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Perioperative Hämostasestörungen und Transfusion in der Kardiochirurgie

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Empfehlungen zum Einsatz und zur Verwendung der Herz-Lungen-Maschine

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3.6 Literatur

  1. Agarwal SK, Ghosh PK, Gupta D (1995) Cardiac surgery and cold-reactive proteins. Ann Thorac Surg 60:1143–1150

    Article  PubMed  CAS  Google Scholar 

  2. Aggarwal A, Malkovska V, Catlett JP et al. (2004) Recombinant activated factor VII (rFVIIa) as salvage treatment for intractable hemorrhage. Thromb J 2:9

    Article  PubMed  Google Scholar 

  3. Aldea GS, Soltow LO, Chandler WL et al. (2002) Limitation of thrombin generation, platelet activation, and inflammation by elimination of cardiotomy suction in patients undergoing coronary artery bypass grafting treated with heparin-bonded circuits. J Thorac Cardiovasc Surg 123:742–755

    Article  PubMed  Google Scholar 

  4. Baltalari A, Keskin A, Sirin BH (2000) Warm heart surgery for the patient with cold agglutinins. The Internet Journal of Thoracic and Cardiovascular Surgery, Vol. 3, No 2

    Google Scholar 

  5. Beierlein W, Scheule M, Dietrich W et al. (2005) Forty years of clinical aprotinin use: a review of 124 hypersensitivity reactions. Ann Thorac Surg 79:741–748

    Article  PubMed  Google Scholar 

  6. Boldt J, Knothe C, Welters I et al. (1996) Normothermic versus hypo thermic cardiopulmonary bypass: do changes in coagulation differ? Ann Thorac Surg 62:130–135

    Article  PubMed  CAS  Google Scholar 

  7. Carr JA, Silverman N (1999) The heparin-protamine interaction. A review. J Cardiovasc Surg (Torino) 40:659–666

    CAS  Google Scholar 

  8. Cattaneo M, Harris AS, Stromberg U et al. (1995) The effect of desmopressin on reducing blood loss in cardiac surgery — a meta-analysis of double-blind, placebo-controlled trials. Thromb Haemost 74:1064–1070

    PubMed  CAS  Google Scholar 

  9. Chung JH, Gikakis N, Rao AK et al. (1996) Pericardial blood activates the extrinsic coagulation pathway during clinical cardiopulmonary bypass. Circulation 93:2014–2018

    PubMed  CAS  Google Scholar 

  10. de Haan J, Boonstra PW, Monnink SH et al. (1995) Retransfusion of suctioned blood during cardiopulmonary bypass impairs hemostasis. Ann Thorac Surg 59:901–907

    Article  PubMed  Google Scholar 

  11. Despotis GJ, Filos KS, Zoys TN et al. (1996) Factors associated with excessive postoperative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients. Anesth Analg 82:13–21

    Article  PubMed  CAS  Google Scholar 

  12. Diaz JH, Cooper ES, Ochsner Jl (1984) Cardiac surgery in patients with cold autoimmune diseases. Anesth Analg 63:349–352

    Article  PubMed  CAS  Google Scholar 

  13. Dietrich W, Thuermel K, Heyde S, Busley R, Berger K (2005) Autologous blood donation in cardiac surgery: reduction of allogeneic blood transfusion and cost-effectiveness. J Cardiothorac Vasc Anesth 19:589–596

    Article  PubMed  Google Scholar 

  14. Dilthey G, Dietrich W, Spannagl M et al. (1993) Influence of desmopressin acetate on homologous blood requirements in cardiac surgical patients pretreated with aspirin. J Cardiothorac Vasc Anesth 7:425–430

    Article  PubMed  CAS  Google Scholar 

  15. Franke UF, Korsch S, Wittwer T, Albes JM, Wippermann J, Kaluza M et al. (2003) Intermittent antegrade warm myocardial protection compared to intermittent cold blood cardioplegia in elective coronary surgery — do we have to change? Eur J Cardiothoracic Surg 23(3):341–346

