Skip to main content

Glutamate dehydrogenase (NADP+)

  • Chapter
  • 601 Accesses

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume 22))

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bhuiya, M.W.; Sakuraba, H.; Ohshima, T.: Temperature dependence of kinetic parameters for hyperthermophilic glutamate dehydrogenase from Aeropyrum pernix Kl. Biosci. Biotechnol. Biochem., 66, 873–876 (2002)

    Article  PubMed  CAS  Google Scholar 

  2. Robb, F.T.; Maeder, D.L.; DiRuggiero, J.; Borges, K.M.; Tolliday, N.: Glutamate dehydrogenases from hyperthermophiles. Methods Enzymol., 331, 26–41 (2001)

    PubMed  CAS  Google Scholar 

  3. Steen, I.H.; Hvoslef, H.; Lien, T.; Birkeland, N.K.: Isocitrate dehydrogenase, malate dehydrogenase, and glutamate dehydrogenase from Archaeoglobus fulgidus. Methods Enzymol., 331, 13–26 (2001)

    PubMed  CAS  Google Scholar 

  4. DeLuna, A.; Avendano, A.; Riego, L.; Gonzalez, A.: NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles. J. Biol. Chem., 276, 43775–43783 (2001)

    Article  PubMed  CAS  Google Scholar 

  5. Helianti, I.; Morita, Y.; Yamamura, A.; Murakami, Y.; Yokoyama, K.; Tamiya, E.: Characterization of native glutamate dehydrogenase from an aerobic hyperthermophilic archaeon Aeropyrum pernix Kl. Appl. Microbiol. Biotechnol., 56, 388–394 (2001)

    Article  PubMed  CAS  Google Scholar 

  6. Di Fraia, R.; Wilquet, V.; Ciardiello, M.A.; Carratore, V.; Antignani, A.; Camardella, L.; Glansdorff, N.; Di Prisco, G.: NADP+-dependent glutamate dehydrogenase in the antarctic psychrotolerant bacterium Psychrobacter sp. TAD1. Characterization, protein and DNA sequence, and relationship to other glutamate dehydrogenases. Eur. J. Biochem., 267, 121–131 (2000)

    Article  PubMed  Google Scholar 

  7. Bhuiya, M.W.; Sakuraba, H.; Kujo, C.; Nunoura-Kominato, N.; Kawarabayasi, Y.; Kikuchi, H.; Ohshima, T.: Glutamate dehydrogenase from the aerobic hyperthermophilic archaeon Aeropyrum pernix Kl: enzymatic characterization, identification of the encoding gene, and phylogenetic implications. Extremophiles, 4, 333–341 (2000)

    Article  PubMed  CAS  Google Scholar 

  8. Lebbink, J.H.; Knapp, S.; van der Oost, J.; Rice, D.; Ladenstein, R.; de Vos, W.M.: Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. II: construction of a 16-residue ion-pair network at the subunit interface. J. Mol. Biol., 289, 357–369 (1999)

    Article  PubMed  CAS  Google Scholar 

  9. Rahman, R.N.Z.A.; Fujiwara, S.; Nakamura, H.; Takagi, M.; Imanaka, T.: Ion pairs involved in maintaining a thermostable structure of glutamate dehydrogenase from a hyperthermophilic archaeon. Biochem. Biophys. Res. Commun., 248, 920–926 (1998)

    Article  PubMed  CAS  Google Scholar 

  10. Park, J.H.; Schofield, P.J.; Edwards, M.R.: Giardia intestinalis: characterization of a NADP-dependent glutamate dehydrogenase. Exp. Parasitai., 88, 131–138 (1998)

    Article  CAS  Google Scholar 

  11. Aalen, N.; Steen, I.H.; Birkeland, N.K.; Lien, T.: Purification and properties of an extremely thermostable NADP+-specific glutamate dehydrogenase from Archaeoglobus fulgidus. Arch. Microbiol, 168, 536–539 (1997)

    Article  PubMed  CAS  Google Scholar 

  12. Inokuchi, R.; Itagaki, T.; Wiskich, J.T.; Nakayama, K.; Okada, M.: An NADP-glutamate dehydrogenase from the green alga Bryopsis maxima. Purification and properties. Plant Cell Physiol, 38, 327–335 (1997)

