactions involving C–H bond cleavage. This chapter mainly focuses on recent advances in the copper-mediated or copper-catalyzed intermolecular C–H/C–H and C–H/N–H aromatic couplings. Seminal mechanistic studies on the copper-mediated C–H functionalization are also discussed.

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Author information

Authors and Affiliations

  1. Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka, 565-0871, Japan

    Koji Hirano & Masahiro Miura

Authors
  1. Koji Hirano
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  2. Masahiro Miura
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Corresponding authors

Correspondence to Koji Hirano or Masahiro Miura .

Editor information

Editors and Affiliations

  1. Université de Rennes, Rennes, France

    Pierre H. Dixneuf

  2. Université de Rennes, Rennes, France

    Henri Doucet

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Hirano, K., Miura, M. (2015). Copper-Mediated Intermolecular C–H/C–H and C–H/N–H Couplings via Aromatic C–H Cleavage. In: Dixneuf, P., Doucet, H. (eds) C-H Bond Activation and Catalytic Functionalization II. Topics in Organometallic Chemistry, vol 56. Springer, Cham. https://doi.org/10.1007/3418_2015_116

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