    Article  Google Scholar 

  16. Herbertson M (2004) Recombinant activated factor VII in cardiac surgery. Blood Coagul Fibrinolysis 15(Suppl 1):S31–S32

    Article  PubMed  CAS  Google Scholar 

  17. Holloway DS, Summaria L, Sandesara J et al. (1988) Decreased platelet number and function and increased fibrinolysis contribute to postoperative bleeding in cardiopulmonary bypass patients. Thromb Haemost 59:62–67

    PubMed  CAS  Google Scholar 

  18. Laupacis A, Fergusson D (1997) Drugs to minimize perioperative blood loss in cardiac surgery: meta-analyses using perioperative blood transfusion as the outcome. The International Study of Perioperative Transfusion (ISPOT) Investigators. Anesth Analg 85:1258–1267

    Article  PubMed  CAS  Google Scholar 

  19. Leitlinien zur Therapie mit Blutkomponenten und Plasmaderivaten (2003) Vorstand und Wissenschaftlicher Beirat der Bundesärztekammer. Deutscher Ärzte-Verlag, Köln

    Google Scholar 

  20. Levy JH, Tanaka KA (2003) Inflammatory response to cardiopulmonary bypass. Ann Thorac Surg 75:S715–S720

    Article  PubMed  Google Scholar 

  21. Levy JH, Tanaka KA, Steiner ME (2005) Evaluation and management of bleeding during cardiac surgery. Curr Hematol Rep 4(5):368–372

    PubMed  Google Scholar 

  22. Litmathe J, Boeken U, Feindt P, Gams E (2003) Predictors of homologous blood transfusion for patients undergoing open heart surgery. Thorac Cardiovasc Surg 51:17–21

    Article  PubMed  CAS  Google Scholar 

  23. Mahdy AM, Webster NR (2004) Perioperative systemic haemostatic agents. Br J Anaesth 93:842–858

    Article  PubMed  CAS  Google Scholar 

  24. McDOnald MB, McMillan J (2005) Predicting blood usage in cardiac surgery-the transfusion predictor product. J Extra Corpor Technol 37(2):157–160

    PubMed  Google Scholar 

  25. Michelson AD, MacGregor H, Barnard MR et al. (1994) Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro. Thromb Haemost 71:633–640

    PubMed  CAS  Google Scholar 

  26. Mochizuki T, Olson PJ, Szlam F et al. (1998) Protamine reversal of heparin affects platelet aggregation and activated clotting time after cardiopulmonary bypass. Anesth Analg 87:781–785

    Article  PubMed  CAS  Google Scholar 

  27. Munoz JJ, Birkmeyer NJ, Birkmeyer JD et al. (1999) Is epsilon-aminocaproic acid as effective as aprotinin in reducing bleeding with cardiac surgery?: a meta-analysis. Circulation 99:81–89

    PubMed  CAS  Google Scholar 

  28. Murphy GJ, Ascione R, Angelini GD (2004) Coronary artery bypass grafting on the beating heart: surgical revascularization for the next decade? Eur Heart J 25:2077–2085

    Article  PubMed  Google Scholar 

  29. Norfolk DR, Ancliffe PJ, Contreras M et al. (1998) Consensus Conference on Platelet Transfusion, Royal College of Physicians of Edinburgh, 27–28 November 1997. Synopsis of background papers. Br J Haematol 101:609–617

    Article  PubMed  CAS  Google Scholar 

  30. Parr KG, Patel MA, Dekker R et al. (2003) Multivariate predictors of blood product use in cardiac surgery. J Cardiothorac Vasc Anesth 17:176–181

    Article  PubMed  Google Scholar 

  31. Peyrou V, Lormeau JC, Herault JP et al. (1999) Contribution of erythrocytes to thrombin generation in whole blood. Thromb Haemost 81:400–406