    PubMed  CAS  Google Scholar 

  13. Ferrer, J.; Perez-Pomares, F.; Bonete, M.J.: NADP-glutamate dehydrogenase from the halophilic archaeon Haloferax mediterranei: enzyme purification, N-terminal sequence and stability studies. FEMS Microbiol. Lett., 141, 59–63 (1996)

    Article  PubMed  CAS  Google Scholar 

  14. Koike, K.; Hakamada, Y.; Yoshimatsu, T.; Kobayashi, T.; Ito, S.: NADP-specific glutamate dehydrogenase from alkalophilic Bacillus sp. KSM-635: purification and enzymic properties. Biosci. Biotechnol. Biochem., 60, 1764–1767 (1996)

    CAS  Google Scholar 

  15. Bogati, M.S.; Pocsi, I.; Maticsek, J.; Boross, P.; Tozser, J.; Szentirmai, A.: NADP-specific glutamate dehydrogenase of Penicillium chrysogenum has a homohexamer structure. J. Basic Microbiol., 36, 371–375. (1996)

    Article  PubMed  CAS  Google Scholar 

  16. Krauth-Siegel, R.L.; Mueller, J.G.; Lottspeich, F.; Schirmer, R.H.: Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria. Eur. J. Biochem., 235, 345–350 (1996)

    Article  PubMed  CAS  Google Scholar 

  17. Kobayashi, T.; Higuchi, S.; Kimura, K.; Kudo, T.; Horikoshi, K.: Properties of glutamate dehydrogenase and its involvement in alanine production in a hyperthermophilic archaeon, Thermococcus profundus. J. Biochem., 118, 587–592 (1995)

    PubMed  CAS  Google Scholar 

  18. Baars, J.J.P.; Op den Camp, H.J.M.; van Hoek, A.H.A.M.; van der Drift, C.; Van Griensven, L.J.L.D.; Visser, J.; Vogels, G.D.: Purification and characterization of NADP-dependent glutamate dehydrogenase from the commercial mushroom Agaricus bisporus. Curr. Microbiol., 30, 211–217 (1995)

    Article  PubMed  CAS  Google Scholar 

  19. Lebbink, J.H.G.; Eggen, R.I.L.; Geerling, A.C.M.; Consalvi, V.; Chiaraluce, R.; Scandurra, R.; de Vos, W.M.: Exchange of domains of glutamate dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus and the mesophilic bacterium Clostridium difficile: Effects on catalysis, thermoactivity and stability. Protein Eng., 8, 1287–1294 (1995)

    Article  PubMed  CAS  Google Scholar 

  20. Perysinakis, A.; Kinghorn, J.R.; Drainas, C: Biochemical and genetical studies of NADP-specific glutamate dehydrogenase in the fission yeast Schizosaccharomyces pombe. Curr. Genet., 26, 315–320 (1994)

    Article  PubMed  CAS  Google Scholar 

  21. Ma, K.; Robb, F.T.; Adams, M.W.: Purification and characterization of NADP-specific alcohol dehydrogenase and glutamate dehydrogenase from the hyperthermophilic archaeon Thermococcus litoralis. Appl. Environ. Microbiol., 60, 562–568 (1994)

    PubMed  CAS  Google Scholar 

  22. Korber, F.C.; Rizkallah, P.J.; Attwood, T.K.; Wootton, J.C.; McPherson, M.J.; North, A.C.; Geddes, A.J.; Abeysinghe, I.S.; Baker, P.J.; Dean, J.L.; et al.: Crystallization of the NADP(+)-dependent glutamate dehydrogenase from Escherichia coli. J. Mol. Biol., 234, 1270–1273. (1993)

    Article  PubMed  CAS  Google Scholar 

  23. Ohshima, T.; Nishida, N.: Purification and properties of extremely thermostable glutamate dehydrogenase from two hyperthermophilic archaebacteria, Pyrococcus woesei and Pyrococcus furiosus. Biosci. Biotechnol. Biochem., 57, 945–951 (1993)

    Article  PubMed  CAS  Google Scholar 

  24. Hudson, R.C.; Ruttersmith, L.D.; Daniel, R.M.: Glutamate dehydrogenase from the extremely thermophilic archaebacterial isolate AN1. Biochim. Biophys. Acta, 1202, 244–250 (1993)

    PubMed  CAS  Google Scholar 

  25. Lin, H.P.P.; Reeves, H.C.: Purification and characterization of NADP+-specific glutamate dehydrogenase from Escherichia coli. Curr. Microbiol., 22, 371–376 (1991)

    Article  CAS  Google Scholar 

  26. Pamula, F.; Wheldrake, J.E: Purification and properties of the NADP-dependent glutamate dehydrogenase from Dictyostelium discoideum. Mol. Cell. Biochem., 105, 85–92 (1991)

    Article  PubMed  CAS  Google Scholar 

  27. Bonete, M.J.; Camacho, M.L.; Candenas, E.: Analysis of the kinetic mechanism of halophilic NADP-dependent glutamate dehydrogenase. Biochim. Biophys. Acta, 1041, 305–310 (1990)

    PubMed  CAS  Google Scholar 

  28. Op den Camp, H.J.M.; Liem, K.D.; Meesters, P.; Hermans, J.M.H.; van der Drift, C.: Purification and characterization of the NADP-dependent glutamate dehydrogenase from Bacillus fastidiosus. Antonie Leeuwenhoek, 55, 303–311 (1989)

    Article  Google Scholar 

  29. Vancurova, I.; Vancura, A.; Volc, J.; Kopecky, J.; Neuzil, J.; Basarova, G.; Behal, V.: Purification and properties of NADP-dependent glutamate dehydrogenase from Streptomyces fradiae. J. Gen. Microbiol., 135, 3311–3318 (1989)

    PubMed  CAS  Google Scholar 

  30. Lilley, K.S.; Hornby, D.P.; Engel, P.C.: Purification, chemical modification and analysis of pH-dependence of the NADP+-dependent glutamate dehydrogenase of Escherichia coli. Biochem. Soc. Trans., 16, 876–877 (1988)

    CAS  Google Scholar 

  31. Martinez-Bilbao, M.; Martinez, A.; Urkijo, I.; Llama, M.J.; Serra, J.L.: Induction, isolation, and some properties of the NADPH-dependent glutamate dehydrogenase from the nonheterocystous cyanobacterium Phormidium laminosum. J. Bacteriol, 170, 4897–4902 (1988)

    PubMed  CAS  Google Scholar 

  32. Turner, A.C.; Lushbaugh, W.B.: Trichomonas vaginalis: characterization of its glutamate dehydrogenase. Exp. Parasitol., 67, 47–53 (1988)

    Article  PubMed  CAS  Google Scholar 

  33. Hatanaka, M.; Tachiki, T.; Kumagai, H.; Tochikura, T.: Distribution and some properties of glutamine synthetase and glutamate dehydrogenase in bifidobacteria. Agric. Biol. Chem., 51, 251–252 (1987)

    CAS  Google Scholar 

  34. Bascomb, N.F.; Schmidt, R.R.: Purification and partial kinetic and physical characterization of two chloroplast-localized NADP-specific glutamate dehydrogenase isoenzymes and their preferential accumulation in Chlorella sorokiniana cells cultured at low or high ammonium levels. Plant Physiol., 83, 75–84 (1987)

    Article  PubMed  CAS  Google Scholar 

  35. Weining, S.; Nicholas, D.J.D.: Purification and properties of NADP+-dependent glutamate dehydrogenase from Nitrobacter hamburgensis strain X14. Phytochemistry, 26, 2151–2153 (1987)

    Article  CAS  Google Scholar 

  36. Florencio, F.J.; Marques, S.; Candau, P.: Identification and characterization of a glutamate dehydrogenase in the unicellular cyanobacterium Synechocystis PCC 6803. FEBS Lett, 223, 37–41 (1987)

    Article  CAS  Google Scholar 

  37. Catmull, J.; Yellowlees, D.; Miller, D.J.: NADP+-dependent glutamate dehydrogenase from Acropora formosa. Mar. Biol., 95, 559–563 (1987)