    PubMed  CAS  Google Scholar 

  32. Schmidt PJ (1985) Cold agglutinins and hypothermia. Arch Intern Med 145:578–579

    Article  PubMed  CAS  Google Scholar 

  33. Sellman M, Intonti MA, Ivert T (1997) Reoperations for bleeding after coronary artery bypass procedures during 25 years. Eur J Cardiothorac Surg 11:521–527

    Article  PubMed  CAS  Google Scholar 

  34. Stanworth SJ, Brunskill SJ, Hyde CJ et al. (2004) Is fresh frozen plasma clinically effective? A systematic review of randomized controlled trials. Br J Haematol 126:139–152

    Article  PubMed  CAS  Google Scholar 

  35. Teufelsbauer H, Proidl S, Havel M et al. (1992) Early activation of hemostasis during cardiopulmonary bypass: evidence for thrombin mediated hyperfibrinolysis. Thromb Haemost 68:250–252

    PubMed  CAS  Google Scholar 

  36. Uijttewaal WS, Nijhof EJ, Bronkhorst PJ et al. (1993) Near-wall excess of platelets induced by lateral migration of erythrocytes in flowing blood. Am J Physiol 264:H1239–H1244

    PubMed  CAS  Google Scholar 

  37. Unsworth-White MJ, Herriot A, Valencia O et al. (1987) Resternotomy for bleeding after cardiac operation: a marker for increased morbidity and mortality. Ann Thorac Surg 59:664–667

    Google Scholar 

  38. Valeri CR, Feingold H, Cassidy G et al. (1987) Hypothermia-induced reversible platelet dysfunction. Ann Surg 205:175–181

    PubMed  CAS  Google Scholar 

  39. Valles J, Santos MT, Aznar J et al. (1991) Erythrocytes metabolically enhance collagen-induced platelet responsiveness via increased thromboxane production, adenosine diphosphate release, and recruitment. Blood 78:154–162

    PubMed  CAS  Google Scholar 

  40. von Heymann C, Schoenfeld H, Sander M et al. (2005) Clopidogrel-related refractory bleeding after coronary artery bypass graft surgery: a rationale for the use of coagulation factor concentrates? Heart Surg Forum 8:E39–41

    Google Scholar 

  41. Weerasinghe A, Taylor KM (1998) The platelet in cardiopulmonary bypass. Ann Thorac Surg 66:2145–2152

    Article  PubMed  CAS  Google Scholar 

  42. Wells PS (2002) Safety and efficacy of methods for reducing perioperative allogeneic transfusion: a critical review of the literature. Am J Ther 9:377–388

    Article  PubMed  Google Scholar 

  43. Ziats NP, Pankowsky DA, Tierney BP et al. (1990) Adsorption of Hageman factor (factor XII) and other human plasma proteins to biomedical polymers. J Lab Clin Med 116:687–696

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Institut für Hämostaseologie und Transfusionsmedizin, Heinrich-Heine-Universität Düsseldorf, Moorenstr. 5, 40225, Düsseldorf

    Dr. med. C. Sucker

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  1. Dr. med. C. Sucker
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Editors and Affiliations

  1. Klinik für Thorax- und Kardiovaskuläre Chirurgie, Universitäts-Klinikum Düsseldorf, Heinrich-Heine-Universität, Moorenstrasse 5, 40225, Düsseldorf

    Peter Feindt

  2. Zentrum für Herzchirurgie Erlangen-Nürnberg, Universitätsklinikum Erlangen, Krankenhausstr. 12, 91054, Erlangen

    Frank Harig  & Michael Weyand  & 

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© 2006 Steinkopff Verlag Darmstadt

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Sucker, C. (2006). Perioperative Hämostasestörungen und Transfusion in der Kardiochirurgie. In: Feindt, P., Harig, F., Weyand, M. (eds) Empfehlungen zum Einsatz und zur Verwendung der Herz-Lungen-Maschine. Steinkopff. https://doi.org/10.1007/3-7985-1646-4_4

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  • DOI: https://doi.org/10.1007/3-7985-1646-4_4

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-7985-1504-8

  • Online ISBN: 978-3-7985-1646-5

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