    Article  CAS  Google Scholar 

  38. Cioni, P.; Cavaliere, M.G.; Fissi, A.; Balestreri, E.; Felicioli, R.: Glutamate dehydrogenase from E. coli kinetic structural and regulation studies. Ital. J. Biochem., 35, 175A–177A (1986)

    CAS  Google Scholar 

  39. Misono, H.; Goto, N.; Nagasaki, S.: Purification, crystallization and properties of NADP+-specific glutamate dehydrogenase from Lactobacillus fermentum. Agric. Biol. Chem., 49, 117–123 (1985)

    CAS  Google Scholar 

  40. Agrawal, A.K.; Rao, V.K.M.: Kinetic studies on glutamate dehydrogenase of Aspergillus ochraceus. Indian J. Biochem. Biophys., 21, 386–388 (1984)

    PubMed  CAS  Google Scholar 

  41. Botton, B.; Msatef, Y.: Purification and properties of NADP-dependent glutamate dehydrogenase from Sphaerostilbe repens. Physiol. Plant., 59, 438–444 (1983)

    Article  CAS  Google Scholar 

  42. Sarada, K.V.; Rao, N.A.; Venkitasubramanian, T.A.: Isolation and characterisation of glutamate dehydrogenase from Mycobacterium smegmatis CDC 46. Biochim. Biophys. Acta, 615, 299–308 (1980)

    PubMed  CAS  Google Scholar 

  43. Shimizu, H.; Kuratsu, T.; Hirata, F.: Purification and some properties of glutamate dehydrogenase from Proteus inconstans. J. Ferment. Technol., 57, 428–433 (1979)

    CAS  Google Scholar 

  44. Hemmilä, I.A.; Mäntsälä, P.I.: Purification and properties of glutamate synthase and glutamate dehydrogenase from Bacillus megaterium. Biochem. J., 173, 45–52 (1978)

    PubMed  Google Scholar 

  45. Leicht, W.; Werber, M.M.; Eisenberg, H.: Purification and characterization of glutamate dehydrogenase from Halobacterium of the Dead Sea. Biochemistry, 17, 4004–4010 (1978)

    Article  PubMed  CAS  Google Scholar 

  46. Juan, S.M.; Segura, E.L.; Cazzulo, J.J.: Purification and some properties of the NADP-linked glutamate dehydrogenase from Trypanosoma cruzi. Int. J. Biochem., 9, 395–400 (1978)

    Article  PubMed  CAS  Google Scholar 

  47. Camardella, L.; di Prisco, G.; Garofano, F.; Guerrini, A.M.: Purification and properties of NADP-dependent glutamate dehydrogenase from yeast nuclear fractions. Biochim. Biophys. Acta, 429, 324–330 (1976)

    PubMed  CAS  Google Scholar 

  48. Veronese, F.M.; Boccu, E.; Convenu, L.: Glutamate dehydrogenase from Escherichia coli: induction, purification and properties of the enzyme. Biochim. Biophys. Acta, 377, 217–228 (1975)

    PubMed  CAS  Google Scholar 

  49. Sakamoto, N.; Kotre, A.M.; Savageau, M.A.: Glutamate dehydrogenase from Escherichia coli: purification and properties. J. Bacteriol., 124, 775–783 (1975)

    PubMed  CAS  Google Scholar 

  50. Epstein, I.; Grossowicz, N.: Purification and properties of glutamate dehydrogenase from a thermophilic bacillus. J. Bacteriol., 122, 1257–1264 (1975)

    PubMed  CAS  Google Scholar 

  51. Coulton, J.W.; Kapoor, M.: Purification and some properties of the glutamate dehydrogenase of Salmonella typhimurium. Can. J. Microbiol., 19, 427–438 (1973)

    Article  PubMed  CAS  Google Scholar 

  52. Coulton, J.W.; Kapoor, M.: Studies on the kinetics and regulation of glutamate dehydrogenase of Salmonella typhimurium. Can. J. Microbiol., 19, 439–450 (1973)

    PubMed  CAS  Google Scholar 

Download references

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2005). Glutamate dehydrogenase (NADP+). In: Schomburg, D., Schomburg, I. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-37646-1_4

Download citation

Publish with us

Policies and ethics